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Plasma waves generated in the wake of intense, relativistic laser1,2 or particle beams3,4 can accelerate electron bunches to gigaelectronvolt energies in centimetre-scale distances. This allows the realization of compact accelerators with emerging applications ranging from modern light sources such as the free-electron laser to energy frontier lepton colliders. In a plasma wakefield accelerator, such multi-gigavolt-per-metre wakefields can accelerate witness electron bunches that are either externally injected5,6 or captured from the background plasma7,8. Here we demonstrate optically triggered injection9–11 and acceleration of electron bunches, generated in a multi-component hydrogen and helium plasma employing a spatially aligned and synchronized laser pulse. This ‘plasma photocathode’ decouples injection from wake excitation by liberating tunnel-ionized helium electrons directly inside the plasma cavity, where these cold electrons are then rapidly boosted to relativistic velocities. The injection regime can be accessed via optical11 density down-ramp injection12–16 and is an important step towards the generation of electron beams with unprecedented low transverse emittance, high current and 6D-brightness17. This experimental path opens numerous prospects for transformative plasma wakefield accelerator applications based on ultrahigh-brightness beams. Electron bunches are generated and accelerated to relativistic velocities by tunnel ionization of neutral gas species in a plasma. This represents a step towards ultra-bright, high-emittance beams in plasma wakefield accelerators. [This summary has been amended from ‘laser-plasma’ to ‘plasma wakefield’ accelerators.]

To develop plasma wakefield acceleration into a compact and affordable replacement for conventional accelerators, beams of charged particles must be accelerated at high efficiency in a high electric field; here this is demonstrated for a bunch of charged electrons ‘surfing’ on a previously excited plasma wave. Particle colliders that operate at the high-energy frontier using electric fields generated by radio waves are approaching the limits of feasibility in terms of size and cost, but there are other acceleration techniques that could make less expensive and more compact devices. The plasma wakefield accelerator, in which an electron bunch is accelerated by making it 'surf' on a plasma wave excited by another electron bunch, promises an energy gain in the gigaelectron-volt regime over just a few centimetres — an energy gain that requires hundreds of metres using traditional accelerators. Previously, this technique had only been used to accelerate a very small number of electrons at a time. Now, researchers working at FACET, the Facility for Advanced Accelerator Experimental Tests at SLAC National Accelerator Laboratory, USA, have achieved acceleration of about half a billion electrons at once with an unprecedented efficiency for a plasma accelerator. This achievement could be a milestone in the development of affordable and compact accelerators for applications ranging from high energy physics to medical and industrial applications. High-efficiency acceleration of charged particle beams at high gradients of energy gain per unit length is necessary to achieve an affordable and compact high-energy collider. The plasma wakefield accelerator is one concept1,2,3 being developed for this purpose. In plasma wakefield acceleration, a charge-density wake with high accelerating fields is driven by the passage of an ultra-relativistic bunch of charged particles (the drive bunch) through a plasma4,5,6. If a second bunch of relativistic electrons (the trailing bunch) with sufficient charge follows in the wake of the drive bunch at an appropriate distance, it can be efficiently accelerated to high energy. Previous experiments using just a single 42-gigaelectronvolt drive bunch have accelerated electrons with a continuous energy spectrum and a maximum energy of up to 85 gigaelectronvolts from the tail of the same bunch in less than a metre of plasma7. However, the total charge of these accelerated electrons was insufficient to extract a substantial amount of energy from the wake. Here we report high-efficiency acceleration of a discrete trailing bunch of electrons that contains sufficient charge to extract a substantial amount of energy from the high-gradient, nonlinear plasma wakefield accelerator. Specifically, we show the acceleration of about 74 picocoulombs of charge contained in the core of the trailing bunch in an accelerating gradient of about 4.4 gigavolts per metre. These core particles gain about 1.6 gigaelectronvolts of energy per particle, with a final energy spread as low as 0.7 per cent (2.0 per cent on average), and an energy-transfer efficiency from the wake to the bunch that can exceed 30 per cent (17.7 per cent on average). This acceleration of a distinct bunch of electrons containing a substantial charge and having a small energy spread with both a high accelerating gradient and a high energy-transfer efficiency represents a milestone in the development of plasma wakefield acceleration into a compact and affordable accelerator technology.

Plasma accelerators driven by particle beams are a very promising future accelerator technology as they can sustain high accelerating fields over long distances with high energy efficiency. They rely on the excitation of a plasma wave in the wake of a drive beam. To generate the plasma, a neutral gas can be field-ionized by the head of the drive beam, in which case the distance of acceleration and energy gain can be strongly limited by head erosion. Here we overcome this limit and demonstrate that electrons in the tail of a drive beam can be accelerated by up to 27 GeV in a high-ionization-potential gas (argon), boosting their initial 20.35 GeV energy by 130%. Particle-in-cell simulations show that the argon plasma is sustaining very high electric fields, of ∼150 GV m−1, over ∼20 cm. The results open new possibilities for the design of particle beam drivers and plasma sources., Plasma accelerators driven by particle beams are a promising technology, but the acceleration distance and energy gain are strongly limited by head erosion in a high-ionization-potential gas. Here the authors observe up to 130% energy boost in a self-focused electron beam, with limited head erosion.

Die medikamentose Nierensteinauflosung hat in letzter Zeit wieder an Interesse gewonnen. Im vorliegenden Versuch sollten zunachst verschiedene heute gebrauchliche Losungsmittel an Steinen gleicher chemischer Zusammensetzung gepruft und miteinander verglichen werden. Die chemische Analyse der Steine vor und nach Bespulung in vitro sollte einen Einblick in die Frage geben, ob das Verhaltnis der einzelnen chemischen Komponenten zueinander fur den Grad des Spuleffektes von ausschlaggebender Bedeutung ist und ob dabei bestimmte Gesetzmasigkeiten vorliegen. Weiterhin interessierte die Frage, welche Steinbestandteile von den einzelnen Losungsmitteln vorzugsweise angegriffen werden.