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We reflect on the extent to which the UK Events Research Programme adhered to four principles of design and evaluation in assessing risk of transmission from attending such mass events as football matches and festivals, and lessons learned. [ABSTRACT FROM AUTHOR]

Failings in patient care and quality in NHS Trusts have become a recurring theme over the past few years. In this paper, we examine the Care Quality Commission's Guidance about Compliance: Essential Standards of Quality and Safety and ask how NHS Trusts might be better supported in fulfilling the regulations specified therein. We argue that clinical ethics committees (CECs) have a role to play in this regard. We make this argument by attending to the many ethical elements that are highlighted in the Commission's Regulations and by providing practical examples of how CECs can (and in some case already do) provide ethics support to health professionals and trusts. Although CECs have been traditionally associated with case consultation, i.e., discrete problems caused by individual circumstances, in the previous 10 years the literature suggests that clinical ethics services have become more integrated into the life of the health care organization and are increasing construed as proactive agents of systematic change. We provide evidence from a recent survey of UK clinical ethics services that this trend is present in the UK. [ABSTRACT FROM AUTHOR]

The International Nucleotide Sequence Database Collaboration (INSDC) exchanges sequence data on a daily basis across its three member organizations in the USA, UK and Japan. This paper studies how this sequence database in MySQL can best take advantage of the increased transfer bandwidth of a Grid-optimized data communication protocol. Within the context of the UK Government Project Grid-oriented Storage (GOS) and the EC Project EuroAsiaGrid, GOS File System (GOS-FS) has been developed in our lab, which melds distributed file system technology with high performance data transfer techniques to meet the needs of WAN/Grid-based virtual organizations. A real-world test shows that the INSDC sequence database backing up operation, mysqldump, over the GOS-FS protocol beats those over the classic NFS protocol by 6 times over the link between Cambridge and Tokyo. Best of all, the multi-streamed GOS-FS protocol remains fully compatible with existing IF infrastructures. [ABSTRACT FROM AUTHOR]