34 results on '"Zhi Zeng"'
Search Results
2. Study on Joint Method of 3D Acoustic Emission Source Localization Simplex and Grid Search Scanning.
- Author
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Liu, Wei-jian, Wang, Hao-nan, Xiao, Yang, Hou, Meng-jie, Dong, Sen-sen, Zhang, Zhi-zeng, and Lu, Gao-ming
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ACOUSTIC localization ,ACOUSTIC emission ,ROCK testing ,GEOMETRY ,ALGORITHMS - Abstract
Acoustic emission (AE) source localization is a fundamental element of rock fracture damage imaging. To improve the efficiency and accuracy of AE source localization, this paper proposes a joint method comprising a three-dimensional (3D) AE source localization simplex method and grid search scanning. Using the concept of the geometry of simplexes, tetrahedral iterations were first conducted to narrow down the suspected source region. This is followed by a process of meshing the region and node searching to scan for optimal solutions, until the source location is determined. The resulting algorithm was tested using the artificial excitation source localization and uniaxial compression tests, after which the localization results were compared with the simplex and exhaustive methods. The results revealed that the localization obtained using the proposed method is more stable and can be effectively avoided compared with the simplex localization method. Furthermore, compared with the global scanning method, the proposed method is more efficient, with an average time of 10%–20% of the global scanning localization algorithm. Thus, the proposed algorithm is of great significance for laboratory research focused on locating rupture damages sustained by large-sized rock masses or test blocks. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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3. Switching, explosion, and chaos of multi-wavelength soliton states in ultrafast fiber lasers.
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Si, Zhi-Zeng, Wang, Yue-Yue, and Dai, Chao-Qing
- Abstract
Because of the complexity and difficulty of realizing a multi-wavelength soliton state, reports on its internal dynamic characteristics are scarce. In this study, the switching and periodic soliton explosion processes of the multi-wavelength soliton state in a negative dispersion passively mode-locked fiber laser are realized. The generation of the multi-wavelength soliton state undergoes the process of noise, oscillation, and stable mode-locking, and the splitting and annihilation of solitons with different group velocities directly impact the generation and disappearance of three wavelengths. Positive and negative dispersion lead to different group velocities of solitons. The presence and displacement of solitons with different group velocities cause soliton collisions, which lead to soliton explosions. A soliton experiences relative phase oscillation, chaos, and oscillation, as well as convergence and separation before and after an explosion. With an increase in parameters related to pump power, single-soliton oscillation, multi-wavelength solitons, and chaos are found in experiments and simulations, proving the relevance and reliability between simulation and experimental results. This work promotes the dynamical study of multi-soliton collisions in nonlinear science and the development of chaos theory in multi-comb lasers. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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4. Rock burst prevention and control of multifield coupling in longwall working face.
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Liu, Wei-jian, Hou, Meng-jie, Dong, Sen-sen, Xiao, Yang, Wang, Hao-nan, Deng, Zhi-gang, and Zhang, Zhi-zeng
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ROCK bursts ,MINE accidents ,LONGWALL mining ,GAS bursts ,COAL mining ,FLOOD warning systems ,COAL gas - Abstract
This study numerically examines the evolution of the stress and displacement fields of rock sur-rounding an oblique normal fault in the longwall working face of a mine. The aim is to determine the law of activation of an abnormal geological body containing coal and rock mass and to provide timely warnings of geological hazards, such as coal and gas bursts, rock bursts, and flooding during coal mining. A high-precision microseismic monitoring system was used to monitor the activation of and damage to the rock surrounding the mine. The results of numerical simulations coupled with those of microseismic monitoring showed that the coal and rock mass near the fault and goaf was situated in an area of high stress, with a high frequency and energy of microseismic events, wherein changes in the displacement of the roof were more significant when the working face was pushed to the fault layer. The combined analysis provides information on the activation of rock surrounding the coal mine and can be used to provide early warnings of mining accidents. The results provide a reference for the safe mining of the working face and technical guidance for the design parameters of pressure relief holes. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Preparation of porous silica from natural chlorite via selective acid leaching and its application in methylene blue adsorption.
- Author
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Wang, Zhi-zeng, Zhao, Qin-yi, Wang, Dong-yun, and Cui, Chong
- Abstract
Copyright of Journal of Central South University is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
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6. Study of the mechanisms of streamline-adjustment-assisted heterogeneous combination flooding for enhanced oil recovery for post-polymer-flooded reservoirs.
- Author
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Du, Qing-Jun, Pan, Guang-Ming, Hou, Jian, Guo, Lan-Lei, Wang, Rong-Rong, Xia, Zhi-Zeng, and Zhou, Kang
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ENHANCED oil recovery ,RESERVOIRS ,POLYMER colloids - Abstract
Streamline-adjustment-assisted heterogeneous combination flooding is a new technology for enhanced oil recovery for post-polymer-flooded reservoirs. In this work, we first carried out a series of 2D visualization experiments for different chemical flooding scenarios after polymer flooding. Then, we explored the synergistic mechanisms of streamline-adjustment-assisted heterogeneous combination flooding for enhanced oil recovery and the contribution of each component. Test results show that for single heterogeneous combination flooding, the residual oil in the main streamline area after polymer flooding is ready to be driven, but it is difficult to be recovered in the non-main streamline area. Due to the effect of drainage and synergism, the streamline-adjustment-assisted heterogeneous combination flooding diverts the injected chemical agent from the main streamline area to the non-main streamline area, which consequently expands the active area of chemical flooding. Based on the results from the single-factor contribution of the quantitative analysis, the contribution of temporary plugging and profile control of branched preformed particle gels ranks in the first place and followed by the polymer profile control and the effect of streamline adjustment. On the contrary, the surfactant contributes the least to enhance the efficiency of oil displacement. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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7. Noise-assisted MEMD based relevant IMFs identification and EEG classification.
