1. Green synthesis of nanohydroxy apatite using Calotropis procera and Wrightia tinctoria plant latex serum extract for biomedical application.
- Author
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Suba Sri, M., Subhashini, M., Devi, M. Kalpana, Devi, R. Jayakala, and Usha, R.
- Abstract
Medical textiles have become increasingly important and extend the strong protection role in the healthcare industry. The goal of this study was to improve conventional cotton gauze into advanced biomedical specifications with antimicrobial activity. The cotton gauze fabrics were modified by in situ wet chemical precipitation of hydroxyapatite nanoparticles (HAp NP) with Calotropis procera and Wrightia tinctoria plant latex serum extract. The developed nanoparticles were initially examined by UV–visible spectrophotometer with maximum absorbance peak at 274 nm for Calotropis procera and 286 nm for Wrightia tinctoria. To determine the lattice formation and average crystal size, X-ray diffraction (XRD) study was done and the size was observed as 31.13 μm and 29.18 μm for Calotropis procera and Wrightia tinctoria serum extract hydroxyapatite nanoparticles respectively. Fourier transform infra-red spectroscopy (FTIR) confirmed the presence of functional groups such as the carbonate and phosphate group in both the developed nanoparticle as they are the important agents for forming Hap. The scanning electron microscope (SEM) result confirms the developed nanoparticle was hexagonal in shape with polycrystalline morphology. Deposition of Calotropis procera and Wrightia tinctoria HAp NP onto cotton gauze fabrics resulted in significant antimicrobial activity with zone of inhibition against Candida albicans, Aspergillus niger, Staphylococcus aureus, and Escherichia coli. Hence, the present work highlighted the development of plant extract-mediated hydroxyapatite nanoparticles having excellent antibacterial properties and it can be recommended for medical application. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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