1. Facile Synthesis of Boronate Affinity-Based Molecularly Imprinted Monolith with Reduced Capturing pH Towards Cis-Diol-Containing Compounds.
- Author
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Peng, Chao, Lan, Yao-Han, Sun, Lu, Chen, Xin-Zhu, Chi, Shuai-Shuai, Zheng, Chao, Dong, Lin-Yi, and Wang, Xian-Hua
- Abstract
Here, we report a novel boronate affinity-based surface molecularly imprinted monolith (BA-SMIM), which was fabricated by simple two-step atom-transfer radical polymerization (ATRP) strategy. A boronate affinity-based surface non-imprinted monolith (BA-SNIM) was prepared as control. The synthesis parameters of BA-SMIM were optimized, and the resultant BA-SMIM was characterized in detailed. In both aqueous-rich and organic-rich mobile phases, the BA-SMIM could recognize cis-diol-containing compounds mainly due to the imprinting effect. The chlorogenic acid and rosmarinic acid with two cis-diols could interact synergistically with two imprinting cavities of BA-SMIM, so they retained longer on BA-SMIM than one cis-diol-containing compounds. In addition, the capturing pH reduced from 8.6 on BA-SNIM and to 7.8 on BA-SMIM for one cis-diol-containing compounds, and from 7.4 on BA-SNIM and to 7.0 on BA-SMIM for two cis-diol-containing compounds, respectively. The reducing of capturing pH value on BA-SMIM may be attributed to the nanoconfinement effect of imprinting cavity. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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