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She, Qing-shan, Ma, Yu-liang, Meng, Ming, Xi, Xu-gang, and Luo, Zhi-zeng
- Abstract
Noise-assisted multivariate empirical mode decomposition (NA-MEMD) is suitable to analyze multichannel electroencephalography (EEG) signals of non-stationarity and non-linearity natures due to the fact that it can provide a highly localized time-frequency representation. For a finite set of multivariate intrinsic mode functions (IMFs) decomposed by NA-MEMD, it still raises the question on how to identify IMFs that contain the information of inertest in an efficient way, and conventional approaches address it by use of prior knowledge. In this work, a novel identification method of relevant IMFs without prior information was proposed based on NA-MEMD and Jensen-Shannon distance (JSD) measure. A criterion of effective factor based on JSD was applied to select significant IMF scales. At each decomposition scale, three kinds of JSDs associated with the effective factor were evaluated: between IMF components from data and themselves, between IMF components from noise and themselves, and between IMF components from data and noise. The efficacy of the proposed method has been demonstrated by both computer simulations and motor imagery EEG data from BCI competition IV datasets. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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8. Aircraft Landing Scheduling Based on Semantic Agent Negotiation Mechanism.
- Author
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Huang, Zhao-Tong, Song, Xue-Yan, Sun, Ji-Zhou, and Li, Zhi-Zeng
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- 2012
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9. A Scatter Search Methodology for the Aircraft Conflict Resolution Problem.
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Li, Zhi-Zeng, Song, Xue-Yan, Sun, Ji-Zhou, and Huang, Zhao-Tong
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- 2012
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10. A Laboratory Comparison of Arbitration Mechanisms: FOA and AFOA.
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Beckmann, M., Künzi, H. P., Fandel, G., Trockel, W., Basile, A., Drexl, A., Dawid, H., Inderfurth, K., Kürsten, W., Schittko, U., Oda, Sobei Hidenori, Deck, Cary, Farmer, Amy, and Dao-Zhi Zeng
- Abstract
Given its lower costs relative to litigation, arbitration is rapidly increasing as a mechanism to settle disputes. While it has traditionally been employed in labor disputes, arbitration has several characteristics that are making it an increasingly attractive option in numerous forms of dispute. First, relative to traditional litigation, arbitration is significantly less costly. However, in addition to the lower expense, arbitration generally places greater restrictions on discovery thereby lessening the competitive information that a business may have to reveal in the resolution of a dispute. Further, these limitations tend to hasten the process further reducing both direct and indirect costs. As mentioned by Fuller [9], Apple Computer saved over $4 million in legal fees by using arbitration in a case with the IRS and simultaneously prevented the revelation of proprietary information which would have occurred in standard litigation. As a result of these characteristics, arbitration has become the dispute resolution of choice for numerous business transactions. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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11. Creeping Motion of Self Interstitial Atom Clusters in Tungsten.
- Author
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Wang Huai Zhou, Chuan Guo Zhang, Yong Gang Li, and Zhi Zeng
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ATOMS ,TUNGSTEN ,MOLECULAR dynamics ,BINDING energy ,DIFFUSION processes ,IRRADIATION - Abstract
The formation and motion features of self interstitial atom (SIA) clusters in tungsten are studied by molecular dynamics (MD) simulations. The static calculations show that the SIA clusters are stable with binding energy over 2 eV. The SIA clusters exhibit a fast one dimensional (1D) motion along 〈111〉. Through analysis of the change of relative distance between SIAs, we find that SIAs jump in small displacements we call creeping motion, which is a new collective diffusion process different from that of iron. The potential energy surface of SIAs implicates that the creeping motion is due to the strong interaction between SIAs. These imply that several diffusion mechanism for SIA clusters can operate in BCC metals and could help us explore deep insight into the performance of materials under irradiation. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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12. Screening for Voltage-Gated Sodium Channel Interacting Peptides.
- Author
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Er Meng, Tian-Fu Cai, Hui Zhang, Si Tang, Meng-Jie Li, Wen-Ying Li, Peng-Fei Huang, Kai Liu, Lei Wu, Ling-Yun Zhu, Long Liu, Kuan Peng, Xian-Dong Dai, Hui Jiang, Xiong-Zhi Zeng, Song-Ping Liang, and Dong-Yi Zhang
- Subjects
SODIUM channels ,NEUROTOXIC agents ,EXTRACELLULAR space ,PEPTIDE spectra ,MEMBRANE proteins - Abstract
The voltage-gated sodium channel (VGSC) interacting peptide is of special interest for both basic research and pharmaceutical purposes. In this study, we established a yeast-two-hybrid based strategy to detect the interaction(s) between neurotoxic peptide and the extracellular region of VGSC. Using a previously reported neurotoxin JZTX-III as a model molecule, we demonstrated that the interactions between JZTX-III and the extracellular regions of its target hNa
v 1.5 are detectable and the detected interactions are directly related to its activity. We further applied this strategy to the screening of VGSC interacting peptides. Using the extracellular region of hNav 1.5 as the bait, we identified a novel sodium channel inhibitor SSCM-1 from a random peptide library. This peptide selectively inhibits hNav 1.5 currents in the whole-cell patch clamp assays. This strategy might be used for the large scale screening for target-specific interacting peptides of VGSCs or other ion channels. [ABSTRACT FROM AUTHOR]- Published
- 2014
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13. Pressure-induced planar N6 rings in potassium azide.
