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Start Over Author "Mantovani V." Publisher springer science and business media llc
8 results on '"Mantovani V."'

1. MR Brain Screening in ADPKD Patients

Author

Capelli, I., primary, Zoli, M., additional, Righini, M., additional, Faccioli, L., additional, Aiello, V., additional, Spinardi, L., additional, Gori, D., additional, Friso, F., additional, Rustici, A., additional, Bortolotti, C., additional, Graziano, C., additional, Mantovani, V., additional, Sciascia, N., additional, Mazzatenta, D., additional, Seri, M., additional, Pastore Trossello, M., additional, and La Manna, G., additional

Published
2021
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6. Abstracts

Author

Brink, F. G., primary, Vaccari, Andrea, additional, Cugurra, Franco, additional, Mazzanti, L., additional, Crema, A., additional, Frigo, G. M., additional, Tacca, M., additional, Lecchini, S., additional, Beani, L., additional, Bianchi, C., additional, Gandini, A., additional, Lualdi, P., additional, Bella, D., additional, Rossini, L., additional, Sardi, A., additional, Baldoli, E., additional, Caravaggi, A. M., additional, Kyncl, J., additional, Mauz, G., additional, Kreye, V. A. W., additional, Tubaro, E., additional, Bulgini, M. J., additional, Biagi, G. L., additional, Barbaro, A. M., additional, Guerra, M. C., additional, Hümpel, J. -E., additional, Zetler, G., additional, Stern, P., additional, Bianco, P. L., additional, Fanciullacci, M., additional, Franchi, G., additional, Sicuteri, F., additional, Rovati, A. L., additional, Casula, P. L., additional, Meldolesi, J., additional, Angelucci, L., additional, Linari, G., additional, Soldani, G., additional, Pacini, S., additional, Pascale, V., additional, Mantovani, P., additional, Fregnan, G. B., additional, GlÄsser, A. H., additional, Jahrreiss, R., additional, Habermann, E., additional, Breithaupt, H., additional, Rübsamen, K., additional, Walsch, P., additional, Lankisch, P. G., additional, Vogt, W., additional, Rudinger, J., additional, Krejčí, I., additional, Pliška, V., additional, Poláček, I., additional, Möhring, J., additional, Brekner, Hanna, additional, Schömig, A., additional, Möhring, BÄrbel, additional, Philippu, A., additional, Przuntek, H., additional, Pecile, A., additional, Felici, M., additional, Müller, E. E., additional, Muller, E. E., additional, Cocchi, D., additional, Scapagnini, U., additional, Look, G. R., additional, Moberg, G. P., additional, Preziosi, P., additional, Ganong, W. F., additional, Fraschini, F., additional, Vargiu, L., additional, Spano, P. F., additional, Marquardt, H., additional, Zedeck, M. S., additional, Sternberg, S. S., additional, Fleisher, M., additional, Hamilton, L. D., additional, Classen, H. -G., additional, Marquardt, P., additional, SpÄth, M., additional, Schumacher, K. -A., additional, Bernauer, W., additional, Hahn, F., additional, Wissler, J., additional, Nimptsch, P., additional, Filipowski, P., additional, Gjuriš, V., additional, Wolf, D., additional, Moroni, F., additional, Buiatti, E., additional, Mannaioni, P. F., additional, Periti, P., additional, Lorenz, W., additional, Schauer, A., additional, Reimann, H. J., additional, Guidotti, A., additional, Meyer, R., additional, Doenicke, A., additional, Schmal, A., additional, Hutzel, M., additional, Werle, E., additional, Bertaccini, G., additional, Impicciatore, M., additional, Mossini, F., additional, Frontini, E., additional, Giani, G., additional, Nicolin, A., additional, Olivani, P., additional, Dietmann, K., additional, Schieck, A., additional, Kornalik, F., additional, Chiarra, A., additional, Piccinini, F., additional, Villani, F., additional, Caspary, W. F., additional, Nell, G., additional, Forth, W., additional, Overhoff, H., additional, Pfleger, K., additional, Rummel, W., additional, Agsten, M., additional, Voth, D., additional, Possner, R., additional, Förschler, M. -L., additional, KÄvenheim, W., additional, Kurz, H., additional, Wirth, K., additional, Bodem, G., additional, Dengler, H. J., additional, Rietbrock, N., additional, Plato, H. v., additional, Bergmann, K. v., additional, Abshagen, U., additional, Kewitz, H., additional, Hengstmann, J. H., additional, Konen, W., additional, Konen, C., additional, Backmann, H., additional, Haschemian, A., additional, Kemper, F., additional, Morgenroth, K., additional, Winterhoff, H., additional, Mascherpa, P., additional, Strauer, B. E., additional, Westberg, C., additional, Tauchert, M., additional, Juhran, W., additional, Ledda, F., additional, Giotti, A., additional, Turnheim, K., additional, Stühlinger