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Purpose: This study aimed to identify all relevant randomized controlled trials (RCT) and prospective non-RCTs to further investigate whether percutaneous vertebral augmentation (PVA) was associated with clinical and radiological subsequent fractures on unoperated levels. Methods: We systematically searched PubMed, EMBASE, Cochrane library, Google Scholar, web of science, and ClinicalTrial.gov from the establishment of the database to January 2020. All eligible studies comparing subsequent fractures after PVA with those after conservative treatment (CT) were incorporated. The pooled risk ratio (RR) with its 95% confidence intervals (95% CIs) was used. Heterogeneity, sensitivity, and publication bias analyses were performed. Results: In all, 32 studies were included in the study: 82/512 patients (16.02%) and 58/433 patients (13.39%) had clinical subsequent fractures in the PVA group and CT group, respectively. No significant differences were observed between the two groups [RR = 1.22, 95% CI 0.70–2.12, P = 0.49]. Further, 175/837 patients (20.91%) in the PVA group and 160/828 patients (19.32%) in the CT group had radiological subsequent fractures. No significant difference was observed between groups [RR = 0.91, 95% CI 0.71–2.12, P = 1.16]. Further, no statistical difference was observed on subgroup analysis between RCTs and non-RCTs or PVP and PKP. Conclusion: Our systematic review revealed that subsequent fractures on unoperated levels were not associated with PVA, regardless of whether they were clinical or radiological subsequent fractures. [ABSTRACT FROM AUTHOR]

Two novel metal-organic compounds [Zn(mtp)(pdc)] ( 1) and [Cd(mtp)(bdc)·2HO] ( 2) [mtp = 2-(2-methoxy-phenyl)-1 H-1,3,7,8-tetraaza-cyclopenta[l]phenanthrene, pdc = 5-methyl-2 H-pyridine-1,3-dicarboxylic acid, bdc = terephthalic acid] have been synthesized by hydrothermal reactions and characterized by elemental analysis, thermogravimetric (TG) analysis, infrared spectrum and single-crystal X-ray diffraction. Single-crystal X-ray diffraction reveals that 1 exhibits one-dimensional (1D) chain structure, and 2 shows 2D layer architecture. TG analysis shows clear courses of weight loss, which correspond to the decomposition of different ligands. We also discussed the luminescent properties for the ligands and compounds 1- 2. Compounds 1 and 2 may be good candidate for potential photoluminescence materials, because it is highly thermally stable and insoluble in water and common organic solvents. [ABSTRACT FROM AUTHOR]