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Jie Zhang, Zhi Zeng, Hai-Qing Lin, and Yan-Ling Li
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EVOLUTIONARY algorithms , *POLYMERIZATION , *ENERGY density , *CONJUGATE gradient methods , *DENSITY functional theory - Abstract
The first-principles method and the evolutionary algorithm are used to identify stable high pressure phases of potassium azide (KN3). It has been verified that the stable phase with space group I4/mcm below 22 GPa, which is consistent with the experimental result, will transform into the C2/m phase with pressure increasing. These two phases are insulator with N-3 anions. A metallic phase with P6/mmm symmetry is preferred above 40 GPa, and the N atoms in this structure form six-membered rings which are important for understanding the pressure effect on N-3 anions and phase transitions of KN3. Above the studied pressure (100 GPa), a polymerization of N6 rings may be obtained as the result of the increasing compactness. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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14. Formation of Nanofoam carbon and re-emergence of Superconductivity in compressed CaC6.
- Author
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Yan-Ling Li, Wei Luo, Xiao-Jia Chen, Zhi Zeng, Hai-Qing Lin, and Ahuja, Rajeev
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SUPERCONDUCTIVITY ,ELECTRIC conductivity ,SUPERFLUIDITY ,CRYOELECTRONICS ,ELECTRONIC systems - Abstract
Pressure can tune material's electronic properties and control its quantum state, making some systems present disconnected superconducting region as observed in iron chalcogenides and heavy fermion CeCu
2 Si2 . For CaC6 superconductor (Tc of 11.5 K), applying pressure first Tc increases and then suppresses and the superconductivity of this compound is eventually disappeared at about 18 GPa. Here, we report a theoretical finding of the re-emergence of superconductivity in heavily compressed CaC6 . The predicted phase III (space group Pmmn) with formation of carbon nanofoam is found to be stable at wide pressure range with a Tc up to 14.7 K at 78 GPa. Diamond-like carbon structure is adhered to the phase IV (Cmcm) for compressed CaC6 after 126 GPa, which has bad metallic behavior, indicating again departure from superconductivity. Re-emerged superconductivity in compressed CaC6 paves a new way to design new-type superconductor by inserting metal into nanoporous host lattice. [ABSTRACT FROM AUTHOR]- Published
- 2013
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15. Proteomic analysis of cisplatin resistance in human ovarian cancer using 2-DE method.
- Author
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Fengming Gong, Xingchen Peng, Zhi Zeng, Ming Yu, Yuwei Zhao, and Aiping Tong
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Platinum-based chemotherapy, such as cisplatin, is the primary treatment for human ovarian cancer. However, overcoming drug resistance has become an important issue in cancer chemotherapy. In this study, we performed 2-DE and ESI-Q-TOF MS/MS analysis to identify differential proteins expression between cisplatin-sensitive (A2780S) and cisplatin-resistant (A2780-CP) ovarian cancer cell lines. Of the 14 spots identified as differentially expressed (±over twofold, P < 0.05) between the two cell lines, ten spots (corresponding to ten unique proteins) were positively identified by ESI-Q-TOF MS/MS analysis. These proteins include capsid glycoprotein, fructose-bisphosphate aldolase C, heterogeneous nuclear ribonucleoproteins A2/B1, putative RNA-binding protein 3, Ran-specific GTPase-activating protein, ubiquitin carboxyl-terminal hydrolase isozyme L1, stathmin, ATPSH protein, chromobox protein homolog3 and phosphoglycerate kinase 1. The proteins identified in this study would be useful in revealing the mechanisms underlying cisplatin resistance and also provide some clues for further research. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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16. Different angiogenesis effect of mini-TyrRS/mini-TrpRS by systemic administration of modified siRNAs in rats with acute myocardial infarction.
- Author
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Rui Zeng, Yu-Cheng Chen, Zhi Zeng, Wei-Qiang Liu, Xiao-Xia Liu, Rui Liu, Ou Qiang, and Xian Li
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NEOVASCULARIZATION ,MYOCARDIAL infarction ,IMMUNOHISTOCHEMISTRY ,RATS ,LIGATURE (Surgery) - Abstract
We aimed to clarify the different angiogenesis effects of mini-tyrosyl-tRNA synthetase (TyrRS)/minitryptophanyl-tRNA synthetase (TrpRS) in rodent primates with acute myocardial infarction, by delivering small interfering RNAs (siRNAs) systemically in a liposomal formulation. Left coronary artery ligation was used to establish the model of acute myocardial infarction in rats; mini-TyrRS/mini-TrpRS-specific siRNAs were encapsulated in stable nucleic acid lipid particles (SNALP), and administered by intravenous injection to rats. Rats were divided into four experiment groups: sham operated group (no left anterior descending artery [LAD] occlusion); negative control group (LAD occlusion + saline injection); mock transfection group (LAD occlusion + mock transfected injection); experiment group (LAD occlusion + mini-TyrRS/mini-TrpRS-specific siRNAs injection). Silencing efficiency was assayed by Western blotting. To determine whether mini-TyrRS/mini-TrpRS affected the angiogenesis activity of rats with myocardial infarction, we measured the myocardial infarction size by TTC staining, and the capillary density using immunohistochemistry staining, to investigate the expression of factor VIII. The myocardial infarction size and the capillary density of mini-TyrRS-siRNA group were respectively 18.89% and 8.64/0.1 mm
2 1 month after ligation, while in the mini-TrpRS-siRNA group these values were 7.33% and 17.32/0.1 mm2 , significantly different compared with the mock transfection group (14.19%; 13.56/0.1 mm2 ) and negative control group (14.28%; 13.89/0.1 mm2 ), P < 0.05. There were no significant changes between the mock transfection group and the negative control group, P > 0.05. These results indicated that angiogenesis is either stimulated by mini-TyrRS or inhibited by mini-TrpRS in rat models with acute myocardial infarction. [ABSTRACT FROM AUTHOR]- Published
- 2010
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17. Aquaporin-1 expression and angiogenesis in rabbit chronic myocardial ischemia is decreased by acetazolamide.
