1. 12-week treadmill exercise program elicits lower energy availability without changes in serum testosterone in male rats
- Author
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Kelsey M. Mangano, Michael Dellogono, Thomas A. Wilson, Lyra R. Clark, and Erin E. Chenette
- Subjects
Serum testosterone ,medicine.medical_specialty ,business.industry ,Leptin ,030209 endocrinology & metabolism ,030229 sport sciences ,Lower energy ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Endurance training ,Internal medicine ,Male rats ,medicine ,Orthopedics and Sports Medicine ,Treadmill ,business ,Testosterone ,Hormone - Abstract
The purpose of this study was to investigate whether a treadmill endurance exercise program would reduce serum testosterone and leptin in male rats and assess the impact of increased dietary cholesterol on serum hormones. Male Sprague-Dawley Rats (n = 20) were randomly assigned to a control group (C) or an exercise training group (EX) that performed treadmill running 40 min/day, 6 days/week for 12 weeks. At study midpoint (week 6), rats were randomized to a high-cholesterol (HC) diet (n = 10) or remain on standard semi-purified (LC) diet (n = 10). Results are presented as median [IQR]. At end of week 6, EX + LC had significantly lower body weight (508 [460–527] vs 570 [516–606] g; p = 0.01), mean daily energy intake (76.3 [74.9–82.2] vs 90.9 [86.9–94.5] kcal; p
- Published
- 2018
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