1. Left ventricular flow propagation velocity measurement: Is it cast in stone?
- Author
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Chan, Bee, Yeoh, Hak, Liew, Yih, Aziz, Yang, Sridhar, Ganiga, Hamilton-Craig, Christian, Platts, David, Lim, Einly, Chan, Bee Ting, Yeoh, Hak Koon, Liew, Yih Miin, Aziz, Yang Faridah Abdul, and Sridhar, Ganiga Srinivasaiah
- Subjects
LEFT heart ventricle ,PHASE contrast magnetic resonance imaging ,MITRAL valve ,MEDICAL imaging systems ,MEDICAL statistics ,HEART physiology ,BLOOD flow measurement ,DIASTOLE (Cardiac cycle) ,CARDIAC contraction ,HEART ventricles ,HEMODYNAMICS ,RESEARCH funding ,PHYSIOLOGY - Abstract
This study aims to investigate the measurement of left ventricular flow propagation velocity, V p, using phase contrast magnetic resonance imaging and to assess the discrepancies resulting from inflow jet direction and individual left ventricular size. Three V p measuring techniques, namely non-adaptive (NA), adaptive positions (AP) and adaptive vectors (AV) method, were suggested and compared. We performed the comparison on nine healthy volunteers and nine post-infarct patients at four measurement positions, respectively, at one-third, one-half, two-thirds and the conventional 4 cm distances from the mitral valve leaflet into the left ventricle. We found that the V p measurement was affected by both the inflow jet direction and measurement positions. Both NA and AP methods overestimated V p, especially in dilated left ventricles, while the AV method showed the strongest correlation with the isovolumic relaxation myocardial strain rate (r = 0.53, p < 0.05). Using the AV method, notable difference in mean V p was also observed between healthy volunteers and post-infarct patients at positions of: one-half (81 ± 31 vs. 58 ± 25 cm/s), two-thirds (89 ± 32 vs. 45 ± 15 cm/s) and 4 cm (98 ± 23 vs. 47 ± 13 cm/s) distances. The use of AV method and measurement position at one-half distance was found to be the most suitable method for assessing diastolic dysfunction given varying left ventricular sizes and inflow jet directions. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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