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225 results on '"Gan, Lin"'

1. Clathrin mediates membrane fission and budding by constricting membrane pores

Author

Wei, Lisi, primary, Guo, Xiaoli, additional, Haimov, Ehud, additional, Obashi, Kazuki, additional, Lee, Sung Hoon, additional, Shin, Wonchul, additional, Sun, Min, additional, Chan, Chung Yu, additional, Sheng, Jiansong, additional, Zhang, Zhen, additional, Mohseni, Ammar, additional, Ghosh Dastidar, Sudhriti, additional, Wu, Xin-Sheng, additional, Wang, Xin, additional, Han, Sue, additional, Arpino, Gianvito, additional, Shi, Bo, additional, Molakarimi, Maryam, additional, Matthias, Jessica, additional, Wurm, Christian A., additional, Gan, Lin, additional, Taraska, Justin W., additional, Kozlov, Michael M., additional, and Wu, Ling-Gang, additional

Published
2024
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3. Associated lifestyle factors of elevated plasma aldosterone concentration in community population, gender-stratified analysis of a cross-sectional survey

Author

Maitituersun, Adalaiti, primary, Heizhati, Mulalibieke, additional, Li, Nanfang, additional, Gan, Lin, additional, Li, Mei, additional, Yao, Ling, additional, Yang, Wenbo, additional, Liu, Shasha, additional, Aierken, Xiayire, additional, Wang, Hui, additional, Liu, Miaomiao, additional, Hong, Jing, additional, Wu, Ting, additional, Zhang, Delian, additional, and Zhu, Qing, additional

Published
2024
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8. Detecting and quantifying Veillonella by real-time quantitative PCR and droplet digital PCR

Author

Ding, Zanbo, primary, Cui, Jinghua, additional, Zhang, Qun, additional, Feng, Junxia, additional, Du, Bing, additional, Xue, Guanhua, additional, Yan, Chao, additional, Gan, Lin, additional, Fan, Zheng, additional, Feng, Yanling, additional, Zhao, Hanqing, additional, Xu, Ziying, additional, Yu, Zihui, additional, Fu, Tongtong, additional, Zhang, Rui, additional, Cui, Xiaohu, additional, Tian, Ziyan, additional, Chen, Jinfeng, additional, Chen, Yujie, additional, Li, Zhoufei, additional, Zhong, Xuemei, additional, Lin, Yanbing, additional, and Yuan, Jing, additional

Published
2024
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10. Accelerating multielectron reduction at CuxO nanograins interfaces with controlled local electric field

Author

Guo, Weihua, primary, Zhang, Siwei, additional, Zhang, Junjie, additional, Wu, Haoran, additional, Ma, Yangbo, additional, Song, Yun, additional, Cheng, Le, additional, Chang, Liang, additional, Li, Geng, additional, Liu, Yong, additional, Wei, Guodan, additional, Gan, Lin, additional, Zhu, Minghui, additional, Xi, Shibo, additional, Wang, Xue, additional, Yakobson, Boris I., additional, Tang, Ben Zhong, additional, and Ye, Ruquan, additional

Published
2023
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16. A novel phage carrying capsule depolymerase effectively relieves pneumonia caused by multidrug-resistant Klebsiella aerogenes

Author

Cui, Xiaohu, primary, Du, Bing, additional, Feng, Junxia, additional, Feng, Yanling, additional, Fan, Zheng, additional, Chen, Jinfeng, additional, Cui, Jinghua, additional, Gan, Lin, additional, Fu, Tongtong, additional, Tian, Ziyan, additional, Zhang, Rui, additional, Yan, Chao, additional, Zhao, Hanqing, additional, Xu, Wenjian, additional, Xu, Ziying, additional, Yu, Zihui, additional, Ding, Zanbo, additional, Li, Zhoufei, additional, Chen, Yujie, additional, Xue, Guanhua, additional, and Yuan, Jing, additional

Published
2023
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19. Bacteriophage targeting microbiota alleviates non-alcoholic fatty liver disease induced by high alcohol-producing Klebsiella pneumoniae

Author

Gan, Lin, primary, Feng, Yanling, additional, Du, Bing, additional, Fu, Hanyu, additional, Tian, Ziyan, additional, Xue, Guanhua, additional, Yan, Chao, additional, Cui, Xiaohu, additional, Zhang, Rui, additional, Cui, Jinghua, additional, zhao, Hanqing, additional, Feng, Junxia, additional, Xu, Ziying, additional, Fan, Zheng, additional, Fu, Tongtong, additional, Du, Shuheng, additional, Liu, Shiyu, additional, Zhang, Qun, additional, Yu, Zihui, additional, Sun, Ying, additional, and Yuan, Jing, additional

