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Your search keyword '"Alba Redo Riveiro"' showing total 1 results
Start Over Author "Alba Redo Riveiro" Publisher springer science and business media llc
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1. Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics

Author

Michaela Mrugala Rothová, Alexander Valentin Nielsen, Martin Proks, Yan Fung Wong, Alba Redo Riveiro, Madeleine Linneberg-Agerholm, Eyal David, Ido Amit, Ala Trusina, and Joshua Mark Brickman

Subjects
Mice, Pregnancy, Endoderm, Animals, Gene Expression Regulation, Developmental, Cell Differentiation, Female, Cell Biology, Transcriptome, Embryonic Stem Cells, Germ Layers
Abstract

High-resolution maps of embryonic development suggest that acquisition of cell identity is not limited to canonical germ layers but proceeds via alternative routes. Despite evidence that visceral organs are formed via embryonic and extra-embryonic trajectories, the production of organ-specific cell types in vitro focuses on the embryonic one. Here we resolve these differentiation routes using massively parallel single-cell RNA sequencing to generate datasets from FOXA2

Published
2022
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