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Start Over Descriptor "MESH: Brain Mapping" Publisher springer science and business media llc
2 results on '"MESH: Brain Mapping"'

1. Right temporal cerebral dysfunction heralds symptoms of acute mountain sickness

Author

Antoine Depaulis, Berend Feddersen, Soheyl Noachtar, Florian Thanbichler, Pritam Neupane, Robb Waanders, Harald Ausserer, Department of Neurology, Ludwig-Maximilians-Universität München (LMU)-Klinikum Grosshadern, Dynamique des Reseaux Neuronaux, Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Human Development and Community Services, Dept. of Neuropsychology, Landeskrankenhaus Rankweil, Collaboration, and Deransart, Colin

Subjects
Male, MESH: Mountaineering, Neurology, Ultrasonography, Doppler, Transcranial, Acclimatization, Hemodynamics, MESH: Respiratory Function Tests, Altitude Sickness, Electroencephalography, MESH: Carbon Dioxide, Functional Laterality, 0302 clinical medicine, MESH: Brain Mapping, Neuroradiology, MESH: Aged, Brain Mapping, MESH: Statistics, Nonparametric, MESH: Middle Aged, medicine.diagnostic_test, Altitude, MESH: Ultrasonography, Doppler, Transcranial, MESH: Cerebrovascular Circulation, Middle Aged, Effects of high altitude on humans, Temporal Lobe, Respiratory Function Tests, medicine.anatomical_structure, Cerebral blood flow, Cerebrovascular Circulation, Anesthesia, Acute Disease, Middle cerebral artery, MESH: Altitude Sickness, MESH: Acute Disease, Female, MESH: Oxygen, Adult, medicine.medical_specialty, Central nervous system, MESH: Acclimatization, Statistics, Nonparametric, 03 medical and health sciences, 030225 pediatrics, medicine.artery, MESH: Electroencephalography, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, medicine, Humans, MESH: Temporal Lobe, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Functional Laterality, Aged, MESH: Humans, business.industry, MESH: Adult, Carbon Dioxide, MESH: Altitude, MESH: Male, Mountaineering, Oxygen, Neurology (clinical), business, MESH: Female, 030217 neurology & neurosurgery
Abstract

International audience; Acute mountain sickness (AMS) can occur during climbs to high altitudes and may seriously disturb the behavioral and intellectual capacities of susceptible subjects. During a Himalayan expedition 32 mountaineers were examined with electroencephalography (EEG) and transcranial doppler sonography (TCD) to assess relative changes of middle cerebral artery velocity in relation to end-expiratory CO2 (EtCO2), peripheral saturation (SaO2), and symptoms of AMS. We tested the hypothesis that O2 desaturation and EtCO2 changes precede the development of AMS and result in brain dysfunction and compensatory mechanisms which can be measured by EEG and TCD, respectively. Contrary to our hypothesis, we found that subjects who later developed symptoms of AMS between 3,440 m and 5,050 m altitude exhibited an increase of slow cerebral activity in the right temporal region already at 3,440 m. Cerebral blood flow increased in these mountaineers in the right middle cerebral artery at 5,050 m. These findings indicate that regional brain dysfunction, which can be documented by EEG, heralds the appearance of clinical symptoms of AMS.

Published
2007
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2. Anatomy of verbal memory: a functional MRI study

Author

Samuel Dupont, Michel Baulac, D. Le Bihan, Yves Samson, Écologie fonctionnelle et physique de l'environnement (EPHYSE), Institut National de la Recherche Agronomique (INRA), Institut de recherche sur la biologie de l'insecte UMR7261 (IRBI), Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Cultures et Sociétés en Europe (CSE), Université Marc Bloch - Strasbourg II-Centre National de la Recherche Scientifique (CNRS), Service de Physique des Matériaux et Microstructures (SP2M - UMR 9002), Institut Nanosciences et Cryogénie (INAC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Service NEUROSPIN (NEUROSPIN), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, IFR de Neuroimagerie Fonctionnelle (IFR 49), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Human Brain Research Center [Kyoto] (HBRC), Kyoto University [Kyoto], Service Hospitalier Frédéric Joliot (SHFJ), Service de Neurologie [CHU Pitié-Salpêtrière], IFR70-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Cortex et Epilepsie [Paris], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Écologie fonctionnelle et physique de l'environnement (EPHYSE - UR1263), Université de Tours-Centre National de la Recherche Scientifique (CNRS), Université Grenoble Alpes (UGA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Service de neurologie 1 [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [APHP], Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), CHU Pitié-Salpêtrière [APHP]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Kyoto University, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), and Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP]

Subjects
Male, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, MESH: Mental Recall, Hippocampus, Brain mapping, MESH: Magnetic Resonance Imaging, 0302 clinical medicine, Medicine, MESH: Memory, Episodic memory, MESH: Brain Mapping, Cerebral Cortex, Brain Mapping, medicine.diagnostic_test, 05 social sciences, Verbal Learning, Magnetic Resonance Imaging, Temporal Lobe, Female, Occipital Lobe, Anatomy, MESH: Occipital Lobe, Adult, MESH: Hemodynamics, 050105 experimental psychology, Pathology and Forensic Medicine, 03 medical and health sciences, Memory, Functional neuroimaging, Humans, MESH: Temporal Lobe, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, Dominance, Cerebral, MESH: Humans, Recall, business.industry, Hemodynamics, MESH: Adult, Magnetic resonance imaging, MESH: Dominance, Cerebral, MESH: Verbal Learning, MESH: Cerebral Cortex, MESH: Male, MESH: Nerve Net, Mental Recall, Surgery, Nerve Net, Verbal memory, business, Functional magnetic resonance imaging, MESH: Female, Neuroscience, 030217 neurology & neurosurgery
Abstract

International audience; The recent advent of new functional neuroimaging techniques such as functional magnetic resonance imaging (fMRI) makes it possible to examine cerebral activations in healthy individuals. In the present study, we attempted to examine the anatomical distribution of neocortical and mediotemporal activations in control subjects during episodic memory tasks over 24 h. BOLD (blood oxygenation-level-dependent) fMRI data were collected from 10 control subjects. Twenty-two contiguous images covering the whole brain were acquired using an EPI echoplanar sequence. Subjects were instructed to learn a list of 17 words, and to recall it immediately and after a 24-h interval. Individual and group analyses were performed using SPM96. The results demonstrated that a similar left occipito-temporofrontal network was activated during both immediate and 24-h-delayed retrieval conditions. In addition, the 24-h-delayed retrieval also activated a larger parietal region and the right hippocampus. These findings suggest that fMRI is a reliable method with which to perform anatomical studies.

Published
2002
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