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Laser sensing technology is used to detect the pavement. In the pavement cross-section rut detection, multi-channel laser sensors are used to collect the three-dimensional information of the uneven cross-section direction of the road surface at the same time. In the pavement structure depth detection, two laser sensors are used to collect the three-dimensional information of the road surface structure depth at the same time. Linear regression and quadratic regression algorithm are used to reduce the pavement cross-section rut and structure depth detection. On this basis, the embedded multi-channel laser pavement rutting detection system and laser pavement structure depth detection system are researched and developed; many field tests and application tests have been carried out. Through comparison and verification, the system has strong reliability, small error, and fast detection speed, which is suitable for road detection of different structures. [ABSTRACT FROM AUTHOR]

Schisandrin A (Sch A) is a lignin extracted from the fruit of Schisandra chinensis, which has potential anti-inflammatory properties and is used for treating various inflammatory diseases. In this study, we aimed to evaluate the anti-inflammatory effects of Sch A and the underlying mechanisms in animal models of acute inflammation. First, the anti-inflammatory effects of Sch A were evaluated preliminarily in an animal model of xylene-induced ear edema. Sch A pretreatment significantly decreased the degree of edema and inhibited telangiectasia in the ear. Second, a mouse model of paw edema was used to investigate the anti-inflammatory effects and mechanisms of Sch A. Pretreatment with Sch A significantly inhibited carrageenan-induced paw edema in mice. Hematoxylin-eosin (HE) staining of paw tissues demonstrated that Sch A inhibited the infiltration of inflammatory cells in the mouse model of paw edema. Enzyme-linked immunosorbent assay (ELISA) results indicated that the levels of inflammatory factors decreased. The western blot and immunohistochemical assay results revealed that the toll-like receptor 4/nuclear factor kappa-B (TLR4/NF-κB) pathway could play a role in the anti-inflammatory functions of Sch A. The findings demonstrated that Sch A exerts anti-inflammatory effects and may provide possible strategies for the treatment of inflammatory diseases. [ABSTRACT FROM AUTHOR]