11 results on '"Bill S. Majdalany"'
Search Results
2. Use of Metformin and Survival in Patients with Hepatocellular Carcinoma (HCC) Undergoing Liver Directed Therapy: Analysis of a Nationwide Cancer Registry
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Kumar Mukherjee, Mohammad Elsayed, Eshani Choksi, Mohammed F. Loya, Richard Duszak, Mehmet Akce, Bill S. Majdalany, Zachary L. Bercu, Mircea Cristescu, and Nima Kokabi
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Radiology, Nuclear Medicine and imaging ,Cardiology and Cardiovascular Medicine - Published
- 2023
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3. Collapse of inferior vena cava during complex filter retrieval with consequent intra-procedural systemic hypotension and bradycardia: a case report
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Tushar Garg, Izzet Altun, Bill S. Majdalany, and Nariman Nezami
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Radiology, Nuclear Medicine and imaging ,Cardiology and Cardiovascular Medicine - Abstract
Background Prolonged dwelling time of inferior vena cava (IVC) filters has been shown to increase the need for the use of complex IVC filter retrieval techniques. In this report, we describe a case of complex retrieval of an IVC filter with prolonged dwelling time, which was temporarily accompanied by severe bradycardia and hypotension. Case presentation Fifty-nine-year-old male patient past medical history of morbid obesity, atrial fibrillation status post-ablation, obstructive sleep apnea, and end-stage renal disease presented for IVC filter retrieval 16 years after placement. When the IVC filter was covered by sheaths, and the IVC was temporarily collapsed and occluded, the patient developed severe bradycardia and hypotension without compensatory tachycardia. Contrast injection through the common femoral vein sheath showed complete occlusion of IVC while the IVC filter was covered by both sheaths, likely due to the embedment of the IVC filter in the wall by extensive fibrinous tissues. IVC filter was successfully retrieved, and the blood pressure and heart rate were improved immediately afterward. A large non-occlusive IVC thrombus was identified on the final venogram, which was aspirated using a mechanical thrombectomy device. Conclusion Complex retrieval of IVC filters with prolonged dwelled time can result in acute severe bradycardia and hypotension due to vasovagal reaction, acute collapse, and occlusion of IVC in the setting of IVC filter embedment in the wall by extensive fibrinous tissues.
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- 2023
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4. Evaluation of Medium-Term Efficacy of Y90 Radiation Segmentectomy vs Percutaneous Microwave Ablation in Patients with Solitary Surgically Unresectable < 4 cm Hepatocellular Carcinoma: A Propensity Score Matched Study
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Nima Kokabi, Bill S. Majdalany, Bernard Cheng, Alexander Villalobos, Joseph F. Magliocca, M. Cristescu, Minzhi Xing, William Wagstaff, Marty T. Sellers, Linzi Arndt, Joel P. Wedd, Zachary L. Bercu, Anand D. Shah, and R. Ermentrout
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medicine.medical_specialty ,Percutaneous ,business.industry ,Microwave ablation ,medicine.disease ,Gastroenterology ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Hepatocellular carcinoma ,Toxicity ,Propensity score matching ,medicine ,Population study ,Radiology, Nuclear Medicine and imaging ,In patient ,Progression-free survival ,Cardiology and Cardiovascular Medicine ,business - Abstract
To evaluate the efficacy and safety of Y90 radiation segmentectomy (RS) vs. percutaneous microwave ablation (MWA) in patients with solitary HCC ≤ 4 cm. From 2014 to 2017, 68 consecutive treatment naive patients were included (34 per treatment arm). Chi-square and t-test were used to evaluate differences in baseline demographics between groups. Objective response was evaluated using mRECIST and toxicity using CTCAE. Overall survival (OS) and progression free survival (PFS) in the targeted tumor and the remainder of liver from initial treatment was calculated using Kaplan–Meier estimation. Propensity score matching was then performed with n = 24 patients matched in each group. Similar outcome analysis was then pre-formed. In the overall study population, both groups had similar baseline characteristics with the exception of larger lesions in the RS group. There was no difference in toxicity, objective tumor response, OS and non-target liver PFS between the MWA and RS group (p’s > 0.05). In the matched cohort, the objective tumor response was 82.6% in MWA vs. 90.9%% in RS (p = 0.548). The mean OS in the MWA group (44.3 months) vs RS (59.0 months; p = 0.203). The targeted tumor mean PFS for the MWA groups was 38.6 months vs. 57.8 months in RS group (p = 0.005). There was no difference overall PFS and toxicity between the 2 matched groups. Our data suggest Y90 RS achieves similar tumor response and OS with a similar safety compared to MWA in the management of HCC lesions ≤ 4 cm. Additionally, targeted tumor PFS appears to be prolonged in the RS group with similar non-target liver PFS between RS and MWA group.
