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Your search keyword '"Di Cintio, A"' showing total 18 results
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18 results on '"Di Cintio, A"'

1. Antimicrobial efficacy of direct air gas soft jet plasma for the in vitro reduction of oral bacterial biofilms

Author

Puca, Valentina, primary, Marinacci, Beatrice, additional, Pinti, Morena, additional, Di Cintio, Federica, additional, Sinjari, Bruna, additional, Di Marcantonio, Maria Carmela, additional, Mincione, Gabriella, additional, Acharya, Tirtha Raj, additional, Kaushik, Nagendra Kumar, additional, Choi, Eun Ha, additional, Sallese, Michele, additional, Guarnieri, Simone, additional, Grande, Rossella, additional, and Perrotti, Vittoria, additional

Published
2024
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4. Machine learning to improve interpretability of clinical, radiological and panel-based genomic data of glioma grade 4 patients undergoing surgical resection

Author

Dal Bo, Michele, primary, Polano, Maurizio, additional, Ius, Tamara, additional, Di Cintio, Federica, additional, Mondello, Alessia, additional, Manini, Ivana, additional, Pegolo, Enrico, additional, Cesselli, Daniela, additional, Di Loreto, Carla, additional, Skrap, Miran, additional, and Toffoli, Giuseppe, additional

Published
2023
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5. Is it possible to predict the severity of acute appendicitis? Reliability of predictive models based on easily available blood variables

Author

Afzal, Barza, primary, Cirocchi, Roberto, additional, Dawani, Aruna, additional, Desiderio, Jacopo, additional, Di Cintio, Antonio, additional, Di Nardo, Domenico, additional, Farinacci, Federico, additional, Fung, James, additional, Gemini, Alessandro, additional, Guerci, Lorenzo, additional, Kam, Sen Yin Melina, additional, Lakunina, Svetlana, additional, Madi, Lee, additional, Mazzetti, Stefano, additional, Nadyrshine, Bakhtiar, additional, Shams, Ola, additional, Ranucci, Maria Chiara, additional, Ricci, Francesco, additional, Sharmin, Afroza, additional, Trastulli, Stefano, additional, Yasin, Tanzela, additional, Bond-Smith, Giles, additional, and Tebala, Giovanni D., additional

Published
2023
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6. Parathyroid hormone-related peptide and parathyroid hormone-related peptide receptor type 1 in locally advanced laryngeal cancer as prognostic indicators of relapse and survival

Author

Giovanni Almadori, Antonella Coli, Eugenio De Corso, Dario Antonio Mele, Stefano Settimi, Giovanni Di Cintio, Francesca Brigato, Domenico Scannone, Libero Lauriola, and Franco Oreste Ranelletti

Subjects
Cancer Research, Parathyroid Hormone-Related Protein, Cetuximab, Prognosis, Bio-radiotherapy with cetuximab, Oncology, Laryngeal cancer, HER1, Genetics, Humans, Prognostic and predictive role, Settore MED/31 - OTORINOLARINGOIATRIA, Neoplasm Recurrence, Local, Laryngeal Neoplasms, PTHrP and PTH1R, Receptor, Parathyroid Hormone, Type 1, Retrospective Studies
Abstract

Background Parathyroid hormone-related peptide (PTHrP) overexpression and poor patient outcome have been reported for many human tumors, but no studies are available in laryngeal cancer. Therefore, we studied the expression of PTHrP and its receptor, parathyroid hormone-related peptide receptor type 1 (PTH1R), in primary locally advanced laryngeal squamous cell carcinomas (LALSCC) also in relation to the clinical outcome of patients. Methods We conducted a retrospective exploratory study, using immunohistochemistry, on PTHrP, PTH1R and HER1 expressions in LALSCC of 66 patients treated with bio-radiotherapy with cetuximab. Results The expressions of PTHrP and PTH1R in LALSCC were associated with the degree of tumor differentiation (p = 0.01 and 0.04, respectively). Poorly differentiated tumors, with worse prognosis, expressed PTHrP at nuclear level and were PTH1R negative. PTHrP and PTH1R were expressed at cytoplasmic level in normal larynx epithelium and more differentiated laryngeal cancer cells, suggesting an autocrine/paracrine role of PTHrP in squamous cell differentiation of well differentiated tumors with good prognosis. Eighty-one percent HER1 positive tumors expressed PTHrP (p PTHrP gene by HER1 signaling. In multivariable analyses, patients with PTHrP positive tumors had a higher relative risk of relapse (HR = 5.49; CI 95% = 1.62–22.24; p = 0.006) and survival (HR = 8.21; CI 95% = 1.19–105.00; p = 0.031) while those with PTH1R positive tumors showed a lower relative risk of relapse (HR = 0.18; CI 95% = 0.04–0.62; p = 0.002) and survival (HR = 0.18; CI 95% = 0.04–0.91; p = 0.029). Conclusions In LALSCC nuclear PTHrP and absence of PTH1R expressions could be useful in predicting response and/or resistance to cetuximab in combined therapies, contributing to an aggressive behavior of tumor cells downstream to HER1.

