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Objective: To investigate the dry eye symptoms after cataract surgery in MGD patients and their relationships Methods: The study included 115 patients (115 eyes) with age-related cataract that underwent uncomplicated cataract surgery, and the patients were divided into two groups according to the MGD diagnostic criteria: group A (MGD group) and group B (control group). Schirmer I test (ST-I), tear breakup time (TBUT), and corneal fluorescein staining (CFS) were performed preoperatively and at 3 days, 7 days, 14 days, and 30 days postoperatively. We also measured eyelid meibomian gland morphology, meibomian gland expression, and meibum character scores before and after the cataract surgery. Results: Postoperatively, in group A, TBUT decreased and CFS scores increased significantly. ST-I increased in the early postoperative course but decreased later. The eyelid margin morphology scores and meibomian gland expression scores of group A significantly increased after the cataract operation. Thus, patients with MGD may have a greater chance of developing the dry eye disease after cataract surgery. Cataract surgery may aggravate the signs of MGD, and the severity of MGD may positively correlate with TBUT, CFS, and corneal lesions after surgery. Conclusions: The characteristics of dry eye after cataract surgery in patients with MGD are different from common cataract patients, changes in the early postoperative phase to the ocular surface were caused by surgical factors, and the damages to epithelial function in the later postoperative phase were mainly associated with the inflammation of the meibomian gland and eyelid. [ABSTRACT FROM AUTHOR]

A series of copper(II) with 2-aminobenzonitrile and 3-(2-oxo-pyrrolidin-yl)-propionitrile were first synthesized and characterized, and the reaction of these nitriles with Cu(OAc)·HO or CuCl·2HO in ethanol resulted in the production of three novel copper complexes, I, II, and III. In addition, we obtained the manganese (II) oxygen complex ( IV) in the process of synthesis of the manganese (II) nitrogen complex, in which o-phenylenediamine was used as the ligands to react with MnCl·4HO. The structure of each complex was determined by X-ray diffraction analysis. Each complex was also characterized using elemental analysis, H NMR and IR. The complexes were then all used to catalyze the Henry reaction, and moderate catalytic results were achieved. Graphical Abstract: A series of copper(II) with 2-aminobenzonitrile and 3-(2-oxo-pyrrolidin-yl)-propionitrile were first synthesized and characterized, and the reaction of these nitriles with Cu(OAc)·HO or CuCl·2HO in ethanol resulted in the production of three novel copper complexes, I, II, and III. In addition, we obtained the manganese (II) oxygen complex ( IV) in the process of synthesis of the manganese (II) nitrogen complex, in which o-phenylenediamine was used as the ligands to react with MnCl·4HO. The structure of each complex was determined by X-ray diffraction analysis. Each complex was also characterized using elemental analysis, H NMR and IR. The complexes were then all used to catalyze the Henry reaction, and moderate catalytic results were achieved. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]