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29 results on '"Cocco, E."'

1. Pregnancy effect on disease activity in women with multiple sclerosis treated with cladribine

Author

Signoriello, E., primary, Foschi, M., additional, Lanzillo, R., additional, Frau, J., additional, Cocco, E., additional, Borriello, G., additional, Ianniello, A., additional, Trotta, M., additional, Landi, D., additional, Maniscalco, G. T., additional, Ruscica, F., additional, Toscano, S., additional, Patti, F., additional, Zanghì, A., additional, D’Amico, E., additional, Fantozzi, R., additional, Centonze, D., additional, Lus, G., additional, and Bonavita, S., additional

Published
2024
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2. Factors interfering with parenthood decision-making in an Italian sample of people with multiple sclerosis: an exploratory online survey

Author

Lavorgna, L., primary, Esposito, S., additional, Lanzillo, R., additional, Sparaco, M., additional, Ippolito, D., additional, Cocco, E., additional, Fenu, G., additional, Borriello, G., additional, De Mercanti, S., additional, Frau, J., additional, Capuano, R., additional, Trojsi, F., additional, Rosa, L., additional, Clerico, M., additional, Laroni, A., additional, Morra, V. Brescia, additional, Tedeschi, G., additional, and Bonavita, S., additional

Published
2019
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6. Cerebrospinal fluid findings in Devic?s neuromyelitis optica

Author

Zaffaroni, M, Trojano, M, Paolicelli, D, Capra, R, Salvi, F, Pastorelli, F, Marrosu, G, Cocco, E, Patti, Francesco, Tola, R, Caniatti, L, Amato, Mp, Ghezzi, A, Mancardi, Gl, Murialdo, A, Roccatagliata, L, Milanese, C, La Mantia, L, Comi, G, Martinelli, V, Filippi, M, Merelli, E, Sola, P, Bergamaschi, R, Tonietti, S, Gallo, P, Perini, P, and Bertolotto, A.

Subjects
Adult, Male, medicine.medical_specialty, Pathology, Neurology, Adolescent, Immunoglobulins, Lymphocytosis, Dermatology, Spinal Puncture, Diagnosis, Differential, White matter, Cerebrospinal fluid, medicine, Humans, Child, Pleocytosis, Aged, Neuromyelitis optica, medicine.diagnostic_test, business.industry, Lumbar puncture, Multiple sclerosis, Neuromyelitis Optica, General Medicine, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Psychiatry and Mental health, medicine.anatomical_structure, Child, Preschool, Female, Neurology (clinical), Differential diagnosis, business
Abstract

Relapsing Devic's neuromyelitis optica (DNO) may be clinically undistinguishable from multiple sclerosis (MS), thus the differential diagnosis relies mainly on neuroimaging and cerebrospinal fluid (CSF) findings. We studied CSF samples from 44 patients with DNO submitted to at least one lumbar puncture. Pleocytosis, IgG synthesis and blood brain barrier damage were the most frequent abnormalities, pleocytosis being very suggestive of DNO in patients fulfilling clinical and MRI diagnostic criteria. Pleocytosis > or =50 cells/mm3 is more frequent in the active phases of the disease. Oligoclonal bands (OBs) should be re-considered within the diagnostic criteria of DNO for possible variations in time: at variance with MS they may also disappear. Thus, more than one CSF examination should be done in the presence of suspected DNO, preferably in different disease phases. Although uncommon, OBs do not exclude DNO if optic nerve and spinal cord are the only sites of white matter damage, provided that cerebral MRI is normal at onset and during follow up.