Published
2023
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20. The genetic spectrum of a cohort of patients clinically diagnosed as Parkinson’s disease in mainland China

Author

Sun, Yi-Min, primary, Zhou, Xin-Yue, additional, Liang, Xiao-Niu, additional, Lin, Jin-Ran, additional, Xu, Yi-Dan, additional, Chen, Chen, additional, Wei, Si-Di, additional, Chen, Qi-Si, additional, Liu, Feng-Tao, additional, Zhao, Jue, additional, Tang, Yi-Lin, additional, Shen, Bo, additional, Gan, Lin-Hua, additional, Lu, Boxun, additional, Ding, Zheng-Tong, additional, An, Yu, additional, Wu, Jian-Jun, additional, and Wang, Jian, additional

Published
2023
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21. Ultrafast charge transfer in mixed-dimensional WO3-x nanowire/WSe2 heterostructures for attomolar-level molecular sensing

Author

Lv, Qian, primary, Tan, Junyang, additional, Wang, Zhijie, additional, Gu, Peng, additional, Liu, Haiyun, additional, Yu, Lingxiao, additional, Wei, Yinping, additional, Gan, Lin, additional, Liu, Bilu, additional, Li, Jia, additional, Kang, Feiyu, additional, Cheng, Hui-Ming, additional, Xiong, Qihua, additional, and Lv, Ruitao, additional

Published
2023
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23. A Novel Quantitative Electrocardiography Strategy Reveals the Electroinhibitory Effect of Tamoxifen on the Mouse Heart

Author

Xie, Ming, primary, Zhu, Shuoji, additional, Liu, Gang, additional, Wu, Yijin, additional, Zhou, Wenkai, additional, Yu, Dingdang, additional, Wan, Jinkai, additional, Xing, Shenghui, additional, Wang, Siqing, additional, Gan, Lin, additional, Li, Ge, additional, Chang, Dehua, additional, Lai, Hao, additional, Liu, Nanbo, additional, and Zhu, Ping, additional

Published
2023
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24. Prevalence of primary aldosteronism in patients with concomitant hypertension and obstructive sleep apnea, baseline data of a cohort

Author

Heizhati, Mulalibieke, primary, Aierken, Xiayire, additional, Gan, Lin, additional, Lin, Mengyue, additional, Luo, Qin, additional, Wang, Menghui, additional, Hu, Junli, additional, Maimaiti, Nuerguli, additional, Duiyimuhan, Gulinuer, additional, Yang, Wenbo, additional, Yao, Ling, additional, Zhu, Qing, additional, and Li, Nanfang, additional

Published
2023
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26. A pure nanoICG-based homogeneous lipiodol formulation: toward precise surgical navigation of primary liver cancer after long-term transcatheter arterial embolization

Author

Yang Zhang, Hongwei Cheng, Hu Chen, Peiyao Xu, En Ren, Yonghe Jiang, Dengfeng Li, Xing Gao, Yating Zheng, Pan He, Huirong Lin, Biaoqi Chen, Gan Lin, Aizheng Chen, Chengchao Chu, Jingsong Mao, and Gang Liu

Subjects
Indocyanine Green, Carcinoma, Hepatocellular, Ethiodized Oil, Surgery, Computer-Assisted, Liver Neoplasms, Optical Imaging, Animals, Humans, Nanoparticles, Radiology, Nuclear Medicine and imaging, Rabbits, General Medicine, Embolization, Therapeutic
Abstract

To surmount the critical issues of indocyanine green (ICG), and thus achieving a precise surgical navigation of primary liver cancer after long-term transcatheter arterial embolization.In this study, a facile and green pure-nanomedicine formulation technology is developed to construct carrier-free indocyanine green nanoparticles (nanoICG), and which subsequently dispersed into lipiodol via a super-stable homogeneous lipiodol formulation technology (SHIFT nanoICG) for transcatheter arterial embolization combined near-infrared fluorescence-guided precise hepatectomy.SHIFT nanoICG integrates excellent anti-photobleaching capacity, great optical imaging property, and specific tumoral deposition to recognize tumor regions, featuring entire-process enduring fluorescent-guided precise hepatectomy, especially in resection of the indiscoverable satellite lesions (0.6 mm × 0.4 mm) in rabbit bearing VX2 orthotopic hepatocellular carcinoma models.Such a simple and effective strategy provides a promising avenue to address the clinical issue of clinical hepatectomy and has excellent potential for a translational pipeline.

