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To review the current literature regarding sexual dysfunction and interstitial cystitis/bladder pain syndrome (IC/BPS). Our goal was to review the epidemiology and overlap of these two conditions as well discuss the success of various IC/BPS treatment modalities with improving sexual function. Women with IC/BPS have a much higher incidence of sexual dysfunction as compared to controls, and this is often a significant predictor of poor quality of life. IC/BPS is thought to have various phenotypes and is associated with a number of overlapping chronic conditions which may contribute to sexual dysfunction thus making an accurate diagnosis imperative. Various treatments for IC/BPS may improve certain domains of sexual function. It is not surprising that IC/BPS, a chronic pelvic pain condition, negatively affects sexual function. More research is needed not just on the prevalence of sexual dysfunction in this patient population, but specifically on treatment options and ways to improve sexual function in these distressed patients.