1. Focal screening and treatment for malaria: defining the sentinel population
- Author
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Victor Osoti, Elizabeth Marube, Amrish Baidjoe, Euniah Makori, Chrispin Owaga, Gillian Stresman, Chris Drakeley, Wycliffe Odongo, Jonathan Cox, Jennifer C. Stevenson, Shehu Shagari, and Teun Bousema
- Subjects
Pathology ,medicine.medical_specialty ,Rapid diagnostic test ,education.field_of_study ,High prevalence ,business.industry ,Population ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,Diagnostic tools ,medicine.disease ,lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] ,Infectious Diseases ,Malaria transmission ,Poster Presentation ,medicine ,Field based ,Parasitology ,Intensive care medicine ,education ,business ,GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries) ,Mass screening ,Malaria - Abstract
Background Mass screening and treatment campaigns have had limited success in curbing malaria transmission, possibly as a consequence of the high prevalence of subpatent infections that are missed using the currently available field based diagnostic tools. It has been shown that subpatent malaria infections are more likely to occur in households where patent infections are identified suggesting that it may be possible to employ a more focal approach to treatment campaigns using sentinel cases as markers for the presence of a subpatent reservoir. However, it is not known which definition of sentinel case to rely on for initiation of treatment would provide optimal coverage of the parasite reservoir.
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