Published
2022
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7. Parathyroid hormone-related peptide and parathyroid hormone-related peptide receptor type 1 in locally advanced laryngeal cancer as prognostic indicators of relapse and survival

Author

Almadori, Giovanni, primary, Coli, Antonella, additional, De Corso, Eugenio, additional, Mele, Dario Antonio, additional, Settimi, Stefano, additional, Di Cintio, Giovanni, additional, Brigato, Francesca, additional, Scannone, Domenico, additional, Lauriola, Libero, additional, and Ranelletti, Franco Oreste, additional

Published
2022
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8. Nuclear HER3 expression improves the prognostic stratification of patients with HER1 positive advanced laryngeal squamous cell carcinoma

Author

Almadori, Giovanni, primary, Coli, Antonella, additional, De Corso, Eugenio, additional, Mele, Dario Antonio, additional, Settimi, Stefano, additional, Di Cintio, Giovanni, additional, Brigato, Francesca, additional, Scannone, Domenico, additional, Carey, Thomas E., additional, Paludetti, Gaetano, additional, Lauriola, Libero, additional, and Ranelletti, Franco Oreste, additional

Published
2021
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9. Seascape connectivity of European anchovy in the Central Mediterranean Sea revealed by weighted Lagrangian backtracking and bio-energetic modelling

Author

Falcini, Federico, primary, Corrado, Raffaele, additional, Torri, Marco, additional, Mangano, Maria Cristina, additional, Zarrad, Rafik, additional, Di Cintio, Antonio, additional, Palatella, Luigi, additional, Jarboui, Othman, additional, Missaoui, Hechmi, additional, Cuttitta, Angela, additional, Patti, Bernardo, additional, Santoleri, Rosalia, additional, Sarà, Gianluca, additional, and Lacorata, Guglielmo, additional

Published
2020
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10. The usefulness of the IMAP propeller flap for trachea and tracheostome reconstruction after resection of parastomal recurrence of squamous cell carcinoma following salvage total laryngectomy

Author

Almadori, Giovanni, primary, Di Cintio, Giovanni, additional, De Corso, Eugenio, additional, Mele, Dario Antonio, additional, Settimi, Stefano, additional, Almadori, Aurora, additional, Cina, Alessandro, additional, Visconti, Giuseppe, additional, Paludetti, Gaetano, additional, and Salgarello, Marzia, additional

Published
2020
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12. Lymph node retrieval and examination during the implementation of extended lymph node dissection for gastric cancer in a non-specialized western institution

Author

Giovanni Battista Grassi, Marco Catarci, Leonardo Antonio Montemurro, Augusto Belardi, Luigi Coppola, Antonio Di Cintio, Maurizio Koch, Sabrina Ghinassi, and Luigi Pinnarelli

Subjects
medicine.medical_specialty, Prognostic factor, Pathology, Nodal staging, Stomach Neoplasms, medicine, Humans, Prospective Studies, Stage (cooking), Gastric resection, Lymph node, Neoplasm Staging, Retrospective Studies, business.industry, Reproducibility of Results, Cancer, medicine.disease, Surgery, Dissection, medicine.anatomical_structure, Lymphatic Metastasis, Lymph Node Excision, Lymph Nodes, Lymph, business
Abstract

The optimal degree of lymph node dissection for gastric cancer is still matter of debate. Particularly, there are serious doubts about the reproducibility of extended lymph node dissection in western surgical units, and no studies to date have investigated factors influencing lymph node retrieval and examination during the learning curve. Univariate and multivariate retrospective analysis of 21 variables were carried out on a prospective series of 313 consecutive resections for gastric cancer performed by ten different surgeons, with lymph node retrieval and analysis performed by ten different pathologists. Endpoints were number of examined lymph nodes per patient, number of cases with inadequate nodal staging (

Published
2010
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14. [Untitled]

Author

Maurizio Marchini, R. Mezzopane, Fabio Parazzini, E. Di Cintio, Luca Tozzi, L. Luchini, and Luigi Fedele

Subjects
Gynecology, medicine.medical_specialty, Pregnancy, Epidemiology, Obstetrics, business.industry, media_common.quotation_subject, medicine.disease, Confidence interval, Menstruation, Relative risk, medicine, Menarche, Risk factor, business, Menstrual cycle, media_common
Abstract

In order to analyze risk factors for dysmenorrhoea, we conducted a case-control study. Cases were 106 women (median age 27 years) with moderate or severe dysmenorrhoea lasting 12 months or more. Controls were 145 women (median age 26 years) without dysmenorrhoea, admitted for routine gynecological examination at the outpatient gynecological services of the same clinic where cases had been identified. In comparison with women reporting short menstrual cycles (every 25 days or less) the relative risk (RR) of dysmenorrhoea was 2.0 and 2.6, respectively, in those reporting their menstrual cycles of 26-30 days and of 31 days or more, and the RR was 3.6 (95% confidence interval (CI): 1.0-13.4) for women reporting totally irregular menstrual cycles. The estimated RRs were, in comparison with women reporting menstrual flows lasting 4 days or less, respectively 2.2 and 1.9 in those reporting menstrual flows lasting 5 and 6 days or more. Fourty-four (58%) cases but only seven (5%) controls reported heavy menstrual flows (RR in comparison with women reporting slight or normal menstrual flow 12.6, 95% CI: 5.0-32.1). As regards dietary factors, no associations emerged between the various food items, with the exception of cheese and eggs, which tended to be more frequently consumed by cases than controls. The results of this study suggest that the risk of dysmenorrhoea is higher in women with irregular, long and heavy menstrual flows. No association emerged between reproductive history and dysmenorrhoea. Likewise, no clear relationship emerged between intake of several dietary factors and risk dysmenorrhoea.

Published
1997
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17. Lymph node retrieval and examination during the implementation of extended lymph node dissection for gastric cancer in a non-specialized western institution

Author

Catarci, Marco, primary, Montemurro, Leonardo Antonio, additional, Di Cintio, Antonio, additional, Ghinassi, Sabrina, additional, Coppola, Luigi, additional, Pinnarelli, Luigi, additional, Belardi, Augusto, additional, Koch, Maurizio, additional, and Grassi, Giovanni Battista, additional

Published
2010
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