1. Introduction and scope of monograph
- Author
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Teresa Gessner and Peter K. Gessner
- Subjects
chemistry.chemical_compound ,chemistry ,International Nonproprietary Name ,Disulfide bond ,Dithiocarb ,Medicinal chemistry ,Sodium diethyldithiocarbamate ,Sodium salt - Abstract
Disulfiram (DSSD), widely known under the trade name, Antabuse®, is a symmetrical disulfide which can be reduced to two molecules of the thiol (DSH) which, at physiological pH is better than 99% ionized to diethyldithiocarbamate and so referred to in this book. The sodium salt of diethydithiocarbamic acid is available both in an anhydrous form and as a trihydrate. It was earlier given the appellation dithiocarb (West and Sunderman, 1958; Sunderman and Sunderman, 1958; Merck Index, 1968). More recently it has been assigned the International Nonproprietary Name ditiocarb sodium (Merck Index, 1989; USAN, 1990).
- Published
- 1992
- Full Text
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