Published
2004

9. Progressive multiple sclerosis and mood disorders

Author

Lorefice, Lorena, primary, Fenu, G., additional, Trincas, G., additional, Moro, M. F., additional, Frau, J., additional, Coghe, G. C., additional, Cocco, E., additional, Marrosu, M. G., additional, and Carta, M. G., additional

Published
2015
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11. Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo

Author

Schwab, C L, primary, Bellone, S, additional, English, D P, additional, Roque, D M, additional, Lopez, S, additional, Cocco, E, additional, Nicoletti, R, additional, Bortolomai, I, additional, Bonazzoli, E, additional, Ratner, E, additional, Silasi, D-A, additional, Azodi, M, additional, Schwartz, P E, additional, Rutherford, T J, additional, and Santin, A D, additional

Published
2014
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12. Mammaglobin B (SCGB2A1) is a novel tumour antigen highly differentially expressed in all major histological types of ovarian cancer: implications for ovarian cancer immunotherapy

Author

Bellone, S, primary, Tassi, R, additional, Betti, M, additional, English, D, additional, Cocco, E, additional, Gasparrini, S, additional, Bortolomai, I, additional, Black, J D, additional, Todeschini, P, additional, Romani, C, additional, Ravaggi, A, additional, Bignotti, E, additional, Bandiera, E, additional, Zanotti, L, additional, Pecorelli, S, additional, Ardighieri, L, additional, Falchetti, M, additional, Donzelli, C, additional, Siegel, E R, additional, Azodi, M, additional, Silasi, D-A, additional, Ratner, E, additional, Schwartz, P E, additional, Rutherford, T J, additional, and Santin, A D, additional

Published
2013
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13. Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy

Author

Bellone, S, primary, Roque, D, additional, Cocco, E, additional, Gasparrini, S, additional, Bortolomai, I, additional, Buza, N, additional, Abu-Khalaf, M, additional, Silasi, D-A, additional, Ratner, E, additional, Azodi, M, additional, Schwartz, P E, additional, Rutherford, T J, additional, Pecorelli, S, additional, and Santin, A D, additional

Published
2012
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15. Her2/neu extracellular domain shedding in uterine serous carcinoma: implications for immunotherapy with trastuzumab

Author

Todeschini, P, primary, Cocco, E, additional, Bellone, S, additional, Varughese, J, additional, Lin, K, additional, Carrara, L, additional, Guzzo, F, additional, Buza, N, additional, Hui, P, additional, Silasi, D-A, additional, Ratner, E, additional, Azodi, M, additional, Schwartz, P E, additional, Rutherford, T J, additional, Pecorelli, S, additional, and Santin, A D, additional

Published
2011
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17. hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma

Author

Cocco, E, primary, Hu, Z, additional, Richter, C E, additional, Bellone, S, additional, Casagrande, F, additional, Bellone, M, additional, Todeschini, P, additional, Krikun, G, additional, Silasi, D-A, additional, Azodi, M, additional, Schwartz, P E, additional, Rutherford, T J, additional, Buza, N, additional, Pecorelli, S, additional, Lockwood, C J, additional, and Santin, A D, additional

Published
2010
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18. In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma

Author

El-Sahwi, K, primary, Bellone, S, additional, Cocco, E, additional, Cargnelutti, M, additional, Casagrande, F, additional, Bellone, M, additional, Abu-Khalaf, M, additional, Buza, N, additional, Tavassoli, F A, additional, Hui, P, additional, Silasi, D-A, additional, Azodi, M, additional, Schwartz, P E, additional, Rutherford, T J, additional, Pecorelli, S, additional, and Santin, A D, additional

Published
2009
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19. Serum amyloid A (SAA): a novel biomarker for uterine serous papillary cancer

Author

Cocco, E, primary, Bellone, S, additional, El-Sahwi, K, additional, Cargnelutti, M, additional, Casagrande, F, additional, Buza, N, additional, Tavassoli, F A, additional, Siegel, E R, additional, Visintin, I, additional, Ratner, E, additional, Silasi, D-A, additional, Azodi, M, additional, Schwartz, P E, additional, Rutherford, T J, additional, Pecorelli, S, additional, and Santin, A D, additional

Published
2009
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20. Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia