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- 2020
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5. The resuscitative endovascular balloon occlusion of aorta (REBOA) device—what radiologists need to know
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Nima Kokabi, Adam Prater, Sean R. Dariushnia, Nariman Nezami, Laura K. Findeiss, Linzi Arndt, Danial Mir, Bill S. Majdalany, Johnathan Nguyen, and Derek L. West
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Aorta ,medicine.medical_specialty ,Thoracic Injuries ,business.industry ,medicine.medical_treatment ,General surgery ,Endovascular Procedures ,Aorta, Thoracic ,030208 emergency & critical care medicine ,Balloon Occlusion ,Shock, Hemorrhagic ,030218 nuclear medicine & medical imaging ,Food and drug administration ,03 medical and health sciences ,0302 clinical medicine ,Balloon occlusion ,medicine.artery ,Emergency Medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Thoracotomy ,business - Abstract
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a novel device approved by the Food and Drug administration (FDA) in 2017 as an alternative to resuscitative emergent thoracotomy (RET). Due to advancements in placement of REBOA, including newly validated placement using anatomic landmarks, REBOA is now widely used by interventional radiologists and emergency physicians in acute subdiaphragmatic hemorrhage. Increased use of REBOA necessitates that radiologists are familiar with verification of proper REBOA placement to minimize complications. This review describes the REBOA device, indications, placement, and complications, summarizing the current available literature.
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- 2019
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6. Radiofrequency Wire Recanalization of Chronically Occluded Venous Stents: A Retrospective, Single-Center Experience in 15 Patients
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Natosha Monfore, Bill S. Majdalany, Minhaj S. Khaja, and David M. Williams
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Adult ,Male ,medicine.medical_specialty ,Single Center ,030218 nuclear medicine & medical imaging ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Blunt ,Superior vena cava ,Occlusion ,Coagulopathy ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,Retrospective Studies ,Radiofrequency Ablation ,business.industry ,Graft Occlusion, Vascular ,Equipment Design ,Phlebography ,Middle Aged ,medicine.disease ,Surgery ,Dialysis fistula ,Venous thrombosis ,Treatment Outcome ,Female ,Stents ,Cardiology and Cardiovascular Medicine ,Complication ,business - Abstract
Chronically occluded venous stents may be difficult to salvage, necessitating multiple approaches and adjunctive techniques. Radiofrequency wires have been used to cross chronic obstructions in a variety of settings. Herein, radiofrequency wire recanalization (RFWR) of chronically occluded venous stents is presented. Fifteen patients (8 males; 7 females) aged 23–74 years (median 42 years) underwent prior venous stenting in the setting of venous occlusions. Seven had an underlying coagulopathy, three had May–Thurner syndrome, three had provoked deep venous thrombosis, one had a dialysis fistula, and one had pacer leads in situ. All indwelling venous stents were chronically occluded and symptomatic. Out of 15 patients, 13 (87%) had iliocaval venous stents, while two (13%) had superior vena cava and/or upper extremity venous stents. After failing conventional and blunt recanalization techniques, RFWR was performed to traverse the chronic occlusions. Technical success and complications were recorded. Fifteen patients underwent 19 procedures. Twelve patients underwent one procedure, two patients had two procedures, and one patient had three procedures. RFWR alone was used in 12/19 (63%) procedures, while 7/19 (37%) required adjunctive sharp recanalization techniques. Technical success or crossing of the occlusion with flow restoration through the occluded segments was achieved in 17/19 (89%). One major and one minor complication occurred. Radiofrequency wire recanalization is an effective adjunct to revise chronically occluded venous stents, potentially increasing procedural success in challenging cases.