, W., additional, Kraupp, O., additional, Trendelenburg, U., additional, Haeusler, G., additional, Brandt, W., additional, Reiter, M., additional, Nakamura, J., additional, Gerold, M., additional, Thoenen, H., additional, Boksay, I., additional, Bollmann, V., additional, Kukovetz, W. R., additional, Klein, W. W., additional, Pöch, G., additional, Lüdtke, A. H., additional, Braga, P. C., additional, Ferri, S., additional, Magnoni, V., additional, Romano, A., additional, Bartsch, W., additional, Heinz, N., additional, Furlanello, F., additional, Ferrari, M., additional, Sava, C., additional, Maragno, I., additional, Bergamaschi, M., additional, Fuccella, L. M., additional, Mandelli, V., additional, Tommasini, R., additional, Turba, C., additional, Usardi, M., additional, Lehr, E., additional, Gesmundo, F., additional, Susanna, A., additional, Paroli, E., additional, Carpi, A., additional, Cartoni, C., additional, Basso, P., additional, Giardini, V., additional, Marmo, E., additional, Brogi, M., additional, Bossa, R., additional, Fioroni, G., additional, Galatulas, I., additional, Pomarelli, P., additional, Henderson, P. Th., additional, Remmer, H., additional, Casals, J., additional, Petruch, F., additional, Schüppel, R., additional, Forti, G. Cantelli, additional, Fracasso, M. E., additional, Berti, T., additional, Maccari, M., additional, Gatti, M. T., additional, Losert, W., additional, Kraaz, W., additional, Jahn, P., additional, Rilke, A., additional, Cascio, G., additional, Mantia, G., additional, Leone, F., additional, Datz, B., additional, Vetter, J., additional, Brade, W., additional, Schönhöfer, P. S., additional, Skidmore, I. F., additional, Bourne, H. R., additional, Vapaatalo, H., additional, Bieck, P., additional, Westermann, E., additional, Stork, H., additional, Schmidt, F. H., additional, Riemenschneider, H., additional, Willig, F., additional, May, B., additional, Leinweber, W., additional, Poser, W., additional, Panten, U., additional, Hasselblatt, A., additional, Klissiunis, N., additional, Mykoniatis, M., additional, Lengsfeld, H., additional, Gey, K. F., additional, Bianchini, P., additional, Mantovani, V., additional, LoMarco, E., additional, Bufalina, L., additional, Guidi, G., additional, Osima, B., additional, Casetta, R., additional, Casarini, A., additional, Mann, E., additional, Pepeu, G., additional, Ruffi, A., additional, Mulas, A., additional, Pleul, O., additional, Lipparini, F., additional, Loizzo, A., additional, Carolis, Scotti, additional, Marino, A., additional, Girone, E., additional, Battista, O., additional, Marino, V., additional, Florio, V., additional, Longo, V. G., additional, Gogolák, G., additional, Stumpf, Ch., additional, Pavan, P., additional, Dross, K., additional, Bianchi, A., additional, Caprio, F., additional, Kuschinsky, K., additional, Carlo, R., additional, Mandel, P., additional, Rosa, M., additional, Willoughby, D. A., additional, Sorrentino, L., additional, Capasso, F., additional, Sandow, J., additional, Alpermann, H., additional, Metzger, H., additional, Vogel, H. G., additional, Velo, G. P., additional, Capelli, A., additional, Martinelli, G., additional, Bertoni, F., additional, Karzel, K., additional, Peters, H. D., additional, Hack, G., additional, Fleming, K., additional, Kazda, S., additional, Lamprecht, F., additional, Miksche, L., additional, Orth, H., additional, Philippi, A., additional, Schmidt, D., additional, Schneider, D., additional, Soell, G., additional, Taugner, R., additional, Hammersen, G., additional, Rosenthal, J., additional, Fülgraff, G., additional, Meiforth, A., additional, Sudhoff, D., additional, Zimmermann, E., additional, Knebel, L., additional, Barzaghi, F., additional, Riva, M., additional, Mantegazza, P., additional, Chiesara, E., additional, Edwards, K. D. G., additional, Morini, M., additional, Bilone, F., additional, Ortolani, L., additional, Barbieri, A., additional, Bertelli, A., additional, Cerrati, A., additional, Bizzi, A., additional, Codegoni, A. M., additional, Medea, A., additional, Tacconi, M. T., additional, Garattini, S., additional, Bonaccorsi, A., additional, Cotillo, P., additional, and Babulova, A., additional

Published
1971
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7. Glycosaminoglycan levels and structure in a mucopolysaccharidosis IIIA mice and the effect of a highly secreted sulfamidase engineered to cross the blood-brain barrier

Author

Nicola Volpi, Francesca Maccari, Fabio Galeotti, Veronica Mantovani, Alessandro Fraldi, Nc Sorrentino, Maccari, F., Sorrentino, N. C., Mantovani, V., Galeotti, F., Fraldi, A., and Volpi, N.