Author

Zoledziewska, M, primary, Costa, G, additional, Pitzalis, M, additional, Cocco, E, additional, Melis, C, additional, Moi, L, additional, Zavattari, P, additional, Murru, R, additional, Lampis, R, additional, Morelli, L, additional, Poddie, F, additional, Frongia, P, additional, Pusceddu, P, additional, Bajorek, M, additional, Marras, A, additional, Satta, A M, additional, Chessa, A, additional, Pugliatti, M, additional, Sotgiu, S, additional, Whalen, M B, additional, Rosati, G, additional, Cucca, F, additional, and Marrosu, M G, additional

Published
2008
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27. Age at onset in multiple sclerosis

Author

Ligouri, M., primary, Pugliatti, M., additional, Giuliani, F., additional, Robertis, F. De, additional, Zimatore, G.B., additional, Livrea, P., additional, Trojano, M., additional, Cocco, E., additional, and Marrosu, M.G., additional

Published
2000
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28. Listening to the neurological teams for multiple sclerosis: the SMART project

Author

M. Rezzonico, Rocco Totaro, S. Bucello, Cinzia Cordioli, Alessandra Lugaresi, Alvino Bisecco, Martina Petruzzo, Paola Cavalla, Luisa Pastò, Eleonora Cocco, Giovanna Borriello, Roberta Fantozzi, S. Marangoni, M. Di Giuseppe, Edoardo Sessa, F. Caleri, Maria Liguori, W. Neri, M. G. Marini, L. Locatelli, G. L. Mancardi, C. Tortorella, K. Plewnia, S. Romano, P. Perini, Lucia Moiola, Francesco Patti, E. Mutta, Paola Chesi, Paola Valentino, A. Repice, Franco Granella, L. Alivernini, Marco Rovaris, M. Gattuso, Chesi P., Marini M.G., Mancardi G.L., Patti F., Alivernini L., Bisecco A., Borriello G., Bucello S., Caleri F., Cavalla P., Cocco E., Cordioli C., Di Giuseppe M., Fantozzi R., Gattuso M., Granella F., Liguori M., Locatelli L., Lugaresi A., Marangoni S., Moiola L., Mutta E., Neri W., Pasto L., Perini P., Petruzzo M., Plewnia K., Repice A.M., Rezzonico M., Romano S., Rovaris M., Sessa E., Tortorella C., Totaro R., Valentino P., Chesi, P., Marini, M. G., Mancardi, G. L., Patti, F., Alivernini, L., Bisecco, A., Borriello, G., Bucello, S., Caleri, F., Cavalla, P., Cocco, E., Cordioli, C., Di Giuseppe, M., Fantozzi, R., Gattuso, M., Granella, F., Liguori, M., Locatelli, L., Lugaresi, A., Marangoni, S., Moiola, L., Mutta, E., Neri, W., Pasto, L., Perini, P., Petruzzo, M., Plewnia, K., Repice, A. M., Rezzonico, M., Romano, S., Rovaris, M., Sessa, E., Tortorella, C., Totaro, R., and Valentino, P.

Subjects
Male, medicine.medical_specialty, Multiple Sclerosis, Neurology, Dermatology, Burnout, Job Satisfaction, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Surveys and Questionnaires, Health care, medicine, Humans, Active listening, 030212 general & internal medicine, Compassion fatigue, Descriptive statistics, business.industry, General Medicine, Middle Aged, Narrative medicine, burnout, compassion fatigue, narrative medicine, Psychiatry and Mental health, Cross-Sectional Studies, Italy, Family medicine, Quality of Life, Anxiety, Original Article, Female, Neurology (clinical), Empathy, medicine.symptom, Psychology, business, 030217 neurology & neurosurgery
Abstract

