1. Prevalence of ocular manifestations in hereditary hemorrhagic telangiectasia.
- Author
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Urban Geisthoff and Klaus Ruprecht
- Subjects
- *
OCULAR manifestations of general diseases , *TELANGIECTASIA , *VASODILATION , *DIAGNOSIS - Abstract
Abstract Background  Hereditary hemorrhagic telangiectasia (HHT) is a systemic disorder of the fibrovascular tissue. Few data have been published on the frequency of ophthalmologic manifestations. The aim of this study was to assess this frequency. Methods  A prospective observational cross-sectional study was conducted in a multitude of clinical practices and in a tertiary referral center. The main outcome measure was the number of vascular malformations detected by an ophthalmologic inspection of the retina and the conjunctivae in both eyes in a random sample of patients with HHT. Results  No retinal telangiectases were observed in any of the 75 patients (150 eyes) examined. Conjunctival telangiectases were detected in 28 of 74 patients (47 of 148 eyes). Conclusions  The prevalence of retinal telangiectases seems to be lower than 1/75 ( [ABSTRACT FROM AUTHOR]
- Published
- 2007
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