12 results on '"Florence E. Turrentine"'
Search Results
2. Specialty-Specific Readmission Risk Models Outperform General Models in Estimating Hepatopancreatobiliary Surgery Readmission Risk
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Florence E. Turrentine, Timothy L. McMurry, R. Scott Jones, Mark E. Smolkin, and Victor M. Zaydfudim
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medicine.medical_specialty ,Receiver operating characteristic ,business.industry ,medicine.medical_treatment ,Gastroenterology ,Specialty ,Nomogram ,Surgery ,Acs nsqip ,Pancreatectomy ,Medicine ,Derivation ,Hepatectomy ,business ,Readmission risk - Abstract
BACKGROUND Readmissions are costly and inconvenient for patients, and occur frequently in hepatopancreatobiliary (HPB) surgery practice. Readmission prediction tools exist, but most have not been designed or tested in the HPB patient population. METHODS Pancreatectomy and hepatectomy operation-specific readmission models defined as subspecialty readmission risk assessments (SRRA) were developed using clinically relevant data from merged 2014-15 ACS NSQIP Participant Use Data Files and Procedure Targeted datasets. The two derived procedure-specific models were tested along with 6 other readmission models in institutional validation cohorts in patients who had pancreatectomy or hepatectomy, respectively, between 2013 and 2017. Models were compared using area under the receiver operating characteristic curves (AUC). RESULTS A total of 16,884 patients (9169 pancreatectomy and 7715 hepatectomy) were included in the derivation models. A total of 665 patients (383 pancreatectomy and 282 hepatectomy) were included in the validation models. Specialty-specific readmission models outperformed general models. AUC characteristics of the derived pancreatectomy and hepatectomy SRRA (pancreatectomy AUC=0.66, hepatectomy AUC=0.74), modified Readmission After Pancreatectomy (AUC=0.76), and modified Readmission Risk Score for hepatectomy (AUC=0.78) outperformed general models for readmission risk: LOS/2 + ASA integer-based score (pancreatectomy AUC=0.58, hepatectomy AUC=0.66), LACE Index (pancreatectomy AUC=0.54, hepatectomy AUC=0.62), Unplanned Readmission Nomogram (pancreatectomy AUC=0.52, hepatectomy AUC=0.55), and institutional ARIA (pancreatectomy AUC=0.46, hepatectomy AUC=0.58). CONCLUSION HPB readmission risk models using 30-day subspecialty-specific data outperform general readmission risk tools. Hospitals and practices aiming to decrease readmissions in HPB surgery patient populations should use specialty-specific readmission reduction strategies.
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- 2021
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3. Preoperative opioid use is associated with increased risk of postoperative complications within a colorectal-enhanced recovery protocol
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Bethany M. Sarosiek, Elizabeth D. Krebs, Florence E. Turrentine, Sook C. Hoang, Robert H. Thiele, Traci L. Hedrick, Charles M. Friel, and Taryn E. Hassinger
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medicine.medical_specialty ,business.industry ,Opioid use ,Retrospective cohort study ,Hepatology ,Logistic regression ,Colorectal surgery ,03 medical and health sciences ,0302 clinical medicine ,Increased risk ,Enhanced recovery ,030220 oncology & carcinogenesis ,Internal medicine ,Medicine ,030211 gastroenterology & hepatology ,Surgery ,business ,Abdominal surgery - Abstract
As the opioid epidemic escalates, preoperative opioid use has become increasingly common. Recent studies associated preoperative opioid use with postoperative morbidity. However, limited study of its impact on patients within enhanced recovery protocols (ERP) exists. We assessed the impact of preoperative opioid use on postoperative complications among colorectal surgery patients within an ERP, hypothesizing that opioid-exposed patients would be at increased risk of complications. Elective colorectal cases from August 2013 to June 2017 were reviewed in a retrospective cohort study comparing preoperative opioid-exposed patients to opioid-naive patients. Postoperative complications were defined as a composite of complications captured by the American College of Surgeons National Surgical Quality Improvement Program. Logistic regression identified risk factors for postoperative complications. 707 patients were identified, including 232 (32.8%) opioid-exposed patients. Opioid-exposed patients were younger (57.9 vs 61.9 years; p
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- 2020
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4. Safety of Major Abdominal Operations in the Elderly: A Study of Geriatric-Specific Determinants of Health
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Victor M. Zaydfudim, R. Scott Jones, Florence E. Turrentine, Allison N. Martin, and Darian L Hoagland
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Male ,medicine.medical_specialty ,Original Scientific Report ,MEDLINE ,030230 surgery ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Residence Characteristics ,Risk Factors ,Abdomen ,medicine ,Humans ,Postoperative Period ,Social determinants of health ,Mobility Limitation ,Geriatric Assessment ,Third-Party Consent ,Digestive System Surgical Procedures ,Aged ,Retrospective Studies ,Aged, 80 and over ,business.industry ,Age Factors ,Perioperative ,Vascular surgery ,Patient Discharge ,Cardiac surgery ,Elective Surgical Procedures ,Cardiothoracic surgery ,030220 oncology & carcinogenesis ,Emergency medicine ,Accidental Falls ,Female ,Surgery ,Abdominal operations ,business ,Abdominal surgery - Abstract
