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As a typical inland river basin in China, the Shiyang River Basin is characterized by its special mountain-basin structure. The ecological health in the basin is related to the sustainable development of the economy and society. At present, there are few studies on net primary productivity (NPP) in the Shiyang River Basin, and the existing analysis of the relationship between NPP and climatic factors is lacking. The upper mountainous area and the middle and lower oasis areas in the Shiyang River Basin were selected as the study area. The NPP of the study area was estimated using the Thornthwaite Memorial Model. The spatial and temporal characteristics of NPP were analyzed by Sen’s slope method. Based on the sensitivity analysis, the correlation of the main climate factors to NPP was estimated. According to the aforementioned work, the variation trend of the future NPP was predicted. The results showed that NPP in the study area increased from 1981 to 2015 with the increase in temperature and precipitation. The spatial heterogeneity of the change trend of NPP was not significant, but the spatial heterogeneity of the rangeability was strong. The NPP was highly sensitive to precipitation, relative humidity and net solar radiation. By integrating the changes in climatic elements, the temperature, precipitation and relative humidity contributed the main parts of the change in NPP. The NPP is predicted to increase by 4.9–8.1% by 2050 according to the amplitude of climate change over the past 35 yrs. [ABSTRACT FROM AUTHOR]

Di-2-ethylhexyl phthalate (DEHP) which belongs to phthalatic-acid esters, is a kind of harmful, global environmental pollutants. It is a known endocrine disrupting chemical and male reproductive toxicant. However, the mechanism by which DEHP exposure result in male reproductive toxicity is still unclear. To elucidate the productive toxicity mechanism of DEHP, we attemptted to investigate oxidative stress, apoptotic effects, mRNA and protein expression of apoptosis-associated genes including FasL, caspase-3, and caspase-8 in GC-2spd (mouse spermatogenic cells). The results showed that, with the increase of DEHP concentration, cell apoptosis rate increased; the activities of relation index of oxidative stress such as malondialdehyde (MDA), superoxide dismutase (SOD) and glutatione peroxidase (GSH-PX) changed significantly; the mRNA and protein expression levels of FasL, caspase-3, -8, altered obviously. These results suggested that DEHP could induce apoptosis of GC-2spd cells through oxidative stress and FasL-dependent pathway. [ABSTRACT FROM AUTHOR]