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43 results on '"Ferreira, Joaquim J."'

3. Atrial fibrillation risk on Parkinson’s disease – a systematic review and meta-analysis

Author

Cereja, Fátima, Alves, Mariana, Ferreira, Joaquim J, Caldeira, Daniel, and Repositório da Universidade de Lisboa

Subjects
Stroke, Meta-analysis, Parkinson’s disease, Atrial flutter, Hematology, Cardiology and Cardiovascular Medicine, Atrial fibrillation, Observational, Arrhythmia
Abstract

© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023, The association of Parkinson's Disease (PD) with atrial fibrillation (AF) is not well established and previous studies' results were heterogeneous. This review aimed to evaluate if patients with PD are at increased risk of having AF. MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science, were searched from inception May 2021. Two reviewers independently selected observational studies with data allowing to estimate the risk of atrial fibrillation in PD patients compared with no-PD controls. Pooled estimates Odds Ratio (OR) and 95% confidence intervals (CIs) were derived through meta-analysis. Heterogeneity was assessed using I2 test. The risk of bias of individual studies was evaluated using the ROBINS-I tool. The study protocol was registered at PROSPERO: CRD42020216572. Seven studies were included: five case-control studies and two cohort studies. Three of the studies included were a population-based study. No significant difference was detected between PD and controls regarding atrial fibrillation (OR 1.10, 95% CI 0.81 to 1.49). Early PD present a significant higher risk of AF (OR 1.55, 95% CI 1.00 to 2.40, I2 98%). The overall risk of bias was serious, with only two studies being considered as having moderate risk. The best evidence available do not support that there is an increased risk of AF in PD patients. Further studies are needed to better conclude if there is a relation between AF and PD.

Published
2023

6. Opicapone as an Add-on to Levodopa in Patients with Parkinson’s Disease Without Motor Fluctuations: Rationale and Design of the Phase III, Double-Blind, Randomised, Placebo-Controlled EPSILON Trial

Author

Ferreira, Joaquim J., primary, Poewe, Werner, additional, Rascol, Olivier, additional, Stocchi, Fabrizio, additional, Antonini, Angelo, additional, Moreira, Joana, additional, Pereira, Ana, additional, Rocha, José-Francisco, additional, and Soares-da-Silva, Patrício, additional

Published
2022
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7. The sham effect of invasive interventions in chronic coronary syndromes: a systematic review and meta-analysis

Author

Palma, Catarina, David, Cláudio, Fernandes, Ricardo M., Pinto, Fausto J., Costa, João, Ferreira, Joaquim J, Caldeira, Daniel, and Repositório da Universidade de Lisboa

Subjects
Placebos, Canada, Invasive treatment, Sham procedure, Quality of Life, Humans, Chronic coronary syndromes, Sham effect, Coronary Artery Disease, Syndrome, Cardiology and Cardiovascular Medicine, Angina Pectoris, Randomized Controlled Trials as Topic
Abstract

© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data., Background: Some patients with chronic coronary syndromes undergo invasive procedures but the efficacy of such interventions remains to be robustly established by randomised sham-controlled trials (RCTs). Purpose: To determine the sham effect in patients with chronic coronary syndromes enrolled in RCTs by performing a systematic review and meta-analysis. Methods: In April 2022, we performed a literature search for published patient-blind RCTs (CENTRAL, MEDLINE®, PsycINFO, and reference lists) with sham procedures, reporting the pre-post effects in the invasive sham arm among patients with Canadian cardiovascular society (CCS) angina or angina equivalents. Results: 16 RCTs were included with 546 patients in the sham arm. Pooled results showed that sham interventions were associated with: improvement of 7% (95% CI 2-11%; I2 = 0%) in exercise time; decrease of 0.78 (95% CI - 1.10 to - 0.47; I2 = 75%) in CCS angina class; decrease of 53% (95% CI 24-71%; I2 = 96%) and 25% (95% CI 20-29%; I2 = 0%) in anginal episodes and nitroglycerine (NTG) use, respectively. Pooled results also showed an improvement in the physical functioning, angina frequency, treatment satisfaction, and disease perception domains of the Seattle Angina Questionnaire (SAQ). Conclusion: Sham interventions in patients with chronic coronary syndromes were associated with a significant decrease in anginal episodes, NTG use, and CCS angina class and increased SAQ quality of life and exercise time. These results highlight the need for previous non sham-controlled trials to be interpreted with caution, and the importance of new invasive interventions to be evaluated versus a sham procedure.

