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Background: While there are multiple safe and effective agents for COVID-19 treatment, their impact in inflammatory bowel disease (IBD) remains uncertain., Aims: Our objective was to assess the effects of these therapies on both IBD and COVID outcomes., Methods: A single-center retrospective study of adult patients with IBD who contracted COVID-19 between 12/2020 and 11/2022 was performed. Patients were stratified by COVID-19 treatment (antivirals and/or intravenous antibodies) vs no therapy. The primary outcome was the development of severe COVID-19 infection, defined by need for supplemental oxygen, corticosteroids and/or antibiotics, or hospitalization. Secondary outcomes included rates of withholding advanced IBD therapy (defined as biologic agents or small molecules) and of post-COVID-19 IBD flare., Results: Of 127 patients with COVID-19 infection, 70% were on advanced therapies, 35% received COVID-19 treatment, and 15% developed severe COVID-19. Those treated for COVID-19 were more likely to be on corticosteroids [odds ratio (OR) 4.61, 95% confidence interval (CI) 1.72-12.39, p = 0.002] or advanced IBD therapies (OR 2.78, 95% CI 1.04-7.43, p = 0.041). After adjusting for age, race, sex, corticosteroid use, obesity, COVID-19 vaccination status, and severe COVID-19 infection, those treated for COVID-19 were more likely to have IBD therapy held (OR 6.95, 95% CI 1.72-28.15, p = 0.007). There was no significant difference in rates of post-COVID-19 IBD flares or severe COVID-19 infection. There were no COVID-related deaths., Conclusions: Patients with IBD on advanced therapies were frequently treated for acute COVID-19. Although COVID-19 treatment was associated with temporary withholding of IBD therapy, it did not result in increased IBD flares., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Background: Inflammatory bowel diseases (IBD) and the therapies used to treat these conditions can lead to preventable complications. In 2011, AGA developed the Adult IBD Physician Performance Measures Set to improve accountability and performance management in IBD care; however, compliance remains poor., Aim: The aim of this study is to assess for an improvement in provider compliance with the recommended outpatient preventive care measures in our VA IBD patients after July 2014 following the implementation of a health maintenance template in the Computerized Patient Record system (CPRS)., Methods: We conducted a single-center, retrospective chart review of 139 IBD patients with at least one visit before and after the implementation of the health maintenance template through November 2016. We collected demographic data, immunosuppressive medication use, and recommendations for preventive care. For each variable analyzed, we included those patients where the preventive care measure was indicated based on age, gender, and/or medication use. The McNemar's test for paired nominal data was used to assess the significant difference in recommendation rate, pre- versus post-template implementation. A p value of < 0.05 was considered significant., Results: We included 139 patients (46% with Crohn's disease, 53% with ulcerative colitis, 1% with indeterminate colitis) in the analysis. Seventy-eight (56%) patients were on immunosuppressants. All preventive care measures significantly improved after implementation of the CPRS template except for HPV vaccination., Conclusions: Implementing a health maintenance template in outpatient GI clinic notes significantly improved provider documentation of the recommended outpatient preventive care in our VA IBD population.