Background Preoperative assessment of geriatric-specific determinants of health may enhance perioperative risk stratification among elderly patients. This study examines effects of geriatric-specific variables on postoperative outcomes in patients undergoing elective major abdominal operations. Methods Patients included in the ACS NSQIP pilot Geriatric Surgery Research File program who underwent elective pancreatic, liver, and colorectal operations between 2014 and 2016 were examined. Multivariable analyses were performed to evaluate associations between patient-specific geriatric variables and risk of death, morbidity, readmission, and discharge destination. Results A total of 4165 patients were included. Patients ≥85 years were more likely to die, experience postoperative morbidity, and be discharged to a facility (all p ≤ 0.039) than younger patients. Preoperatively, patients ≥85 years were more likely to use a mobility aid, have a prior fall, have consent signed by a surrogate, and to live alone at home prior to operation (all p 0.055). Patients 75–84 and ≥85 years were more likely to be discharged to facility (OR 2.33 and 4.75, respectively, both p
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- 2020
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5. Modifiable Factors to Prevent Prolonged Length of Stay after Sleeve Gastrectomy
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Hunter Mehaffey, Bruce D. Schirmer, Florence E. Turrentine, Peter D Adams, Peter T. Hallowell, and Max O. Meneveau
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Adult ,Male ,Sleeve gastrectomy ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,medicine.medical_treatment ,Logistic regression ,Body Mass Index ,chemistry.chemical_compound ,Primary outcome ,Gastrectomy ,Risk Factors ,Humans ,Medicine ,Early discharge ,Retrospective Studies ,Morning ,Creatinine ,Nutrition and Dietetics ,business.industry ,Length of Stay ,Middle Aged ,Patient Discharge ,Obesity, Morbid ,Surgery ,chemistry ,Female ,Laparoscopy ,business ,Body mass index ,American society of anesthesiologists - Abstract
Early discharge after laparoscopic sleeve gastrectomy (SG) is common and safe, but two-thirds of patients are still hospitalized longer than 1 day. The purpose of this study was to evaluate factors associated with early discharge at a single institution with intention to discharge on postoperative day 1. Retrospective review of preoperative, intraoperative, and postoperative factors was performed for all patients undergoing SG at an academic hospital between 2010 and 2016. The primary outcome measure was length of stay (LOS). Multivariate logistic regression was used to identify independent predictors of prolonged LOS. A total of 367 patients undergoing SG were included. Two hundred eighty-seven (78%) were women and 294 (80%) were Caucasian. Mean age was 45.5 years and mean body mass index (BMI) was 48.7 kg/m2. One hundred twenty-three patients (33.5%) had a LOS ≤ 1 day. Compared to patients staying ≥ 2 days, early discharge patients had significantly lower BMI, creatinine, and American Society of Anesthesiologists class, were more likely to be White, married, have private insurance, and were more likely to have a morning start and no postoperative upper gastrointestinal (UGI) swallow study. Regression analysis demonstrated several independent predictors of prolonged LOS including institutional experience (OR 0.5, p
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- 2019
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6. Clinical Factors and Postoperative Impact of Bile Leak After Liver Resection
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Florence E. Turrentine, George J. Stukenborg, Todd W. Bauer, Allison N. Martin, Victor M. Zaydfudim, Sowmya Narayanan, and Reid B. Adams
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Anastomotic Leak ,030230 surgery ,Gastroenterology ,Article ,Resection ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Bile ,Hepatectomy ,Humans ,Medicine ,In patient ,Bile leak ,Aged ,business.industry ,Perioperative ,Middle Aged ,Plastic Surgery Procedures ,United States ,030220 oncology & carcinogenesis ,Concomitant ,Female ,Surgery ,business ,Complication ,Major hepatectomy - Abstract
BACKGROUND: Despite technical advances, bile leak remains a significant complication after hepatectomy. The current study uses a targeted multi-institutional dataset to characterize perioperative factors that are associated with bile leakage after hepatectomy and to better understand the impact of bile leak on morbidity and mortality. METHODS: Adult patients in the 2014–2015 ACS NSQIP targeted hepatectomy dataset were linked to the ACS NSQIP PUF dataset. Bivariable and multivariable regression analyses were used to assess the associations between clinical factors and post-hepatectomy bile leak. RESULTS: Of 6,859 patients, 530 (7.7%) had a postoperative bile leak. Proportion of bile leaks was significantly higher in patients after major compared to minor hepatectomy (12.6% vs 5.1%, p
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- 2017
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7. Unplanned Reoperation Following Colorectal Surgery: Indications and Operations