Published
2022

9. Opicapone versus placebo in the treatment of Parkinson’s disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial

Author

Chaudhuri, K. Ray, primary, Odin, Per, additional, Ferreira, Joaquim J., additional, Antonini, Angelo, additional, Rascol, Olivier, additional, Kurtis, Mónica M., additional, Storch, Alexander, additional, Bannister, Kirsty, additional, Soares-da-Silva, Patrício, additional, Costa, Raquel, additional, Magalhães, Diogo, additional, and Rocha, José Francisco, additional

Published
2022
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10. Low risk of haematomas with intramuscular vaccines in anticoagulated patients: a systematic review with meta-analysis

Author

Caldeira, Daniel, Rodrigues, Bárbara Sucena, Alves, Mariana, Pinto, Fausto J., Ferreira, Joaquim J, and Repositório da Universidade de Lisboa

Subjects
Haemorrhage, Flu, anticoagulation, Bleeding, Hematology, Vaccine
Abstract

© The Author(s). 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data., Introduction: The summary of product characteristics of vaccines administered intramuscularly, including the vaccine for coronavirus SARS-CoV-2 (COVID-19) and Influenza, warned for risks of bleeding in patients treated with oral anticoagulants. We aimed to estimate the incidence of major bleeding events in this setting and to compare these risks against other vaccination routes. Methods: This systematic review included all prospective and retrospective studies enrolling anticoagulated patients that received intramuscular vaccination, published until December 2020 in CENTRAL, MEDLINE and EMBASE. The outcomes of interest were major bleeding and haematoma related with vaccination. The incidence of the outcomes was estimated through a random-effects meta-analysis using the Freeman-Turkey transformation. The results are expressed in percentages, with 95%-confidence intervals (95%CI), limited between 0 and 100%. When studies compared intramuscular vaccination vs. other route, the data were compared and pooled using random-effects meta-analysis. Risk ratios (RR) with 95%CI were reported. Results: Overall 16 studies with 642 patients were included. No major bleeding event was reported. The pooled incidence of haematomas following vaccination (mostly against Influenza) in patients treated with oral anticoagulants (mostly warfarin; no data with DOACs / NOACs) was 0.46% (95%CI 0-1.53%). Three studies evaluated the intramuscular vs. subcutaneous route of vaccination. Intramuscular vaccines did not increase the risk of haematoma (RR 0.53, 95%CI 0.10-2.82) compared with subcutaneous route. Conclusions: Intramuscular vaccination in anticoagulated patients is safe with very low incidence of haematomas and the best available evidence suggests that using the intramuscular route does not increase the risk of haematomas compared with the subcutaneous route.

Published
2022

12. Validation of quantitative gait analysis systems for Parkinson’s disease for use in supervised and unsupervised environments

Author

Alberto, Sara, primary, Cabral, Sílvia, additional, Proença, João, additional, Pona-Ferreira, Filipa, additional, Leitão, Mariana, additional, Bouça-Machado, Raquel, additional, Kauppila, Linda Azevedo, additional, Veloso, António P., additional, Costa, Rui M., additional, Ferreira, Joaquim J., additional, and Matias, Ricardo, additional

Published
2021
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15. A distinct neuromelanin magnetic resonance imaging pattern in parkinsonian multiple system atrophy

Author

Simões, Rita Moiron, primary, Castro Caldas, Ana, additional, Grilo, Joana, additional, Correia, Daisy, additional, Guerreiro, Carla, additional, Pita Lobo, Patrícia, additional, Valadas, Anabela, additional, Fabbri, Marguerita, additional, Correia Guedes, Leonor, additional, Coelho, Miguel, additional, Rosa, Mario Miguel, additional, Ferreira, Joaquim J., additional, and Reimão, Sofia, additional

Published
2020
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21. Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment – the ComOn-study