Subjects
0301 basic medicine, medicine.medical_specialty, Hydrolases, Mucopolysaccharidosis, Heparan sulfate, Hydrolase, Blood–brain barrier, Biochemistry, Dermatan sulfate, Glycosaminoglycan, Mice, Mucopolysaccharidosis III, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Internal medicine, medicine, Animals, Chondroitin sulfate, Mucopolysaccharidosis Type IIIA, Glycosaminoglycans, Animal, Engineered sulphamidase, Mucopolysaccharidoses IIIA, Sanfilippo, Chemistry, Wild type, Brain, medicine.disease, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Blood-Brain Barrier, Neurology (clinical)
Abstract

Mucopolysaccharidosis type IIIA (MPS IIIA, Sanfilippo A) is a neurodegenerative lysosomal storage disorder caused by the deficiency of sulphamidase enzyme (SGSH) leading to accumulation of heparan sulfate (HS). We quantitatively and structurally characterize primary stored HS and other glycosaminoglycans (GAGs) possibly accumulated through a secondary storage in brain, liver, kidney and lung of MPS IIIA mouse model. This analysis was also performed in MPS IIIA mice upon the intravenous treatment with an engineered human sulphamidase (chimeric hSGSH) capable to increase its secretion from the liver and to cross the blood-brain barrier. MPS IIIA animals showed a huge accumulation of HS, from ~15 up to ~24-times higher than wild type and also of hyaluronic acid (HA) (from 2.5 up to ~5.0-times more) and chondroitin sulfate (CS)/dermatan sulfate (DS) (from ~2 up to ~5-times more) in all studied organs. We also observed a significant increase in the overall HS charge density and in particular of 2-O-sulfation in MPS IIIA mice organs. 8 months after a systemic treatment with an engineered SGSH, the enzyme was highly efficient in the reduction of all accumulated GAGs in liver, brain and lung up to values of wild type mice. On the contrary, even if reduced, GAGs levels still remained significantly elevated in kidney. Overall data obtained by this detailed analysis of GAGs in the different organs of affected and treated animals with chimeric hSGSH may have implications for the evaluation of an effective therapeutic option of MPS IIIA and for the reduction of related neuropathology.

Published
2016
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8. dHPLC efficiency for semi-automated cDNA-AFLP analyses and fragment collection in the apple scab-resistance gene model

Author

Vilma Mantovani, Luca Dondini, D. Bastia, Valeria Rizzi, Pietro Piffanelli, Valentina Gualdi, Stefano Tartarini, Graziano Zannini, Elena Marasco, Roberta Paris, Paris R., Dondini L., Zannini G., Bastia D., Marasco E., Gualdi V., Rizzi V., Piffanelli P., Mantovani V., and Tartarini S.

Subjects
DNA, Complementary, Gene model, Plant Science, Genes, Plant, Plant–pathogen interaction, Denaturing high performance liquid chromatography, chemistry.chemical_compound, Ascomycota, Fragment (logic), Gene Expression Regulation, Plant, Defense, Genetics, Gene ontology annotation, Amplified Fragment Length Polymorphism Analysis, Gene, Malus x domestica, Chromatography, High Pressure Liquid, Disease Resistance, Plant Diseases, Gel electrophoresis, Chromatography, biology, Cdna aflp, Gene Expression Profiling, food and beverages, qRT-PCR, biology.organism_classification, chemistry, Apple scab, Malus, Host-Pathogen Interactions, DNA
Abstract

cDNA-AFLP analysis for transcript profiling has been successfully applied to study many plant biological systems, particularly plant-microbe interactions. However, the separation of cDNA-AFLP fragments by gel electrophoresis is reported to be labor-intensive with only limited potential for automation, and the collection of differential bands for gene identification is even more cumbersome. In this work, we present the use of dHPLC (denaturing high performance liquid chromatography) and automated DNA fragment collection using the WAVE(®) System to analyze and recover cDNA-AFLP fragments. The method is successfully applied to the Malus-Venturia inaequalis interaction, making it possible to collect 66 different transcript-derived fragments for apple genes putatively involved in the defense response activated by the HcrVf2 resistance gene. The results, validated by real time quantitative RT-PCR, were consistent with the plant-pathogen interaction under investigation and this further supports the suitability of dHPLC for cDNA-AFLP transcript profiling. Features and advantages of this new approach are discussed, evincing that it is an almost fully automatable and cost-effective solution for processing large numbers of samples and collecting differential genes involved in other biological processes and non-model plants.

Published
2012
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