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Xun Ran, Haoyu Wang, Yucheng Chen, Zhi Zeng, Qin Zhou, Rong Zheng, Jiayang Sun, Bing Wang, Xiaoyan Lv, Yujia Liang, Ke Zhang, and Weiqiang Liu
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AQUAPORINS ,NEOVASCULARIZATION ,LABORATORY rabbits ,ISCHEMIA ,ACETAZOLAMIDE - Abstract
Aquaporin-1 (AQP1) is a water channel protein expressed in endothelial and epithelial cells of many tissues, including the vasculature, where it serves to increase water permeability of the cell membrane. Prior studies have also reported that AQP1 plays a central role in tumor angiogenesis by promoting endothelial cell migration. To investigate whether AQP1 might also influence vascular angiogenesis in ischemic myocardium, the expression level of AQP1 for 21 days post myocardial infarction in rabbit hearts was observed. Aquaporin-1 mRNA and protein levels in day 3, and peaked on day 7 post surgery. This correlated well with the pattern of neovascularization and increased water content of infarct border tissue, and suggested that AQP1 may be involved in myocardial angiogenesis in response to ischemia injury. These AQP1-induced changes were tempered by acetazolamide, a carbonic anhydrase inhibitor, which acted by downregulating AQP1 expression. Acetazolamide treatment did not significantly affect the expression of vascular endothelial growth factor in the tissues studied. Our findings indicate a novel role for AQP1 in postnatal angiogenesis, which has implications in diverse pathophysiological conditions including wound healing, tumor metastasis, and organ regeneration. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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18. The Expression of a Recombinant cry1Ac Gene with Subtilisin-Like Protease CDEP2 Gene in Acrystalliferous Bacillus thuringiensis by Red/ET Homologous Recombination.
- Author
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Liqiu Xia, Zhi Zeng, Xuezhi Ding, and Fan Huang
- Subjects
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BACILLUS thuringiensis genetics , *ANTISENSE DNA , *PROTEOLYTIC enzymes , *POLYMERASE chain reaction , *DISEASE vectors , *PLASMIDS - Abstract
A novel cDNA encoding the subtilisin-like serine protease gene CDEP2 was isolated from Beauveria bassiana by reverse transcription polymerase chain reaction (RT-PCR). It contained an 1137 bp ORF that predicted a protein of 379 amino acids with M = 38863 Da and p I = 8.21. In an attempt to improve insecticidal activity, the CDEP2 gene and the cry1Ac gene from Bacillus thuringiensis were co-fused into the vector pHT315 as pHAc–CDEP2 plasmid by Red/ET homologous recombination. The co-fusion gene was attempted under the control of the native cry1Ac promoter. Plasmid pHAc–CDEP2 was electro-transformed into the B. thuringiensis subsp. kurstaki Cry−B. Analyzed by SDS-PAGE and Western blotting, the transformant Cry−B–pHAc–CDEP2 strain produced a 130 kDa Cry1Ac protein and 39 kDa CDEP2 protein. The 50% lethal concentration values (LC50) of Cry−B–pHAc–CDEP2 strain (8.5 μl/ml) to Helicoverpa armigera third instars larvae was clearly higher than the Cry−B–pHAc strain (16.7 μl/ml) at 72 h. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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19. Dual-rhodamine urea derivative, a novel chemidosimeter for Hg(II) and its application in imaging Hg(II) in living cells.
- Author
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Pin-xian Xi, Liang Huang, Heng Liu, Peng-fei Jia, Feng-juan Chen, Min Xu, and Zheng-zhi Zeng
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RHODAMINE B ,FLUORESCENCE spectroscopy ,HYDROGEN-ion concentration ,CATIONS ,MOLECULAR probes ,PHYSICAL & theoretical chemistry - Abstract
The synthesis and spectral properties of a chemidosimeter 1,4-di[2-(6-ethylamino-3-ethylimino-2,7-dimethyl-3H-xanthen-9-yl) benzoic acid (aminomethyl)-3-phenylthiourea] benzene ( 1) for Hg(II) ions are reported, and it has been demonstrated that 1 can be used as a fluorescent probe for monitoring Hg(II) ions in living cells. A highly sensitive fluorescent probe ( 1) was developed as a fluorescent and colorimetric chemodosimeter in dimethyl sulfoxide/methanol solution with a broad pH range (pH 5–10) and high selectivity toward Hg
2+ ions but no significant response toward other competitive cations. Furthermore, by means of confocal laser scanning microscopy experiments, it is demonstrated that 1 can be used as a fluorescent probe for monitoring Hg2+ in living cells.[Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]- Published
- 2009
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20. Synthesis, Characterization, Antioxidant Activity and DNA-Binding Studies of Three Rare Earth (III) Complexes with 1-(4-Aminoantipyrine)-3-tosylurea Ligand.