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- 2018
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7. Pediatric lymphangiography, thoracic duct embolization and thoracic duct disruption: a single-institution experience in 11 children with chylothorax
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Minhaj S. Khaja, Jeffrey Forris Beecham Chick, Wael A. Saad, Kyle J. Cooper, Ravi N. Srinivasa, and Bill S. Majdalany
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Male ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Radiography, Interventional ,Chylothorax ,Thoracic duct ,Thoracic Duct ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Embolization ,Child ,Retrospective Studies ,Neuroradiology ,Congenital Chylothorax ,medicine.diagnostic_test ,business.industry ,Traumatic Chylothorax ,Infant, Newborn ,Infant ,Lymphography ,Interventional radiology ,medicine.disease ,Embolization, Therapeutic ,Treatment Outcome ,medicine.anatomical_structure ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Chylopericardium ,Female ,Radiology ,business - Abstract
Interventional radiology treatment of chylothorax is well described in adults, with high technical and clinical success that decreases patient morbidity and mortality. However there is limited experience in children. To report the technical and clinical success of lymphangiography, thoracic duct embolization and thoracic duct disruption in the pediatric population. We studied 11 pediatric patients (7 boys, 4 girls; median weight 6.0 kg) who underwent lymphangiography and thoracic duct embolization from November 2015 to May 2017. All 11 (100%) children presented with chylothorax, with 1 (9%) having concomitant chylous ascites and 1 (9%) having concomitant chylopericardium. Ten (91%) children had traumatic chylothorax and one (9%) had congenital chylothorax. We recorded technical success, clinical success and complications. Twelve procedures were completed in 11 children. Bilateral intranodal lymphangiography was technically successful in all (100%) patients. Central lymphatics were visualized in eight (67%) procedures. Access to central lymphatics was attempted in eight procedures and successful in five (63%). In three (37%) of the eight procedures, disruption was performed when the central lymphatics could not be accessed. Clinical success was achieved in 7/11 (64%) children. Three minor complications were reported. No major complications were encountered. Lymphangiography, thoracic duct embolization and thoracic duct disruption are successful interventional strategies in children with chylothorax and should be considered as viable treatment options at any age.
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- 2017
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8. Fluoroscopic Targeting of Wallstents and Amplatzer Vascular Plugs in Sharp Recanalization of Chronic Venous Occlusions
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David M. Williams, Ari D. Schuman, Wael E. Saad, Minhaj S. Khaja, Jeffrey Forris Beecham Chick, Bill S. Majdalany, and Kyle J. Cooper
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Adult ,Male ,medicine.medical_specialty ,Vena Cava, Superior ,Septal Occluder Device ,Vascular anatomy ,Patient demographics ,Technical success ,Vena Cava, Inferior ,Vascular plug ,030204 cardiovascular system & hematology ,030218 nuclear medicine & medical imaging ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Occlusion ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Vascular Diseases ,Aged ,Retrospective Studies ,Aged, 80 and over ,business.industry ,Middle Aged ,Treatment Outcome ,Fluoroscopy ,Chronic Disease ,Female ,Stents ,Radiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Sharp recanalization of chronic venous occlusions is usually performed with targeting of wire-capture devices like loop snares or balloons. We describe sharp recanalization of chronic venous occlusions using self-expanding stents and vascular plugs. We retrospectively reviewed all sharp venous recanalization procedures performed over an 11-month period and found Wallstent and Amplatzer vascular plug (AVP) targeting was performed in 16 patients. Patient demographics, occlusion site, targeting device, technical success of the targeting, and overall procedural success were recorded. Technical success was achieved in twelve (86%) Wallstent and two (67%) AVP deployments. Procedural success was achieved in 15 (94%). Three minor complications occurred. Wallstent and AVP targeting may be a useful technique when performing sharp recanalization for chronic venous occlusions. These devices expand the target space and present the same cross section viewed from any angle and can directly capture and extract the wire, features helpful in regions with crowded vascular anatomy.
