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Research on climate change, water quality, and their relationship is critical for human survival and development. It can help better mitigate climate change and contribute to appropriate water quality management strategies under uncertain challenges in the future. In this study, bibliometric analysis was used to provide a comprehensive review of the research field of climate change and water quality from 1990 to 2022. The extraction of documents was carried out from the Web of Science Core Collection database. VOSviewer, Bibliometrix R-package, and CiteSpace were used for analysis and scientific mapping. The results show that China, the United States, and Canada are the main countries driving this field, and China and the United States closely cooperate. It was also found that the areas of water eutrophication and climate change research had a close relationship and were the current research hotspots. Finally, it is revealed that the areas of sustainable development of climate change and water quality management, model simulation and method improvement between climate change and water quality, groundwater quality risk assessment driven by climate change, the impact of water on climate change, and expanding the research scale of the relationship between climate change and water quality will be the future research trends in this field. [ABSTRACT FROM AUTHOR]