- Author
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Pin-xian Xi, Zhi-hong Xu, Xiao-hui Liu, Feng-juan Chen, Zheng-zhi Zeng, Xiao-wen Zhang, and Ying Liu
- Subjects
RARE earth metals ,COMPLEX compounds ,ANTIOXIDANTS ,ELECTROCHEMICAL analysis - Abstract
Abstract 1-(4-Aminoantipyrine)-3-tosylurea (H2L) and its three lanthanide (III) complexes, M(H2L)3 3NO3 [where M = Nd(III), Sm(III) and Eu(III)], have been synthesized and characterized. In addition, the DNA-binding properties of the three complexes have been investigated by UV–vis (ultraviolet and visible) absorption spectroscopy, fluorescence spectroscopy, circular dichroism (CD) spectroscopy, cyclic voltammetry, and viscosity measurements. Results suggest that the three complexes bind to DNA via a groove binding mode. Furthermore, the antioxidant activity (superoxide and hydroxyl radical) of the metal complexes was determined by using spectrophotometer methods in vitro. These complexes were found to possess potent antioxidant activity and be better than standard antioxidants like vitamin C and mannitol. Absorption spectra of the complex 3 inTris-HCl buffer upon addition of calf-thymus DNA. [complex]=1×10-5 M, [DNA]=(0-1) ×10-5 M. Arrow shows the absorbance changing upon increasing DNA concentrations. Inset: plots of [DNA]/(εa – εf) versus [DNA] for the titration of DNA with the complex. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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21. Protcomic analysis of cervical cancer cells treated with subcronylanilidc hydroxamic acid.
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Jianxiong He, Canhua Huang, Aiping Tong, Bin Chen, Zhi Zeng, Peng Zhang, Chunting Wang, and Yuquan Wei
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HYDROXAMIC acids ,HISTONE deacetylase ,PROTEIN analysis ,CERVICAL cancer treatment ,POLYACRYLAMIDE gel electrophoresis - Abstract
Suberonylanilide hydroxamic acid (SAHA) is an orally administered histone deacetylase inhibitor (HDACI) that has shown significant antitumour activity in a variety of tumour cells. To identify proteins involved in its antitumour activity, we utilized a proteomic approach to reveal protein expression changes in the human cervical cancer cell line HeLa following SAHA treatment. Protein expression profiles were analysed by 2-dimensional polyacrylamide gel electrophoresis (2-DE) and protein identification was performed on a MALDI-Q-TOF MS/MS instrument. As a result, a total of nine differentially expressed proteins were visualized by 2-DE and Coomassie brilliant blue (CBB) staining. Further, all the changed proteins were positively identified via mass spectrometry (MS)/MS analysis. Of these, PGAM1 was significantly downregulated in HeLa cells after treatment with SAHA. Moreover, PGAM1 has been proven to be downregulated in another cervical cancer cell line (CaSki) by western blot analysis. Together, using proteomic tools, we identified several differentially expressed proteins that underwent SAHA-induced apoptosis. These changed proteins may provide some clues to a better understanding of the molecular mechanisms underlying SAHA-induced apoptosis in cervical cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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22. Synthesis and characterization of a novel Anderson-type tungstotellurate decorated by transition metal complexes: [Na(H2O)3]2[{Cu(2,2′-bipy)2}2(TeW6O24)] · 4H2O
- Author
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Zhi-hong Xu, Pin-xian Xi, Feng-juan Chen, and Zheng-zhi Zeng
- Abstract
Abstract A novel organic–inorganic hybrid tungstotellurate [Na(H2O)3]2[{Cu(2,2′-bipy)2}2(TeW6O24)] · 4H2O, has been synthesized and characterized by elemental analyses, IR spectra, TG analyses, and single-crystal X-ray diffraction. The saturated Anderson-type polyoxoanions are covalently bonded with two [Cu(2,2′-bipy)2]2+, and linked by Na+ into an infinite one-dimensional chain. Furthermore, the three-dimensional supramolecular architectures are formed by π–π stacking interactions of the 2,2′-bipyridine groups between adjacent layers and the hydrogen-bonding interactions respectively. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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23. Synthesis, characterization, and DNA-binding properties of copper(II), cobalt(II), and nickel(II) complexes with salicylaldehyde 2-phenylquinoline-4-carboylhydrazone.
- Author
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Zhi-hong Xu, Pin-xian Xi, Feng-juan Chen, Xiao-hui Liu, and Zheng-zhi Zeng
- Abstract
Abstract  Salicylaldehyde 2-phenylquinoline-4-carboylhydrazone (H2L), and its novel copper(II), cobalt(II), and nickel(II) complexes MHL · Cl · nH2O [M=Cu n = 3 (1), M=Co n = 2 (2), M=Ni n = 3.5 (3)] have been synthesized and characterized by elemental analysis, molar conductivity, spectroscopic, and thermal analysis. The interaction of these complexes with calf thymus DNA was investigated by UV absorption spectroscopy, fluorescence spectroscopy, cyclic voltammetry, and viscosity measurements. The results suggest that these complexes bind to DNA via an intercalation binding mode and their affinity to DNA follows the order of 3 > 1> 2. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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24. Small interfering RNA knockdown of mini-TyrRS and mini-TrpRS effects angiogenesis in human umbilical vein endothelial cells in hypoxic culture.
