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In this article, the authors discuss the increase of body weight of potential living liver donors to avoid the risk of small-for size syndrome in donor liver transplantation. They emphasize the evidence that excessive increase in body weight causes an increase in fat content of liver leading to metabolic syndrome development. The authors also say that it is more ethically acceptable when the approach will focus on recipient measures with inflow modulation compared to donor weight regulation.

Although overall donation and transplantation activity is higher in Europe than on other continents, differences between European countries in almost every aspect of transplantation activity (for example, in the number of transplantations, the number of people with a functioning graft, in rates of living versus deceased donation, and in the use of expanded criteria donors) suggest that there is ample room for improvement. Herein we review the policy and clinical measures that should be considered to increase access to transplantation and improve post-transplantation outcomes. This Roadmap, generated by a group of major European stakeholders collaborating within a Thematic Network, presents an outline of the challenges to increasing transplantation rates and proposes 12 key areas along with specific measures that should be considered to promote transplantation. This framework can be adopted by countries and institutions that are interested in advancing transplantation, both within and outside the European Union. Within this framework, a priority ranking of initiatives is suggested that could serve as the basis for a new European Union Action Plan on Organ Donation and Transplantation. [ABSTRACT FROM AUTHOR]