Search

Your search keyword '"Bioenergy Research Center (US)"' showing total 2 results
Start Over Author "Bioenergy Research Center (US)" Publisher springer nature
2 results on '"Bioenergy Research Center (US)"'

1. Macroevolutionary diversity of traits and genomes in the model yeast genus Saccharomyces

Author

European Commission, Research Council of Norway, Generalitat Valenciana, National Science Foundation (US), Great Lakes Bioenergy Research Center (US), National Natural Science Foundation of China, 0000-0001-9912-8802, 0000-0002-1916-0122, 0000-0001-7909-2339, 0000-0001-5971-3337, 0000-0003-3028-6866, 0000-0003-2103-1060, 0000-0001-8145-5274, 0000-0002-2180-8135, 0000-0001-9823-6430, 0000-0002-5309-6718, 0000-0001-5088-7461, Peris Navarro, David, Ubbelohde, Emily J., Kuang, Meihua Christina, Kominek, Jacek, Langdon, Quinn K., Adams, Marie, Koshalek, Justin A., Hulfachor, Amanda Beth, Opulente, Dana A., Hall, David J., Hyma, Katie, Fay, Justin C., Leducq, Jean-Baptiste, Charron, Guillaume, Landry, Christian R., Libkind, Diego, Gonçalves, Carla, Gonçalves, Paula, Sampaio, José Paulo, Wang, Qi-Ming, Bai, Feng-Yan, Wrobel, Russel L., Hittinger, Chris Todd, European Commission, Research Council of Norway, Generalitat Valenciana, National Science Foundation (US), Great Lakes Bioenergy Research Center (US), National Natural Science Foundation of China, 0000-0001-9912-8802, 0000-0002-1916-0122, 0000-0001-7909-2339, 0000-0001-5971-3337, 0000-0003-3028-6866, 0000-0003-2103-1060, 0000-0001-8145-5274, 0000-0002-2180-8135, 0000-0001-9823-6430, 0000-0002-5309-6718, 0000-0001-5088-7461, Peris Navarro, David, Ubbelohde, Emily J., Kuang, Meihua Christina, Kominek, Jacek, Langdon, Quinn K., Adams, Marie, Koshalek, Justin A., Hulfachor, Amanda Beth, Opulente, Dana A., Hall, David J., Hyma, Katie, Fay, Justin C., Leducq, Jean-Baptiste, Charron, Guillaume, Landry, Christian R., Libkind, Diego, Gonçalves, Carla, Gonçalves, Paula, Sampaio, José Paulo, Wang, Qi-Ming, Bai, Feng-Yan, Wrobel, Russel L., and Hittinger, Chris Todd

Abstract

Species is the fundamental unit to quantify biodiversity. In recent years, the model yeast Saccharomyces cerevisiae has seen an increased number of studies related to its geographical distribution, population structure, and phenotypic diversity. However, seven additional species from the same genus have been less thoroughly studied, which has limited our understanding of the macroevolutionary events leading to the diversification of this genus over the last 20 million years. Here, we show the geographies, hosts, substrates, and phylogenetic relationships for approximately 1,800 Saccharomyces strains, covering the complete genus with unprecedented breadth and depth. We generated and analyzed complete genome sequences of 163 strains and phenotyped 128 phylogenetically diverse strains. This dataset provides insights about genetic and phenotypic diversity within and between species and populations, quantifies reticulation and incomplete lineage sorting, and demonstrates how gene flow and selection have affected traits, such as galactose metabolism. These findings elevate the genus Saccharomyces as a model to understand biodiversity and evolution in microbial eukaryotes.

Published
2023

2. Synthetic hybrids of six yeast species

Author

European Commission, National Science Foundation (US), Great Lakes Bioenergy Research Center (US), National Institute of Food and Agriculture (US), Peris Navarro, David, Alexander, William G., Fisher, Kaitlin J., Moriarty, Ryan V., Basuino, Mira G., Ubbelohde, Emily J., Wrobel, Russell L., Hittinger, Chris Todd, European Commission, National Science Foundation (US), Great Lakes Bioenergy Research Center (US), National Institute of Food and Agriculture (US), Peris Navarro, David, Alexander, William G., Fisher, Kaitlin J., Moriarty, Ryan V., Basuino, Mira G., Ubbelohde, Emily J., Wrobel, Russell L., and Hittinger, Chris Todd

Abstract

Allopolyploidy generates diversity by increasing the number of copies and sources of chromosomes. Many of the best-known evolutionary radiations, crops, and industrial organisms are ancient or recent allopolyploids. Allopolyploidy promotes differentiation and facilitates adaptation to new environments, but the tools to test its limits are lacking. Here we develop an iterative method of Hybrid Production (iHyPr) to combine the genomes of multiple budding yeast species, generating Saccharomyces allopolyploids of at least six species. When making synthetic hybrids, chromosomal instability and cell size increase dramatically as additional copies of the genome are added. The six-species hybrids initially grow slowly, but they rapidly regain fitness and adapt, even as they retain traits from multiple species. These new synthetic yeast hybrids and the iHyPr method have potential applications for the study of polyploidy, genome stability, chromosome segregation, and bioenergy.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results