1. Phylogenetic characterization of Setaria equina and its association with other filarids
- Author
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Anjali Devi, Daya Shanker, and Vikrant Sudan
- Subjects
musculoskeletal diseases ,Setaria ,Sequence analysis ,Setaria Nematode ,Zoology ,Biology ,Homology (biology) ,Electron Transport Complex IV ,Monophyly ,parasitic diseases ,Animals ,Humans ,Clade ,Filarioidea ,Phylogeny ,General Veterinary ,Phylogenetic tree ,Genetic Variation ,Helminth Proteins ,General Medicine ,Dipetalonema ,biology.organism_classification ,Filariasis ,Infectious Diseases ,Sister group ,Insect Science ,Parasitology - Abstract
Molecular characterization studies on Setaria equina are limited. The present study aimed to characterize S. equina at the cytochrome c oxidase gene and to examine its phylogenetic relationships with other filarid species. Sequence analysis showed 100% nucleotide homology with an S. equina sequence from Italy (AJ544873). However, both sequences exhibited 7 nucleotide substitutions from a S. equina donkey isolate from Egypt (MK541847). Overall, S. equina formed a monophyletic sister group to Setaria tundra. All Setaria spp. examined formed a separate group on the phylogenetic tree that was related to corresponding Onchocerca spp. and Dirofilaria spp. clades. Human filarid worms-Brugia spp. and Wuchereria spp. grouped in a separate clade alongside Theilezia spp. Dipetalonema spp.-formed a separate group at the top of the tree.
- Published
- 2020