Published
2021

29. Generation and comparative analysis of an Itga8-CreERT2 mouse with preferential activity in vascular smooth muscle cells

Author

Warthi, Ganesh, primary, Faulkner, Jessica L., additional, Doja, Jaser, additional, Ghanam, Amr R., additional, Gao, Pan, additional, Yang, Allison C., additional, Slivano, Orazio J., additional, Barris, Candee T., additional, Kress, Taylor C., additional, Zawieja, Scott D., additional, Griffin, Susan H., additional, Xie, Xiaoling, additional, Ashworth, Alan, additional, Christie, Christine K., additional, Bryant, William B., additional, Kumar, Ajay, additional, Davis, Michael J., additional, Long, Xiaochun, additional, Gan, Lin, additional, Belin de Chantemèle, Eric J., additional, Lyu, Qing R., additional, and Miano, Joseph M., additional

Published
2022
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34. A classification scheme for Earth’s critical zones and its application in China

Author

Gan-Lin Zhang, Kening Wu, and Xiaodong Song

Subjects
Driving factors, geography, geography.geographical_feature_category, Land use, Sustainable management, Earth science, Bedrock, Spatial ecology, General Earth and Planetary Sciences, Environmental science, Spatial distribution, Natural resource, Critical Zone Observatories
Abstract

As the thin layer at the Earth’s terrestrial surface, the critical zone (CZ) ranges from the vegetation canopy to the aquifer or the interface between saprolite and bedrock and varies greatly in space. In the last decade, much attention has been paid to the establishment of Critical Zone Observatories (CZOs) that focus on various aspects of CZ science over different time scales. However, to the best of our knowledge, few studies have explicitly contributed to CZ classification or regionalization; thus, the spatial patterns of similar CZs have not been clearly identified. This study proposed a three-category CZ classification scheme by integrating environmental factors that greatly affect the transfer of energy and mass in the Earth’s near-surface environment and thus dominate CZ formation and evolution, i.e., climate, parent material, soil type, groundwater table depth, geomorphology and land use. The main goal was to highlight the zonality of these driving forces, of which the high-category classification units were overlaid to delineate the CZ boundaries. The CZ regionalization of China was performed as a case study, resulting in 44 major regions (1st category), 100 submajor regions (2nd category) and 1448 regions (3rd category). The spatial distributions and driving factors of the ten largest regions were identified, followed by a simple comparison of the CZO network. Then, the proposed CZ regionalization was compared with recent studies on regionalization in China to evaluate its successes and weaknesses. By linking together CZ studies from the last decade, we advocate that a theoretical framework integrating the CZ evolution processes with ecological functions acts as one of the frontiers of CZ science. Our study demonstrates that the proposed three-category CZ classification scheme effectively identifies the spatial variations in CZs and could thus be further applied in other areas to advance terrestrial environmental research and provide decision support for the sustainable management of natural resources.

Published
2021

37. Overcoming addition of phosphoethanolamine to lipid A mediated colistin resistance in Acinetobacter baumannii clinical isolates with colistin–sulbactam combination therapy

Author

Srisakul, Sukrit, primary, Wannigama, Dhammika Leshan, additional, Higgins, Paul G., additional, Hurst, Cameron, additional, Abe, Shuichi, additional, Hongsing, Parichart, additional, Saethang, Thammakorn, additional, Luk-in, Sirirat, additional, Liao, Tingting, additional, Kueakulpattana, Naris, additional, Shein, Aye Mya Sithu, additional, Gan, Lin, additional, Kupwiwat, Rosalyn, additional, Tanasatitchai, Chanikan, additional, Wapeesittipan, Pattama, additional, Phattharapornjaroen, Phatthranit, additional, Badavath, Vishnu Nayak, additional, Leelahavanichkul, Asada, additional, and Chatsuwan, Tanittha, additional

Published
2022
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42. Stoichiometric relations of C, N, and P in urban top soils in Nanjing, China, and their biogeochemical implications

Author

Jin-Ling Yang, Da-Gang Yuan, Yu-Guo Zhao, Gan-Lin Zhang, and Yue He

Subjects
education.field_of_study, Biogeochemical cycle, geography, geography.geographical_feature_category, Soil test, Stratigraphy, Population, 04 agricultural and veterinary sciences, 010501 environmental sciences, Urban area, 01 natural sciences, Environmental chemistry, Soil water, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, Environmental science, education, Eutrophication, Cycling, Surface water, 0105 earth and related environmental sciences, Earth-Surface Processes
Abstract