- Author
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Rui Zeng, Yu-cheng Chen, Zhi Zeng, Rui Liu, Ou Qiang, Xiao-fei Jiang, Xiao-xia Liu, Xian Li, and Hao-yu Wang
- Abstract
Abstract Aim We studied the role of mini-TyrRS and mini-TrpRS in angiogenesis by using small interfering RNA-mediated mini-TyrRS/mini-TrpRS knockout in hypoxic culture of human umbilical vein endothelial cells. Methods SiRNA was used as the main method to inhibited the gene function. Silencing efficiency was assayed by real-time reverse transcription-polymerase chain reaction and western blotting. The angiogenic activity in vitro was evaluated by transwell migration assay and Matrigel-induced capillary tube formation in hypoxic culture. Cell proliferation was determined by crystal violet staining. Results The results showed that levels of the mini-TyrRS/mini-TrpRS gene and protein in mock transfection group and negative control group were higher, but noticeably decreased in experimental group. However, no significant difference was detected between mock transfection group and negative control group, but there was a statistically significant difference compared with experimental group. For mini-TyrRS-siRNA group, the cell migration, tube formation and the rate of cell proliferation were respectively inhibited by (47.4, 56.3, 65.4, 73.7%), (60.5, 69.1, 75.9, 83.6%) and (40.4, 56.2, 61.2, 68.0%). For mini-TrpRS-siRNA, were respectively increased by (18.0, 33.8, 45.1, 56.4%), (18.3, 31.2, 40.3, 45.7%) and (8.4, 26.4, 38.2, 46.6%). Conclusion These results indicated that angiogenesis is either stimulated by mini-TyrRS or inhibited by mini-TrpRS in matrigel models in hypoxic culture, raising the possibility that mini-TyrRS stimulates a common downstream signaling event. Thus, naturally occurring fragments of two proteins involved in translation, TyrRS and TrpRS, have opposing activity on endothelial cell angiogenesis in the matrigel assays. The opposing activities of the two tRNA synthetases suggest tight regulation of the balance between pro- and anti-angiogenic stimuli. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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25. Amended final-offer arbitration over an uncertain value: A comparison with CA and FOA.
- Author
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Deck, Cary, Farmer, Amy, and Dao-Zhi Zeng
- Subjects
ARBITRATION & award ,MEDIATION ,CONFLICT management ,CONCILIATION (Civil procedure) ,ORGANIZATIONAL justice - Abstract
Arbitration is increasingly employed to resolve disputes. Two arbitration mechanisms, conventional arbitration (CA) and final-offer arbitration (FOA) are commonly utilized, but previous theoretical and empirical research has found that they are unsatisfactory. Several alternative mechanisms have been proposed, but ultimately laboratory research has found that they do not offer an improvement. An exception is amended final-offer arbitration (AFOA), which not only has desirable theoretical properties but also has been demonstrated to outperform FOA in the laboratory. This study provides a direct laboratory comparison of AFOA with CA. Also, by utilizing an environment with an uncertain payoff to one of the parties, this study tests the robustness of AFOA’s performance relative to FOA. The results indicate that AFOA does outperform FOA, but that AFOA is only weakly better than CA. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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26. Three salicylaldehyde derivative Schiff base ZnII complexes: synthesis, DNA binding and hydroxyl radical scavenging capacity.
- Author
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Hui-Li Lu, Jian-Jun Liang, Zheng-Zhi Zeng, Pin-Xian Xi, Xiao-Hui Liu, Feng-Juan Chen, and Zhi-Hong Xu
- Abstract
Abstract  Three new Schiff base ligands N-(3-formyl-5-methylsalicylidene)-2-aminoethanol (H2L1), N-(3-hydroxylmethyl-5-methylsalicylidene)-2-aminoethanol (H3L2), 2,6-bis(o-carboxyphenyliminomethene)-4-methylphenol (H3L3) and their binuclear ZnII complexes [Zn2(HL1)2]Cl2 � 2H2O (ZnHL1), [Zn2(H2L2)2]Cl2 � H2O (ZnH2L2) and [Zn2(HL3)Cl2] � H2O (ZnHL3) were synthesized and characterized by 1H-NMR, elemental analysis, IR and molar conductivity. The results suggest, in every case, two Zn2 ions were bridged by phenolic OH group oxygen, forming a binuclear complex. The binding properties of these complexes to calf thymus DNA (ct-DNA) were investigated. Absorption and fluorescence spectra are together suggestive that both ZnHL1 and ZnHL3 interact with ct-DNA through intercalative mode, while ZnH2L2 interact with ct-DNA by non-intercalative interaction. Moreover, ZnHL3 can bind to ct-DNA more strongly than ZnHL1. These complexes also exhibited good scavenging activity on the hydroxyl radical (â¢OH), which are better than those of their corresponding ligands. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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27. Redispersion is different from dispersion: spatial economy of multiple industries.
- Author
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Dao-Zhi Zeng
- Subjects
MANUFACTURING industries ,TRANSPORTATION ,MANUFACTURING processes ,MONOPOLISTIC competition ,ECONOMIC geography ,FARM produce ,AGRICULTURE ,ECONOMIES of scale ,INDUSTRIAL costs - Abstract
In the literature of new economic geography, it is observed that the manufacturing sector disperses because of high transportation costs, agglomerates for intermediate transportation costs, and redisperses for low transportation costs. This paper examines a model with multiple manufacturing industries and finds that the redispersion process is different from the dispersion process. More precisely, there is at most one industry that disperses in the redispersion process while all industries disperse in the dispersion process. Furthermore, it is shown that the interaction of demand, increasing returns, and transportation costs is enough to derive a separating equilibrium where at least two industries agglomerate in different regions. [ABSTRACT FROM AUTHOR]
- Published
- 2006
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28. On the Emergence of Intra-industry Trade.