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- 2017
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9. Prone Transradial Catheterization for Combined Single-Session Transarterial Embolization and Percutaneous Posterior Approach Cryoablation of Solid Neoplasms
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Casey Branach, Ravi N. Srinivasa, Minhaj S. Khaja, Wael A. Saad, Douglas A. Murrey, Bill S. Majdalany, J. Matthew Meadows, Kyle J. Cooper, Matthew L. Osher, and Jeffrey Forris Beecham Chick
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Adult ,Male ,medicine.medical_specialty ,Supine position ,Percutaneous ,Computed Tomography Angiography ,medicine.medical_treatment ,Operative Time ,Catheter ablation ,030204 cardiovascular system & hematology ,Cryosurgery ,030218 nuclear medicine & medical imaging ,Transradial catheterization ,03 medical and health sciences ,0302 clinical medicine ,Neoplasms ,Prone Position ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,Computed tomography angiography ,medicine.diagnostic_test ,business.industry ,Interventional radiology ,Cryoablation ,Equipment Design ,Middle Aged ,Combined Modality Therapy ,Embolization, Therapeutic ,Surgery ,Survival Rate ,Prone position ,Treatment Outcome ,Radial Artery ,Catheter Ablation ,Female ,Radiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Transradial access (TRA) has been associated with improved post-procedure hemostasis and patient satisfaction, and decreased hemorrhagic complications, sedation requirements, recovery times, and procedure-related costs when compared with traditional transfemoral catheterization. Supine TRA has been described for the treatment of myocardial infarctions, aortoiliac and femoropopliteal stenoses, and a variety of neoplasms. This original research describes prone transradial catheterization to facilitate combined single-session transarterial embolization and percutaneous cryoablation of solid neoplasms from a posterior approach without repositioning. Prone TRA access, transarterial embolization, and percutaneous cryoablation were successful in all cases described. Mean procedure time was 210 min (range: 140-250 min). One minor complication, transient bacteremia which responded to antibiotics, was reported. No major complications occurred.
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- 2016
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10. Radiofrequency Wire Recanalization of Chronically Thrombosed TIPS
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Bill S. Majdalany, Wael E. Saad, Eric D. Elliott, A. James Hanje, and Anthony Michaels
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Male ,medicine.medical_specialty ,Guide wires ,Catheterization ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Upper Extremity Deep Vein Thrombosis ,Cardiac interventions ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,business.industry ,Angiography, Digital Subtraction ,Equipment Design ,Middle Aged ,Surgery ,Treatment Outcome ,Venous thromboses ,Catheter Ablation ,030211 gastroenterology & hepatology ,Radiology ,Portasystemic Shunt, Transjugular Intrahepatic ,Cardiology and Cardiovascular Medicine ,business - Abstract
Radiofrequency (RF) guide wires have been applied to cardiac interventions, recanalization of central venous thromboses, and to cross biliary occlusions. Herein, the use of a RF wire technique to revise chronically occluded transjugular intrahepatic portosystemic shunts (TIPS) is described. In both cases, conventional TIPS revision techniques failed to revise the chronically thrombosed TIPS. RF wire recanalization was successfully performed through each of the chronically thrombosed TIPS, demonstrating initial safety and feasibility in this application.
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- 2016
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11. Impact of 90Y PET gradient-based tumor segmentation on voxel-level dosimetry in liver radioembolization
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Peter L. Roberson, Ravi N. Srinivasa, Kelly C. Younge, Ravi K. Kaza, Matthew J. Schipper, Theresa Devasia, Bill S. Majdalany, Yuni K. Dewaraja, Dawn Owen, Kyle C. Cuneo, and Justin Mikell
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lcsh:Medical physics. Medical radiology. Nuclear medicine ,Tumor segmentation ,lcsh:R895-920 ,Concordance ,Biomedical Engineering ,computer.software_genre ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,symbols.namesake ,0302 clinical medicine ,Voxel ,Dosimetry ,Medicine ,Radiology, Nuclear Medicine and imaging ,Segmentation ,Radioembolization ,90Y ,Instrumentation ,Radiation ,Auto-segmentation ,business.industry ,90Y PET ,Pearson product-moment correlation coefficient ,Concordance correlation coefficient ,030220 oncology & carcinogenesis ,Absorbed dose ,symbols ,Nuclear medicine ,business ,computer - Abstract
Background The purpose was to validate 90Y PET gradient-based tumor segmentation in phantoms and to evaluate the impact of the segmentation method on reported tumor absorbed dose (AD) and biological effective dose (BED) in 90Y microsphere radioembolization (RE) patients. A semi-automated gradient-based method was applied to phantoms and patient tumors on the 90Y PET with the initial bounding volume for gradient detection determined from a registered diagnostic CT or MR; this PET-based segmentation (PS) was compared with radiologist-defined morphologic segmentation (MS) on CT or MRI. AD and BED volume histogram metrics (D90, D70, mean) were calculated using both segmentations and concordance/correlations were investigated. Spatial concordance was assessed using Dice similarity coefficient (DSC) and mean distance to agreement (MDA). PS was repeated to assess intra-observer variability. Results In phantoms, PS demonstrated high accuracy in lesion volumes (within 15%), AD metrics (within 11%), high spatial concordance relative to morphologic segmentation (DSC > 0.86 and MDA 0.99, MDA
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- 2018
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