With increasing urban area and population, global cities are playing a more important role in the alteration of the global biogeochemical cycles. The aims of this study are to understand the concentrations and stoichiometric relations of biogenic elements (C, N, and P) in urban soils, further to reveal the effects of C, N, and P accumulation on the urban environment. We collected 317 surface (0–10 cm) soil samples taken from Nanjing, China, a typical city with more than 2000 years of history. These soil samples were located in different urban zones of Nanjing with different land use histories. The soil C, N, and P concentrations were determined. The stoichiometric relations of soil C, N, and P were investigated in urban soils. Meanwhile, some studies on sources of C, N, and P in diverse urban settings from literature were combined to explore the universal rule of C, N, and P cycling and their ecological and environmental effects in urban area. Compared to rural soils, more C, N, and P are accumulated in the urban soils, which also change their stoichiometric relations. The concentrations of OC, TN, and TP in urban top soils are 17.0 ± 9.69 g kg−1, 1.53 ± 0.92 g kg−1, and 1.31 ± 0.67 g kg−1, respectively. The mean atomic ratio of C:N:P is 37:3:1 in the surface of urban soils that strictly differs from natural soils in China and the whole world. The mean of C:N ratio in urban soils is similar to that of agriculture, grassland, and forest soils. However, the ratios of C:P and N:P in urban soils are much lower than that in agricultural, forest, and grassland soils. This implies that P is extremely enriched in the urban soils. The high C in urban soils are considered coming from natural and anthropogenic sources. The high N and P mainly come from anthropogenic sources. The well-constrained C:N:P ratio in rural soils does not apply for urban soils. The abnormal C:N:P ratio of urban soils is the result of unbalanced accumulation of C, N, and P from human activities. Urban soils are already an important storage of carbon. High N and P in urban soils may bring threat of surface water eutrophication and ground water contamination. These effects are expected to increase with the city development time.

Published
2020

46. Huayu Pill (化瘀丸) Promotes Fluorescent Doxorubicin Delivery to Tumors in Mouse Model of Lung Cancer

Author

Ke-Xin Cao, Lei Gao, Gan-Lin Zhang, Cai-Xia Hao, Xue-Man Ma, Guo-Wang Yang, Mingwei Yu, Xiaomin Wang, and Qi-Wei Li

Subjects
Chemotherapy, business.industry, medicine.medical_treatment, 0211 other engineering and technologies, 02 engineering and technology, General Medicine, Blood flow, medicine.disease, 030226 pharmacology & pharmacy, In vitro, Metastasis, 03 medical and health sciences, Regimen, 0302 clinical medicine, Complementary and alternative medicine, 021105 building & construction, Drug delivery, Cancer research, medicine, Pharmacology (medical), Doxorubicin, business, Lung cancer, medicine.drug
Abstract

Objective: To study the effect and mechanism of Huayu Wan (化瘀丸, HYW) in combination of chemotherapy of tumor treatment. Methods: HYW serum was added in Lewis cells to assess its impact on fluorescent doxorubicin delivery in vitro. Then, Lewis tumor cells was implanted in C57BL/6 mice via xenograft transplantation. Tumor growth was measured and signal intensity corresponding to blood flow was assessed by laser doppler perfusion imaging (LDPI). Finally, the effect of HYW on the effificacy of doxorubicin was studied. Results: HYW can improve the transfer of fluorescent doxorubicin into cells. The blood flow signal in the tumor tissues of the HYW group was higher than that of the control group (P

Published
2020

47. A chronosequence study of purple paddy soils with respect to improving ammonium and potassium fertilization management

Author

Fan Yang, Gan-Lin Zhang, Guang-Zhong Han, and Laiming Huang

Subjects
Chemistry, Stratigraphy, Potassium, Potash, chemistry.chemical_element, 04 agricultural and veterinary sciences, 010501 environmental sciences, engineering.material, Hydroponics, 01 natural sciences, chemistry.chemical_compound, Adsorption, Environmental chemistry, Soil water, 040103 agronomy & agriculture, engineering, 0401 agriculture, forestry, and fisheries, Ammonium, Fertilizer, Clay minerals, 0105 earth and related environmental sciences, Earth-Surface Processes
Abstract

