1. Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients
- Author
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Nils Jimmy Hidalgo, Elizabeth Pando, Rodrigo Mata, Nair Fernandes, Sara Villasante, Marta Barros, Daniel Herms, Laia Blanco, Joaquim Balsells, Ramon Charco, Institut Català de la Salut, [Hidalgo NJ, Pando E] Universitat Autònoma de Barcelona, Bellaterra, Spain. Servei de Cirurgia Hepatobiliopancreàtica i Trasplantaments, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Mata R, Fernandes N, Villasante S, Barros M, Herms D, Blanco L, Balsells J, Charco R] Servei de Cirurgia Hepatobiliopancreàtica i Trasplantaments, Vall d’Hebron Hospital Universitari, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus
- Subjects
enfermedades del sistema digestivo::enfermedades pancreáticas::pancreatitis [ENFERMEDADES] ,Pancreatitis - Mortalitat ,Otros calificadores::Otros calificadores::Otros calificadores::/mortalidad [Otros calificadores] ,Comorbiditat ,epidemiología y bioestadística::epidemiología::proceso salud-enfermedad::comorbilidad [SALUD PÚBLICA] ,Digestive System Diseases::Pancreatic Diseases::Pancreatitis [DISEASES] ,Other subheadings::Other subheadings::Other subheadings::/mortality [Other subheadings] ,Gastroenterology ,General Medicine ,Epidemiology and Biostatistics::Epidemiology::Health-Disease Process::Comorbidity [PUBLIC HEALTH] - Abstract
Acute pancreatitis; Comorbidity; Hospital mortality Pancreatitis aguda; Comorbilidad; Mortalidad hospitalaria Pancreatitis aguda; Comorbilitat; Mortalitat hospitalària Background The impact of pre-existing comorbidities on acute pancreatitis (AP) mortality is not clearly defined. Our study aims to determine the trend in AP hospital mortality and the role of comorbidities as a predictor of hospital mortality. Methods We analyzed patients aged ≥ 18 years hospitalized with AP diagnosis between 2016 and 2019. The data have been extracted from the Spanish National Hospital Discharge Database of the Spanish Ministry of Health. We performed a univariate and multivariable analysis of the association of age, sex, and comorbidities with hospital mortality in patients with AP. The role of the Charlson and Elixhauser comorbidity indices as predictors of mortality was evaluated. Results A total of 110,021 patients diagnosed with AP were hospitalized during the analyzed period. Hospital mortality was 3.8%, with a progressive decrease observed in the years evaluated. In multivariable analysis, age ≥ 65 years (OR: 4.11, p 1.5 (OR: 2.03, p 1.5 (OR: 2.71, p
- Published
- 2023
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