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Matthew G. Mullen, Florence E. Turrentine, Christopher A. Guidry, Traci L. Hedrick, Elizabeth D. Krebs, Charles M. Friel, and Alex D. Michaels
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Male ,Reoperation ,medicine.medical_specialty ,Multivariate analysis ,Colon ,medicine.medical_treatment ,Operative Time ,Rectum ,Anastomotic Leak ,Anastomosis ,Article ,03 medical and health sciences ,0302 clinical medicine ,Adrenal Cortex Hormones ,Risk Factors ,medicine ,Humans ,Digestive System Surgical Procedures ,Retrospective Studies ,business.industry ,General surgery ,Malnutrition ,Gastroenterology ,Retrospective cohort study ,Bowel resection ,Middle Aged ,medicine.disease ,Colorectal surgery ,Surgery ,Bowel obstruction ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Female ,030211 gastroenterology & hepatology ,Functional status ,Emergencies ,business ,Intestinal Obstruction - Abstract
Prior studies have demonstrated a reoperation rate ranging from 5.8 to 7.6% following colorectal surgery. However, the indications for reoperation have not been extensively evaluated. We aimed to describe the indications for reoperation and associated procedures following colorectal resection. This is a retrospective cohort study of all patients undergoing colorectal resection at a single institution from 2003 to 2013. For patients who returned to the operating room, the primary indication was categorized into mutually exclusive categories and all procedures performed within 30 days of the initial operation were indexed. Univariate and multivariate analyses were performed. We identified 2793 patients who underwent colorectal operations, of which 407 (14.6%) were emergent. A total of 178 (6.7%) patients returned to the operating room. On multivariate analysis, emergent operation, malnutrition, corticosteroid use, and operative duration were independently associated with reoperation; independent functional status was protective. The most common indications for reoperation were anastomotic leak and bowel obstruction. The most common procedures performed were ostomy creation, bowel resection, and adhesiolysis. Reoperation after colorectal surgery is a relatively common occurrence for which we have identified the risk factors, most common indications, and specific procedures performed. This knowledge will help identify areas for improvement.
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- 2017
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8. Patient Reported Outcomes 10 years After Roux-en-Y Gastric Bypass
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Florence E. Turrentine, Matthew G. Mullen, James H. Mehaffey, Rachel L. Mehaffey, Peter T. Hallowell, and Bruce D. Schirmer
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Adult ,Male ,medicine.medical_specialty ,Time Factors ,Long term follow up ,Endocrinology, Diabetes and Metabolism ,Gastric bypass ,Gastric Bypass ,030209 endocrinology & metabolism ,03 medical and health sciences ,0302 clinical medicine ,Patient satisfaction ,Weight loss ,Weight Loss ,Humans ,Medicine ,Patient Reported Outcome Measures ,030212 general & internal medicine ,Nutrition and Dietetics ,business.industry ,Lived experience ,Middle Aged ,Roux-en-Y anastomosis ,Obesity, Morbid ,Surgery ,Treatment Outcome ,Patient Satisfaction ,Female ,Self Report ,medicine.symptom ,business ,Follow-Up Studies - Abstract
Following weight-loss surgery, patients who failed to achieve or sustain weight loss have nevertheless reported high satisfaction with their long-term bariatric experience. Understanding this phenomenon better will likely improve patients' experiences.The purpose of this study was to explore patients' long-term experiences following bariatric surgery.A 604-bed academic health system in the USA.Participants rated satisfaction and shared spontaneous comments regarding their gastric bypass experience. A phenomenological mode of inquiry explored participants' experiences. Transcribed phrases were categorized and themes identified.In a 2004 surgical cohort, with 55% (155/281) participation, 99% of participants rated bariatric experience satisfaction (mean score 8.4) and 74% (115/155) shared comments regarding experiences. Responses were categorized as positive (63% 72/115), neutral (25% 29/115), or negative (12% 14/115). Satisfaction, Appreciation, and Gratefulness emerged as themes from positive comments, with 8% (6/72) explicitly acknowledging amount of weight loss achieved. Twenty-five percent (18/72) spontaneously mentioned undergoing surgery again or recommending the procedure to others. Neutral comments contained the themes of Reflection, Acknowledgment, and Wistfulness. Themes of Dissatisfaction, Disappointment, and Regret emerged from negative comments. Forty-three percent (6/14) of negative comments remarked on regaining weight or not reaching goal weight. Twenty-one percent (3/14) of negative comments explicitly stated regret at having undergone surgery.Participants readily shared comments regarding their gastric bypass experience. Exploring themes provided insight into patients' satisfaction with bariatric surgery even when weight-loss goals were not met and conversely substantial dissatisfaction even when weight loss occurred. This study underscores the importance of understanding the patients' long-term experience following bariatric surgery.