Purple paddy soils cover about 66% of the paddy soils in Sichuan Basin. Complex interactions made the effects of potassium fertilizer application on NH4+ adsorption more complicated and the behavior of NH4+ and K+ interaction in purple paddy soils has rarely been evaluated. We hypothesize that correct management of these soils can enhance the efficiency of ammonium and potassium fertilizers. In order to determine correct management methods, it is important to understand the interaction of main nutrient cations NH4+ and K+ and maturation hydroponics in purple paddy soils with different paddy cultivation times. A purple paddy soil chronosequence with cultivation history from 0 to 300 years was studied to understand the respective effects of SOM and mineralogy on NH4+ and K+ sorption behavior by adsorption experiments using samples both before and after H2O2 oxidation. The study shows that maturation hydroponics influenced NH4+ and K+ adsorption mainly through changing clay mineralogy and enhancing SOM accumulation. SOM and smectite play positive effects for NH4+ adsorption. The K+ adsorption, however, is mainly affected by the smectite changes. The adsorption percentages are obviously higher at 25–50 mg L−1 for each NH4+ solution and higher at 50–100 mg L−1 for each K+ solution. When ammonium and potassium were applied together, NH4+ and K+ adsorption are mutually weakened. In addition, the percentage of K+ adsorption increased from 49.7–57.7% for the 100 mg L−1 K+ solution to 50.9–58.5% for the 200 mg L−1 K+ solution at 200 mg L−1 of added NH4+. SOM enrichments could be a positive way to improve the ammonium fertilizer utilization efficiency in purple paddy soils. Potassium may be more vulnerable to loss at low K+ concentrations given that ammonium and potassium fertilizers were applied together and it should be separately applied to enhance the utilization efficiency of applied fertilizer.

Published
2020

48. Metal-organic frameworks nanoswitch: Toward photo-controllable endo/lysosomal rupture and release for enhanced cancer RNA interference

Author

Xiaoyuan Chen, Ye Tian, Gang Liu, Peng Mi, Shangui Tang, Wen Cai, Chengchao Chu, Yang Zhang, Gan Lin, JiaJing Zhou, Junqing Wang, and Long Zhang

Subjects
Small interfering RNA, Cancer therapy, 02 engineering and technology, Gene delivery, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, Anticancer drug, Atomic and Molecular Physics, and Optics, 0104 chemical sciences, chemistry.chemical_compound, chemistry, RNA interference, Biophysics, General Materials Science, Metal-organic framework, Electrical and Electronic Engineering, 0210 nano-technology, DNA
Abstract

Endo/lysosomal escape and gene release are two critical bottlenecks in gene delivery. Herein, a novel photo-controllable metal-organic frameworks (MOFs) nanoswitch is rationally designed for enhancing small interfering RNA (siRNA) delivery. One single laser triggers the “off-to-on” switching of MOFs nanocomplexes, inducing significant siRNA release accompanied by rapid MOFs dissociation into protonatable 2-methylimidazalo and osmotic rupturing Zn2+ ions, which cooperatively contribute to remarkable endo/lysosomal rupture (∼ 90%). The simultaneous endo/lysosomal rupture and release enable a high spatio-temporal control on RNA interference for effective cancer therapy. Notably, the “off-to-on” switching also activates fluorescence recovery for real-time monitoring siRNA delivery. The nanoswitch could easily be extended to deliver other therapeutic agents (e.g., DNA, protein, anticancer drug) for overcoming endo/lysosomal entrapment.

Published
2020

49. Lifetime measurements in $$^{138}$$Nd

Author

Tian-Xiao Li, Bao-Ji Zhu, Yan-Xiang Gao, Shi-Peng Hu, Zheng-Xin Wu, Cong-Bo Li, Yun Zheng, Yan-Jun Jin, Ke-Yan Ma, Jian Zhong, Hui-Bin Sun, Qi Luo, Dong Yang, Qiwen Fan, Xiao-Guang Wu, Guangsheng Li, Gan Lin, Yingjun Ma, and Hai-Ge Zhao

Subjects
Physics, Nuclear and High Energy Physics, Recoil, Nuclear Energy and Engineering, Atomic physics, Decay curve
Abstract

Lifetimes of the 2 $$_1^{+}$$ , 4 $$_1^{+}$$ , 7 $$_2^{-}$$ , 10 $$_2^{+}$$ , 12 $$_2^{+}$$ , and 14 $$_1^{+}$$ states in $$^{138}$$ Nd populated via the $$^{123}$$ Sb( $$^{19}$$ F, 4n) $$^{138}$$ Nd fusion–evaporation reaction were measured with the recoil distance Doppler shift technique in combination with the differential decay curve method. The $$B(E2; 2_{1}^{+} \rightarrow 0_{1}^{+})$$ value fit well with the systematic trend in the Nd isotope chain and Grodzins rule, which proved that $$^{138}$$ Nd is a transitional nucleus.

Published
2021

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