Objective Aim of the research was to define the quality of life of Italian neurologists and nurses’ professional caring for multiple sclerosis, to understand their living the clinical practice and identify possible signals of compassion fatigue. Material and methods One hundred five neurologists and nurses from 30 Italian multiple sclerosis centres were involved in an online quali-quantitative survey on the organization of care, combined with the Satisfaction and Compassion Fatigue Test and a collection of narratives. Descriptive statistics of the quantitative data were integrated with the results obtained by the narrative medicine methods of analysis. Results Most of the practitioners were neurologists, 46 average years old, 69% women, 43% part time dedicated to multiple sclerosis. An increased number of patients in the last 3 years were referred in 29 centres. Differences were found between neurologists and nurses. Physicians showed higher risks of burnout, reporting intensive working paces, lack of medical personnel, and anxiety caused by the precarious employment conditions. Nurses appeared more satisfied, although the reference to the lack of spaces, and the cross professional roles risk of compassion fatigue. Both positive and negative relationships of care were depicted as influencing the professional quality of life. Conclusion The interviewed neurological teams need to limit the risk of compassion fatigue, which appeared from the first years of the career. The prevalence of the risk among neurologists suggests more awareness among scientific societies and health care managers on the risk for this category, as first step to prevent it. Electronic supplementary material The online version of this article (10.1007/s10072-020-04301-z) contains supplementary material, which is available to authorized users.

Published
2020

29. Cerebrospinal fluid analysis and the determination of oligoclonal bands

Author

Eleonora Cocco, Giovanna De Luca, Elisabetta Zardini, Davide Giavarina, Debora Giunti, Maurizio Leone, Gaetano Desina, Gaetano Bernardi, Emilio Ciusani, Rinaldo Brivio, Sara Mariotto, Maddalena Ruggieri, Diego Franciotta, Enrico Fainardi, Mauro Zaffaroni, Elena Bazzigaluppi, Ivana Cataldo, Arianna Sala, Antonio Bertolotto, Francesco Lolli, Elisabetta Capello, Tiziana Biagioli, Gianna Costa, Andreina Paternoster, Eduardo Nobile-Orazio, Gabriella Passerini, Clara Ballerini, Claudia Giannotta, R. Leante, Guido Cavaletti, Massimiliano Castellazzi, Patrizia Sola, Roberta Bedin, Matteo Gastaldi, Paola Pettini, Sergio Ferrari, Gastaldi, M, Zardini, E, Leante, R, Ruggieri, M, Costa, G, Cocco, E, De Luca, G, Cataldo, I, Biagioli, T, Ballerini, C, Castellazzi, M, Fainardi, E, Pettini, P, Zaffaroni, M, Giunti, D, Capello, E, Bernardi, G, Ciusani, E, Giannotta, C, Nobile-Orazio, E, Bazzigaluppi, E, Passerini, G, Bedin, R, Sola, P, Brivio, R, Cavaletti, G, Sala, A, Bertolotto, A, Desina, G, Leone, M, Mariotto, S, Ferrari, S, Paternoster, A, Giavarina, D, Lolli, F, and Franciotta, D

Subjects
0301 basic medicine, Pathology, medicine.medical_specialty, Neurology, Neuroimmunology, Demyelinating Autoimmune Diseases, CNS, Dermatology, Intrathecal, NO, Laboratory diagnostics, Multiple sclerosis, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Internal medicine, Clinical information, Humans, Medicine, Intrathecal IgG synthesis, Isoelectric focusing, Laboratory diagnostics, Multiple sclerosis, Neuroimmunology, Intrathecal IgG synthesis, business.industry, Oligoclonal Bands, General Medicine, medicine.disease, Psychiatry and Mental health, 030104 developmental biology, Isoelectric focusing, Csf analysis, Neurology (clinical), business, 030217 neurology & neurosurgery
Abstract

This document presents the guidelines for the cerebrospinal fluid (CSF) analysis and the determination of oligoclonal bands (OCBs) as pivotal tests in neuroin flammatory pathologies of the central nervous system. The guidelines have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on the pathologies in which the CSF analysis is indicated, and, particularly, on those characterized by the presence of OCBs in the intrathecal compartment, indications and limits of CSF analysis and OCB determination, instructions for result interpretation, and agreed laboratory protocols (Appendix) are reported for the communicative community of neurologists and clinical pathologists.

Published
2017

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