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- 2017
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9. Nutrient Deficiency 10 Years Following Roux-en-Y Gastric Bypass: Who’s Responsible?
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Mathew G. Mullen, Andrew M.D. Wolf, Steven K. Malin, Rachel L. Mehaffey, Peter T. Hallowell, Bruce D. Schirmer, Florence E. Turrentine, and J. Hunter Mehaffey
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Adult ,Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Gastric bypass ,Population ,Gastric Bypass ,Aftercare ,Bariatric Surgery ,030209 endocrinology & metabolism ,Comorbidity ,Logistic regression ,Article ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Humans ,Medicine ,Micronutrients ,education ,education.field_of_study ,Nutrition and Dietetics ,business.industry ,Malnutrition ,Primary care physician ,Vitamins ,Middle Aged ,medicine.disease ,Roux-en-Y anastomosis ,Obesity, Morbid ,Surgery ,Cross-Sectional Studies ,Logistic Models ,Dietary Supplements ,Female ,Laparoscopy ,030211 gastroenterology & hepatology ,business ,Nutrient deficiency ,Multivitamin ,Blood Chemical Analysis - Abstract
Monitoring and prevention of long-term nutrient deficiency after laparoscopic Roux-en-Y gastric bypass (LRYGB) remains ill defined due to limited surgical follow-up after bariatric surgery. This study compared nutrient supplementation as well as surgeon and primary care physician (PCP) follow-up between patients with short-term versus long-term follow-up. All patients undergoing LRYGB at a single institution in 2004 (long-term group, n = 281) and 2012–2013 (short-term group, n = 149) were evaluated. Prospectively collected database, electronic medical record (EMR) review and telephone survey were used to obtained follow-up for both cohorts. Multivariate logistic regression was used to assess factors independently predicting multivitamin use. Complete follow-up was achieved in 172 (61 %) long-term and 107 (72 %) short-term patients. We demonstrate a significant difference (p
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- 2017
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10. Morbidity and Mortality After Gastrectomy: Identification of Modifiable Risk Factors
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Allison N. Martin, Florence E. Turrentine, Deepanjana Das, Victor M. Zaydfudim, Reid B. Adams, and Todd W. Bauer
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Male ,Reoperation ,medicine.medical_specialty ,medicine.medical_treatment ,030230 surgery ,Patient Readmission ,Article ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Gastrectomy ,Risk Factors ,mental disorders ,medicine ,Humans ,Gastric resection ,Intubation, Gastrointestinal ,Aged ,Retrospective Studies ,business.industry ,General surgery ,Malnutrition ,Smoking ,Age Factors ,Gastroenterology ,Transfusion Reaction ,Perioperative ,Middle Aged ,Acs nsqip ,030220 oncology & carcinogenesis ,Female ,Surgery ,business - Abstract
Morbidity after gastrectomy remains high. The potentially modifiable risk factors have not been well described. This study considers a series of potentially modifiable patient-specific and perioperative characteristics that could be considered to reduce morbidity and mortality after gastrectomy.This retrospective cohort study includes adults in the ACS NSQIP PUF dataset who underwent gastrectomy between 2011 and 2013. Sequential multivariable models were used to estimate effects of clinical covariates on study outcomes including morbidity, mortality, readmission, and reoperation.Three thousand six hundred and seventy-eight patients underwent gastrectomy. A majority of patients had distal gastrectomy (N = 2,799, 76.1 %) and had resection for malignancy (N = 2,316, 63.0 %). Seven hundred and ninety-eight patients (21.7 %) experienced a major complication. Reoperation was required in 290 patients (7.9 %). Thirty-day mortality was 5.2 %. Age (OR = 1.01, 95 % CI = 1.01-1.02, p = 0.001), preoperative malnutrition (OR = 1.65, 95 % CI = 1.35-2.02, p 0.001), total gastrectomy (OR = 1.63, 95 % CI = 1.31-2.03, p 0.001), benign indication for resection (OR = 1.60, 95 % CI = 1.29-1.97, p 0.001), blood transfusion (OR = 2.57, 95 % CI = 2.10-3.13, p 0.001), and intraoperative placement of a feeding tubes (OR = 1.28, 95 % CI = 1.00-1.62, p = 0.047) were independently associated with increased risk of morbidity. Association between tobacco use and morbidity was statistically marginal (OR = 1.23, 95 % CI = 0.99-1.53, p = 0.064). All-cause postoperative morbidity had significant associations with reoperation, readmission, and mortality (all p 0.001).Mitigation of perioperative risk factors including smoking and malnutrition as well as identified operative considerations may improve outcomes after gastrectomy. Postoperative morbidity has the strongest association with other measures of poor outcome: reoperation, readmission, and mortality.
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- 2016
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11. Type 2 diabetes remission following gastric bypass: does diarem stand the test of time?
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Steven K. Malin, J. Hunter Mehaffey, Bruce D. Schirmer, Florence E. Turrentine, Rachel L. Mehaffey, Peter T. Hallowell, Mathew G. Mullen, and Jennifer L. Kirby
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Adult ,Male ,medicine.medical_specialty ,Databases, Factual ,Gastric bypass ,Gastric Bypass ,030209 endocrinology & metabolism ,Type 2 diabetes ,Gastroenterology ,Article ,Decision Support Techniques ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Diabetes mellitus ,medicine ,Health Status Indicators ,Humans ,030212 general & internal medicine ,Aged ,Retrospective Studies ,Aged, 80 and over ,business.industry ,nutritional and metabolic diseases ,Type 2 Diabetes Mellitus ,Retrospective cohort study ,Middle Aged ,Hepatology ,medicine.disease ,Obesity ,Surgery ,Treatment Outcome ,Diabetes Mellitus, Type 2 ,Female ,business ,Follow-Up Studies ,Abdominal surgery - Abstract
Roux-en-Y Gastric Bypass (RYGB) is well known to ameliorate type 2 diabetes mellitus (T2DM), and recent work suggests that the preoperative DiaREM model predicts successful remission up to 1 year post-RYGB. However, no data exist for long-term validity. Therefore, we sought to determine the utility of this score on long-term RYGB effectiveness for T2DM resolution at 2 and 10 years, respectively. T2DM patients (Age: 48, BMI: 49, HbA1C: 8.1) undergoing RYGB at the University of Virginia between 2004–2006 (n = 42) and 2012–2014 (n = 59) were evaluated prospectively to assess preoperative DiaREM score, defined from insulin use, age, HbA1C, and type of antidiabetic medication. T2DM partial remission status was based on the American Diabetes Association guidelines (HbA1C
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- 2016
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12. Crew resource management training for surgeons: feasibility and impact
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Stephanie Guerlain, Florence E. Turrentine, J. Forrest Calland, David T. Bauer, and Reid B. Adams
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Medical education ,Knowledge management ,business.industry ,Debriefing ,education ,Psychological intervention ,Crew resource management ,Computer Science Applications ,Human-Computer Interaction ,Philosophy ,Patient safety ,Medicine ,Industrial and organizational psychology ,business ,Baseline (configuration management) - Abstract
This paper describes a prospective, within-subjects study to measure the before-after effect of training five general surgery attendings on crew resource management (CRM) strategies on the resultant use and perceived utility of those strategies. Subjects were trained via a 1-h lecture on seven CRM skills after their second observed case, and participated in a 15 min debriefing with the trainers immediately following their fourth through sixth observed cases. These interventions led to a significant increase in frequency (by 26–70%) of preoperative briefing elements over baseline. There was a significant correlation between the use of CRM practices and their perceived utility in improving team coordination and reducing error.
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- 2007
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