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Background: The scarcity of sepsis epidemiologic data from most low- and middle-income countries (LMICs) hampered estimation of regional and global burden of the disease, and provided limited guidance for policy makers. We aimed to characterize and analyze the temporal trends of sepsis-related mortality in China, by population groups, underlying causes of death, geographic regions, and sociodemographic index (SDI) levels. Methods: Sepsis-related deaths were identified from the National Mortality Surveillance System (NMSS) of China from 2006 to 2020. Trends of sepsis-related mortality and years of life lost (YLLs), stratified by age, sex, underlying diseases, and regions were analyzed using the Jointpoint regression analysis. We investigated the association of SDI with trends of sepsis-related mortality. Results: In 2020, sepsis was estimated to be responsible for 986,929 deaths and 17.1 million YLLs in China. Age-standardized sepsis-related mortality significantly declined from 130.2 (95%CI, 129.4–131) per 100,000 population in 2006 to 76.6 (76.3–76.9) in 2020. Age-standardized YLLs decreased from 2172.7 (2169.4–2176) per 100,000 population in 2006 to 1271 (1269.8–1272.2) in 2020. Substantial variations of sepsis-related mortality and YLLs were observed between population groups and regions, with higher burden in males, the elderly, and western China. An inverse relation was noted between SDI and sepsis-related mortality or YLLs. Conclusions: Despite declining trends of age-standardized mortality and YLLs of sepsis in China, significant disparities between population groups and regions highlight a need for targeted policies and measures to close the gaps and improve the outcome of sepsis. [ABSTRACT FROM AUTHOR]

Granite–greenstone successions and associated tonalite–trondhjemite–granodiorite (TTG) suites constitute dominant components of Precambrian cratons. Here, we present petrology, geochemistry, zircon U–Pb geochronology, and Lu–Hf isotopes on monzonite, granodiorite, granite, and amphibolite from the Dengfeng Complex in the southern part of the North China Craton (NCC). Zircon U–Pb data yield weighted mean 207Pb/206Pb ages of 2498 ± 6 Ma for monzonite, 2481 ± 16 Ma for granodiorite, and 2475 ± 21 Ma for granite. Lu–Hf isotope systematics show εHf(t) values ranging from 1.3 to 6.7 and crustal model ages ( T DM C ) in the range of 2584–2934 Ma for the rocks. The monzonite, granodiorite, and granite show moderate total rare-earth element (REE) contents, enrichment in light REEs (LREE) and depletion in heavy REEs (HREE), negative Nb, Ta, and Ti anomalies, high Al2O3, Sr/Y, and (La/Yb)N ratios, with low Cr and Ni, indicating that the magma was possibly sourced from partial melting of the lower crust. The geochemical features of amphibolites are characterized by low SiO2, Na2O, K2O, Sr/Y, (La/Yb)N and high FeO, low total REEs values, limited LREE/HREE fractionation, and absence of obvious Ce anomaly, showing similarity to island arc magmatic rocks. Our results are consistent with the model of subduction and arc–continent collision in the Trans-North China Orogen during the Neoarchean to Paleoproterozoic. [ABSTRACT FROM AUTHOR]

Purpose: A population-level description and analysis of sepsis-related mortality in China is key to the planning and assessment of interventional strategies.Methods: Retrospective analysis of multiple cause of death (MCOD) recorded in the population-based national mortality surveillance system (NMSS) of China. All sepsis-related deaths occurring in 605 disease surveillance points (DSPs) covering 323.8 million population across China were included in our study. Age-standardized mortality and national estimate of sepsis-related deaths were estimated using the census population in 2010 and 2015, respectively.Results: In 2015, a total of 1,937,299 deaths occurring in any of the 605 DSPs and standardized sepsis-related mortality rate was 66.7 (95% confidence interval [CI] 66.4-67.0) deaths per 100,000 population. This produced a national estimate of 1,025,997 sepsis-related deaths. Sepsis-related mortality rates exhibited significant geographic variation. In multilevel analysis, male sex (rate ratio [RR] 1.582, 95% CI 1.570-1.595), increasing age (RR 1.914 for 5-year group, 95% CI 1.910-1.917), and presence of comorbidity (RR 2.316, 95% CI 2.298-2.335) were independently associated with increased sepsis-related mortality. Higher disposable income (RR 0.717 for the fourth interquartile range vs. the first interquartile range, 95% CI 0.515-0.978) and mean years of education (RR 0.808 for the fourth interquartile range vs. the first interquartile range, 95% CI 0.684-0.955) were negatively associated with sepsis-related mortality. However, population-based hospital doctors were not significantly associated with sepsis-related mortality.Conclusions: The standardized sepsis-related mortality rate in China was high and varied according to socioeconomic indices, even though some uncertainty remained. [ABSTRACT FROM AUTHOR]

31 topsoil samples were collected by grid method in Xiaodian sewage irrigation area, Taiyuan City, North of China. The concentrations of 16 kinds of polycyclic aromatic hydrocarbons (PAHs) were determined by gas chromatograph coupled with mass spectrum. Generally speaking, the distribution order of PAHs in the area is: those with five and six rings > those with four rings > those with two and three rings. Source apportionment shows a significant zonation of the source of PAHs: the civil coal pollution occurred in the north part, the local and far factory pollution happened in the middle area and the mixed pollution sources from coal and wood combustion, automotive emission, presented in the south area. The distribution of PAHs has a definite relationship with the sewage water flow and soil adsorption. The related coefficient between PAHs and physicochemical property showed there was a negative correlation between pH, silt, clay and PAHs while there was a positive correlation between total organic carbon, sand and PAHs. [ABSTRACT FROM AUTHOR]

The article reflects on critical care research in china which is lacking behind due to several reasons. It mentions reasons including the lack of training in clinical research, inadequate resources and lack of language proficiency. It states that multiple resolutions may improve critical care research which include better understanding of good clinical practice and collaborative research in critical care.