- Author
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Kikuchi, Toru, Shimomura, Koji, and Dao-Zhi Zeng
- Subjects
INTRA-industry trade ,STANDARDIZATION ,MONOPOLIES ,COMMERCE ,ECONOMIC competition - Abstract
This note explores the determinants of intra-industry trade by extending the standard Chamberlinian-Ricardian monopolistic competition trade model (e.g., Krugman, 1979) to have a continuum of industries (e.g., Dornbusch et al., 1977). It shows that the degree of cross-country technical differences among industries plays an important role as a determinant of trade within each industry. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
29. Mark-Choose-Cut Algorithms For Fair And Strongly Fair Division.
- Author
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Shishido, Harunor and Dao-Zhi Zeng
- Subjects
- *
PROBLEM solving , *ALGORITHM research , *DIVISION , *ARITHMETIC , *PARALLEL algorithms , *ALGEBRAIC fields - Abstract
This paper proposes a new criterion to evaluate algorithms for cake division, by the number of resulting pieces. Then, inspired by the idea of "cut-and-choose", we present "mark-choose-cut" algorithms for fair and strongly fair cake division problems. They are game-theoretic algorithms. The number of resulting pieces is bounded by 2 × 3n-2 + 1 and 4 × 3n-2 + 1, for fair and strongly fair division respectively. [ABSTRACT FROM AUTHOR]
- Published
- 1999
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30. Three new triterpenoids from Rubia schumanniana
- Author
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Jing Han, Guang-Zhi Zeng, Wen-Jun He, Xiao-Qiang Chen, Ning-Hua Tan, and Bin Kuang
- Subjects
Pharmacology ,Traditional medicine ,Chemistry ,Organic Chemistry ,Pharmacology toxicology ,Regular Article ,Plant Science ,Toxicology ,Biochemistry ,Rubia schumanniana ,Analytical Chemistry ,Triterpenoid ,Plant biochemistry ,Ic50 values ,cytotoxicity ,triterpenoid ,Food Science - Abstract
Three new triterpenoids, 3β-hydroxy-urs-30-p-Z-hydroxycinnamoyl-12-en-28-oic-acid (1), 3β-hydroxy-olean-30-p-Ehydroxycinnamoyl-12-en-28-oic-acid (2) and 3β,6α-dihydroxy-urs-14-en-12-one (3), together with seven known triterpenoids, were isolated from the roots of Rubia schumanniana. Their structures were established by means of spectroscopic analysis. All compounds were evaluated for cytotoxic activity, and compounds 2–6 showed cytotoxicity with the IC50 values of 10.75∼18.87 µg/mL. Electronic Supplementary Material Supplementary material is available for this article at 10.1007/s13659-012-0038-8 and is accessible for authorized users.
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31. Expression of AE1/p16 promoted degradation of AE2 in gastric cancer cells
- Author
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Jun Wu, Hong-Jun Fei, Guo-Hui Fu, Hua Tian, Xiao-Shu Jiang, Ling-Jun Song, Zhi Zeng, Ye Yang, Ting Wang, and Min Yan
- Subjects
0301 basic medicine ,AE1 ,AE2 ,Cancer Research ,Intracellular pH ,Immunoblotting ,Fluorescent Antibody Technique ,Mice, Nude ,p16 ,Gastrin ,03 medical and health sciences ,Mice ,0302 clinical medicine ,stomatognathic system ,Surgical oncology ,Stomach Neoplasms ,Anion Exchange Protein 1, Erythrocyte ,Cell Line, Tumor ,Gastrins ,medicine ,Genetics ,Gene silencing ,Animals ,Humans ,Immunoprecipitation ,Chloride-Bicarbonate Antiporters ,Cyclin-Dependent Kinase Inhibitor p16 ,Gene knockdown ,Mice, Inbred BALB C ,business.industry ,Cancer ,medicine.disease ,Molecular biology ,Xenograft Model Antitumor Assays ,stomatognathic diseases ,030104 developmental biology ,Membrane ,Oncology ,030220 oncology & carcinogenesis ,Cancer cell ,Immunology ,Female ,business ,Gastric cancer ,Research Article - Abstract
Background Human anion exchanger 1 and 2 (AE1 and AE2) mediate the exchange of Cl−/HCO3− across the plasma membrane and regulate intracellular pH (pHi). AE1 is specifically expressed on the surface of erythrocytes, while AE2 is widely expressed in most tissues, and is particularly abundant in parietal cells. Previous studies showed that an interaction between AE1 and p16 is a key event in gastric cancer (GC) progression, but the importance of AE2 in GC is unclear. Methods The relationship among AE1, AE2 and p16 in GC cells was characterized by molecular and cellular experiments. AE2 expression and pHi were measured after knockdown or forced expression of AE1 or p16 in GC cells. The effect of AE2 on GC growth and the correlation of AE2 expression with differentiation and prognosis of GC were also evaluated. The effect of gastrin on AE2 expression and GC growth was investigated in cellular experiments and mouse xenograft models. Results p16 binds to both AE1 and AE2 simultaneously. AE1 or p16 silencing elevated AE2 expression on the plasma membrane where it plays a role in pHi regulation and GC suppression. AE2 expression was decreased in GC tissue, and these decreased levels were correlated with poor differentiation and prognosis of GC. The low AE2 protein levels are due to rapid ubiquitin-mediated degradation that was facilitated in the presence of p16. Gastrin inhibited the growth of GC cells at least partially through up-regulation of AE2 expression. Conclusion AE1/p16 expression promoted AE2 degradation in GC cells. Gastrin is a potential candidate drug for targeted therapies for AE1- and p16-positive GC.
