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In conclusion, the finding that tumor genetics, pathology, and location are significantly correlated with language reorganization in brain tumor patients might contribute to the choice of the optimal surgical procedure and timing. Against this background, Pasquini et al. described a retrospective investigation of 405 patients with left-hemispheric tumors and 49 patients with right-hemispheric tumors as controls [[2]]. 8895248 2 Pasquini L, Yildirim O, Silveira P. Effect of tumor genetics, pathology, and location on fMRI of language reorganization in brain tumor patients. In terms of the effect of tumor location on language reorganization, significant associations exist between the frontal LI, Broca LI, and tumor involvement of Broca's area (BA). [Extracted from the article]