Author

Geritz, Johanna, primary, Maetzold, Sara, additional, Steffen, Maren, additional, Pilotto, Andrea, additional, Corrà, Marta F., additional, Moscovich, Mariana, additional, Rizzetti, Maria C., additional, Borroni, Barbara, additional, Padovani, Alessandro, additional, Alpes, Annekathrin, additional, Bang, Corinna, additional, Barcellos, Igor, additional, Baron, Ralf, additional, Bartsch, Thorsten, additional, Becktepe, Jos S., additional, Berg, Daniela, additional, Bergeest, Lu M., additional, Bergmann, Philipp, additional, Bouça-Machado, Raquel, additional, Drey, Michael, additional, Elshehabi, Morad, additional, Farahmandi, Susan, additional, Ferreira, Joaquim J., additional, Franke, Andre, additional, Friederich, Anja, additional, Geisler, Corinna, additional, Hüllemann, Philipp, additional, Gierthmühlen, Janne, additional, Granert, Oliver, additional, Heinzel, Sebastian, additional, Heller, Maren K., additional, Hobert, Markus A., additional, Hofmann, Marc, additional, Jemlich, Björn, additional, Kerkmann, Laura, additional, Knüpfer, Stephanie, additional, Krause, Katharina, additional, Kress, Maximilian, additional, Krupp, Sonja, additional, Kudelka, Jennifer, additional, Kuhlenbäumer, Gregor, additional, Kurth, Roland, additional, Leypoldt, Frank, additional, Maetzler, Corina, additional, Maia, Luis F., additional, Moewius, Andreas, additional, Neumann, Patricia, additional, Niemann, Katharina, additional, Ortlieb, Christian T., additional, Paschen, Steffen, additional, Pham, Minh H., additional, Puehler, Thomas, additional, Radloff, Franziska, additional, Riedel, Christian, additional, Rogalski, Marten, additional, Sablowsky, Simone, additional, Schanz, Elena M., additional, Schebesta, Linda, additional, Schicketmüller, Andreas, additional, Studt, Simone, additional, Thieves, Martina, additional, Tönges, Lars, additional, Ullrich, Sebastian, additional, Urban, Peter P., additional, Vila-Chã, Nuno, additional, Wiegard, Anna, additional, Warmerdam, Elke, additional, Warnecke, Tobias, additional, Weiss, Michael, additional, Welzel, Julius, additional, Hansen, Clint, additional, and Maetzler, Walter, additional

Published
2020
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24. Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson’s disease

Author

Vicente Miranda, Hugo, primary, Cássio, Rafaela, additional, Correia-Guedes, Leonor, additional, Gomes, Marcos António, additional, Chegão, Ana, additional, Miranda, Elisa, additional, Soares, Tiago, additional, Coelho, Miguel, additional, Rosa, Mário Miguel, additional, Ferreira, Joaquim J., additional, and Outeiro, Tiago Fleming, additional

Published
2017
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27. Erratum to: A systematic review of the characteristics and validity of monitoring technologies to assess Parkinson’s disease

Author

Godinho, Catarina, primary, Domingos, Josefa, additional, Cunha, Guilherme, additional, Santos, Ana T., additional, Fernandes, Ricardo M., additional, Abreu, Daisy, additional, Gonçalves, Nilza, additional, Matthews, Helen, additional, Isaacs, Tom, additional, Duffen, Joy, additional, Al-Jawad, Ahmed, additional, Larsen, Frank, additional, Serrano, Artur, additional, Weber, Peter, additional, Thoms, Andrea, additional, Sollinger, Stefan, additional, Graessner, Holm, additional, Maetzler, Walter, additional, and Ferreira, Joaquim J., additional

Published
2016
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28. A systematic review of the characteristics and validity of monitoring technologies to assess Parkinson’s disease

Author

Godinho, Catarina, primary, Domingos, Josefa, additional, Cunha, Guilherme, additional, Santos, Ana T., additional, Fernandes, Ricardo M., additional, Abreu, Daisy, additional, Gonçalves, Nilza, additional, Matthews, Helen, additional, Isaacs, Tom, additional, Duffen, Joy, additional, Al-Jawad, Ahmed, additional, Larsen, Frank, additional, Serrano, Artur, additional, Weber, Peter, additional, Thoms, Andrea, additional, Sollinger, Stefan, additional, Graessner, Holm, additional, Maetzler, Walter, additional, and Ferreira, Joaquim J., additional

Published
2016
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31. Quantitative home-based assessment of Parkinson’s symptoms: The SENSE-PARK feasibility and usability study

Author

Ferreira, Joaquim J., primary, Godinho, Catarina, additional, Santos, Ana T., additional, Domingos, Josefa, additional, Abreu, Daisy, additional, Lobo, Raquel, additional, Gonçalves, Nilza, additional, Barra, Marcio, additional, Larsen, Frank, additional, Fagerbakke, Øyvind, additional, Akeren, Ingvild, additional, Wangen, Hilde, additional, Serrano, J. Artur, additional, Weber, Peter, additional, Thoms, Andrea, additional, Meckler, Stefan, additional, Sollinger, Stefan, additional, van Uem, Janet, additional, Hobert, Markus A., additional, Maier, Katrin S., additional, Matthew, Helen, additional, Isaacs, Tom, additional, Duffen, Joy, additional, Graessner, Holm, additional, and Maetzler, Walter, additional

Published
2015
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35. Time- and frequency-domain parameters of heart rate variability and sympathetic skin response in Parkinson’s disease

Author

Maetzler, Walter, primary, Karam, Marie, additional, Berger, Monika Fruhmann, additional, Heger, Tanja, additional, Maetzler, Corina, additional, Ruediger, Heinz, additional, Bronzova, Juliana, additional, Lobo, Patricia Pita, additional, Ferreira, Joaquim J., additional, Ziemssen, Tjalf, additional, and Berg, Daniela, additional

Published
2014
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