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32. Mental health status and work environment among workers in small- and medium-sized enterprises in Guangdong, China-a cross-sectional survey
- Author
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Liming Lu, Yan Guo, Wen Chen, Lu Han, Zhi Zeng, and Li Ling
- Subjects
Adult ,Male ,medicine.medical_specialty ,China ,Cross-sectional study ,Occupational Health Services ,Emigrants and Immigrants ,Occupational safety and health ,Psychological well-being ,Sex Factors ,Environmental health ,medicine ,Humans ,Workplace ,Small- and medium-sized enterprises (SMEs) ,business.industry ,Job demand-control-support (JDCS) model ,Public health ,Mental Disorders ,Age Factors ,Job demand-control (JDC) model ,Public Health, Environmental and Occupational Health ,Mental health ,WHO (five) well-being index ,Cross-Sectional Studies ,Logistic Models ,Chinese workers ,Marital status ,Female ,Biostatistics ,business ,Psychosocial ,Research Article - Abstract
Background Small- and medium-sized enterprises (SMEs) generate nearly 80% of the jobs in China, but the dangerous work environment often found in these enterprises poses a major concern for public health. Psychosocial pressure and mental health problems among the workers are also common in SMEs. However, mental health of workers in SMEs is largely neglected in occupational health research and practice in China. The purpose of this study is to assess mental health of the workers and to explore the associations between physical and psychosocial work environment and workers’ mental health in SMEs in South China. Methods Data were collected in 2012 through a cross-sectional survey among 1200 workers working in small- and medium-sized enterprises (SMEs) in Guangdong, China. Mental health was measured by psychological well-being in the current study. Job Demand-Control-Support (JDCS) model was used as a theoretical framework to examine the psychosocial factors associated with workers’ psychological well-being. Data were analyzed using SPSS 20.0 and analysis was performed using bivariate analyses and multivariate logistic regression. Results About three in ten workers (35.3%) in the sample had poor psychological well-being. Those who were men, younger in age, or migrant workers had worse psychological outcome in bivariate analyses. After controlling for individual variables (gender, age, marital status, and household registration), we found that longer weekly work hours (OR = 1.30, 95% CI: 1.13 ~ 1.50), more exposure to hazardous work environment (OR = 1.26, 95% CI: 1.10 ~ 1.44), higher job demands (OR = 1.29, 95% CI: 1.12 ~ 1.49), and lower job autonomy (OR = 0.70, 95% CI: 0.60 ~ 0.81) were significant associated with worse psychological well-being. The results were consistent with predictions of the JDCS model. Conclusions The results indicate that the JDCS model is a useful framework in predicting psychological well-being among Chinese workers in SMEs. Future mental health promotion should focus on young migrant male workers as they appear to be most vulnerable in their psychological well-being. Both physical and psychosocial aspects of the work environment should be taken into account in policy making to prevent mental disorder and promote psychological well-being among workers in SMEs.
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33. Research on a nonlinear hybrid optimal PSO microseismic positioning method.
- Author
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Xiao, Yang, Liu, Wei-jian, Wang, Hao-nan, Hou, Meng-jie, Dong, Sen-sen, and Zhang, Zhi-zeng
- Abstract
Impact ground pressure events occur frequently in coal mining processes, significantly affecting the personal safety of construction workers. Real-time microseismic monitoring of coal rock body rupture information can provide early warnings, and the seismic source location method is an essential indicator for evaluating a microseismic monitoring system. This paper proposes a nonlinear hybrid optimal particle swarm optimisation (PSO) microseismic positioning method based on this technique. The method first improves the PSO algorithm by using the global search performance of this method to quickly find a feasible solution and provide a better initial solution for the subsequent solution of the nonlinear optimal microseismic positioning method. This approach effectively prevents the problem of the microseismic positioning method falling into a local optimum because of an over-reliance on the initial value. In addition, the nonlinear optimal microseismic positioning method further narrows the localisation error based on the PSO algorithm. A simulation test demonstrates that the new method has a good positioning effect, and engineering application examples also show that the proposed method has high accuracy and strong positioning stability. The new method is better than the separate positioning method, both overall and in three directions, making it more suitable for solving the microseismic positioning problem. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
34. Formation of Nanofoam carbon and re-emergence of Superconductivity in compressed CaC6.
- Author
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Yan-Ling Li, Wei Luo, Xiao-Jia Chen, Zhi Zeng, Hai-Qing Lin, and Ahuja, Rajeev
- Subjects
- *
SUPERCONDUCTIVITY , *ELECTRIC conductivity , *SUPERFLUIDITY , *CRYOELECTRONICS , *ELECTRONIC systems - Abstract
Pressure can tune material's electronic properties and control its quantum state, making some systems present disconnected superconducting region as observed in iron chalcogenides and heavy fermion CeCu2Si2. For CaC6 superconductor (Tc of 11.5 K), applying pressure first Tc increases and then suppresses and the superconductivity of this compound is eventually disappeared at about 18 GPa. Here, we report a theoretical finding of the re-emergence of superconductivity in heavily compressed CaC6. The predicted phase III (space group Pmmn) with formation of carbon nanofoam is found to be stable at wide pressure range with a Tc up to 14.7 K at 78 GPa. Diamond-like carbon structure is adhered to the phase IV (Cmcm) for compressed CaC6 after 126 GPa, which has bad metallic behavior, indicating again departure from superconductivity. Re-emerged superconductivity in compressed CaC6 paves a new way to design new-type superconductor by inserting metal into nanoporous host lattice. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
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