1. Syndrome-related outcomes following posterior vault distraction osteogenesis
- Author
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Cesar Augusto Raposo-Amaral, Yuri Moresco Oliveira, Rafael Denadai, Enrico Ghizoni, and Cassio Eduardo Raposo-Amaral
- Subjects
musculoskeletal diseases ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Blood transfusion ,medicine.medical_treatment ,Osteogenesis, Distraction ,Apert syndrome ,030230 surgery ,Craniosynostoses ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Child ,Retrospective Studies ,Intracranial pressure ,business.industry ,Craniofacial Dysostosis ,Crouzon syndrome ,Retrospective cohort study ,General Medicine ,Perioperative ,Acrocephalosyndactylia ,medicine.disease ,Surgery ,030220 oncology & carcinogenesis ,Pediatrics, Perinatology and Child Health ,Pfeiffer syndrome ,Distraction osteogenesis ,Neurology (clinical) ,business - Abstract
The most commonly occurring syndromic craniosynostoses are Apert syndrome, Crouzon syndrome, Pfeiffer syndrome, and Saethre-Chotzen syndrome. There is insufficient data regarding postoperative syndrome–related outcomes following the posterior vault distraction osteogenesis (PVDO) procedure, as well as data addressing whether or not additional procedures will be subsequently necessary to comprehensively treat children who undergo PVDO. Thus, the objective of this study is to describe and compare syndrome-related potential complications and outcomes associated with the PVDO procedure. An observational retrospective study was performed on consecutive patients (n=24) with Apert syndrome, Crouzon syndrome, Pfeiffer syndrome, or Saethre-Chotzen syndrome, respectively, who underwent PVDO between 2012 and 2019. Demographic data (patient gender and age when the PVDO procedure was performed), diagnosis, surgery-related data, and outcome data (perioperative and midterm complications and need for additional surgery) were verified. Total relative blood transfusion volumes per kilogram for the patients were as follows: 22.75 ± 9.30 ml for Apert syndrome, 10.73 ± 2.28 ml for Crouzon syndrome (Apert versus Crouzon, p
- Published
- 2021