1. Transthoracic 3D echocardiographic left heart chamber quantification in patients with bicuspid aortic valve disease
- Author
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Raluca G. Chelu, Annemien E. van den Bosch, Wim B. Vletter, Adriaan Coenen, Anthonie L. Duijnhouwer, Marcel L. Dijkshoorn, Jolien W. Roos-Hesselink, Vivan J.M. Baggen, Allard T. van den Hoven, Jackie S. McGhie, Cardiology, and Radiology & Nuclear Medicine
- Subjects
Left heart model ,Male ,Patient-Specific Modeling ,Aortic valve ,Software Validation ,Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] ,Echocardiography, Three-Dimensional ,Heart Valve Diseases ,030204 cardiovascular system & hematology ,Ventricular Function, Left ,030218 nuclear medicine & medical imaging ,Automation ,0302 clinical medicine ,Bicuspid aortic valve ,Bicuspid Aortic Valve Disease ,Prospective Studies ,Prospective cohort study ,Computed tomography ,Cardiac imaging ,Ejection fraction ,Models, Cardiovascular ,Stroke volume ,medicine.anatomical_structure ,Aortic Valve ,Predictive value of tests ,cardiovascular system ,Cardiology ,Atrial Function, Left ,Female ,Radiology ,Cardiology and Cardiovascular Medicine ,Adult ,medicine.medical_specialty ,Heart Ventricles ,Heart chamber ,Fully automated volumetric chamber quantification ,Young Adult ,03 medical and health sciences ,All institutes and research themes of the Radboud University Medical Center ,Predictive Value of Tests ,Internal medicine ,Image Interpretation, Computer-Assisted ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Heart Atria ,Original Paper ,3D echocardiography ,business.industry ,Stroke Volume ,medicine.disease ,Feasibility Studies ,Tomography, X-Ray Computed ,business - Abstract
Integration of volumetric heart chamber quantification by 3D echocardiography into clinical practice has been hampered by several factors which a new fully automated algorithm (Left Heart Model, (LHM)) may help overcome. This study therefore aims to evaluate the feasibility and accuracy of the LHM software in quantifying left atrial and left ventricular volumes and left ventricular ejection fraction in a cohort of patients with a bicuspid aortic valve. Patients with a bicuspid aortic valve were prospectively included. All patients underwent 2D and 3D transthoracic echocardiography and computed tomography. Left atrial and ventricular volumes were obtained using the automated program, which did not require manual contour detection. For comparison manual and semi-automated measurements were performed using conventional 2D and 3D datasets. 53 patients were included, in four of those patients no 3D dataset could be acquired. Additionally, 12 patients were excluded based on poor imaging quality. Left ventricular end-diastolic and end-systolic volumes and ejection fraction calculated by the LHM correlated well with manual 2D and 3D measurements (Pearson’s r between 0.43 and 0.97, p
- Published
- 2017
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