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Start Over Author "Clayton M. Carey" Publisher springer science and business media llc
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1. CRISPR Rube Goldberg machines for visualizing cell lineage

Author

Clayton M. Carey and James A. Gagnon

Subjects
0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, General Neuroscience, CRISPR, Cell lineage, Computational biology, Biology, Stem cell, Neuroscience, 030217 neurology & neurosurgery, Sequence (medicine)
Abstract

A new technique developed by Garcia-Marques and colleagues uses CRISPR–Cas9 editing to activate an ordered sequence of fluorescent markers in stem cells and their progeny. These tools represent a new way to probe the spatial and temporal patterns of cell lineage progression.

Published
2020

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