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9 results on '"Nobuhiro Sakaki"'

1. Endoscopic three-categorical diagnosis of Helicobacter pylori infection using linked color imaging and deep learning: a single-center prospective study (with video)

Author

Hiroshi Kawahira, Hiroshi Kawachi, Hirotaka Nakashima, and Nobuhiro Sakaki

Subjects
Male, Cancer Research, medicine.medical_specialty, Color, Single Center, Sensitivity and Specificity, Helicobacter Infections, 03 medical and health sciences, Deep Learning, 0302 clinical medicine, Predictive Value of Tests, Surgical oncology, Internal medicine, medicine, Humans, Diagnosis, Computer-Assisted, Endoscopy, Digestive System, Prospective Studies, Medical diagnosis, Prospective cohort study, Aged, Helicobacter pylori, biology, business.industry, Incidence (epidemiology), Gastroenterology, Cancer, Intestinal metaplasia, General Medicine, Middle Aged, Image Enhancement, biology.organism_classification, medicine.disease, Oncology, Gastric Mucosa, Area Under Curve, 030220 oncology & carcinogenesis, Feasibility Studies, Female, 030211 gastroenterology & hepatology, Atrophy, business
Abstract

Helicobacter pylori (H. pylori) eradication is required to reduce incidence related to gastric cancer. Recently, it was found that even after the successful eradication of H. pylori, an increased, i.e., moderate, risk of gastric cancer persists in patients with advanced mucosal atrophy and/or intestinal metaplasia. This study aimed to develop a computer-aided diagnosis (CAD) system to classify the status of H. pylori infection of patients into three categories: uninfected (with no history of H. pylori infection), currently infected, and post-eradication. The CAD system was based on linked color imaging (LCI) combined with deep learning (DL). First, a validation dataset was formed for the CAD systems by recording endoscopic movies of 120 subjects. Next, a training dataset of 395 subjects was prepared to enable DL. All endoscopic examinations were recorded using both LCI and white-light imaging (WLI). These endoscopic data were used to develop two different CAD systems, one for LCI (LCI-CAD) and one for WLI (WLI-CAD) images. The diagnostic accuracy of the LCI-CAD system was 84.2% for uninfected, 82.5% for currently infected, and 79.2% for post-eradication status. Comparisons revealed superior accuracy of diagnoses based on LCI-CAD data relative based on WLI-CAD for uninfected, currently infected, and post-eradication cases. Furthermore, the LCI-CAD system demonstrated comparable diagnostic accuracy to that of experienced endoscopists with the validation data set of LCI. The results of this study suggest the feasibility of an innovative gastric cancer screening program to determine cancer risk in individual subjects based on LCI-CAD.

Published
2020

2. Peptic ulcer recurrence during maintenance therapy with H 2 -receptor antagonist following first-line therapy with proton pump inhibitor

Author

Eizo Kaneko, Shigeru Asaki, Saburo Nakazawa, Yoshio Hoshihara, Takashi Nakamura, Shigeru Harasawa, Nobuhiro Sakaki, Goro Kajiyama, Kiyoshi Ashida, Nobuya Ogawa, Kenzo Kobayashi, Tadayoshi Takemoto, Masahiro Asaka, Yasutoshi Muto, and Tsuneyoshi Yao

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, medicine.drug_class, Lansoprazole, Proton-pump inhibitor, Gastroenterology, 2-Pyridinylmethylsulfinylbenzimidazoles, Maintenance therapy, Histamine H2 receptor, Recurrence, Internal medicine, medicine, Humans, Stomach Ulcer, business.industry, Proton Pump Inhibitors, Middle Aged, Hepatology, Anti-Ulcer Agents, Colorectal surgery, Clinical trial, Histamine H2 Antagonists, Duodenal Ulcer, Female, business, Omeprazole, Abdominal surgery, medicine.drug
Abstract

We investigated the peptic ulcer recurrence rates during maintenance therapy with H2-receptor antagonists (H2RAs) following first-line therapy with a proton pump inhibitor (PPI). Patients with gastric ulcer (GU) or duodenal ulcer (DU) were enrolled in this study; 583 eligible patients (GU, 325; DU, 258) were administered lansoprazole (30 mg/day for 8 weeks for GU, and the same dosage for 6 weeks for DU) as first-line therapy, and a half dose of H2RA as maintenance therapy for 12 months. Endoscopic photographs were taken before administration and after 8 (GU) and 6 (DU) weeks of lansoprazole administration. Ulcer stage was evaluated using the classification of Sakita and Miwa. Endoscopic examinations were performed 6 months or 12 months after the start of maintenance therapy or when a recurrence was suspected because of the appearance of subjective symptoms. The healing rates for GU and DU patients after completion of lansoprazole therapy were 79% in both groups, while the S2-stage healing rates were 18% and 31%, respectively. At 1 year after the start of maintenance therapy, the recurrence rates were 25% for GU and 39% for DU patients. In DU patients, the recurrence rates from S1-stage and S2-stage were 49% and 20%, respectively (P = 0.004), but no significant difference was found between these rates in GU patients. The recurrence rates in H. pylori-positive patients before lansoprazole administration were 27% for GU and 43% for DU patients. We concluded that the maintenance therapy with a half-dose of H2RA following PPI therapy was insufficient to prevent recurrences of GU and DU.

Published
2000

3. Relationship between progression of gastric mucosal atrophy andHelicobacter pylori infection: Retrospective long-term endoscopic follow-up study

Author

Chikara Ishikawa, Yoshiya Yamada, Takeo Arakawa, Hiroaki Katou, Nobuhiro Sakaki, Jun-ichi Ishiwata, Kumiko Momma, Yuyang Tu, Naoto Egawa, and Terumi Kamisawa

Subjects
Adult, Male, medicine.medical_specialty, Gastroenterology, Helicobacter Infections, Serology, Atrophy, Internal medicine, Gastroscopy, medicine, Gastric mucosa, Humans, Aged, Retrospective Studies, Helicobacter pylori, biology, business.industry, Retrospective cohort study, Middle Aged, Hepatology, medicine.disease, biology.organism_classification, Antibodies, Bacterial, Colorectal surgery, medicine.anatomical_structure, Gastric Mucosa, Immunoglobulin G, Female, business, Follow-Up Studies, Abdominal surgery
Abstract

A retrospective long-term endoscopic follow-up study was designed to examine atrophic changes in the gastric mucosa over time in Helicobacter pylori-positive patients. Over a period of 8-17 years (mean, 13.4 years) 22 subjects (5 men, 17 women, mean age, 55 years) without localized gastroduodenal lesions underwent serial endoscopic examinations and serological and microbiological assessments of H. pylori infection. The extent of atrophic mucosa in the gastric body was expressed using the Kimura-Takemoto classification of atrophic pattern. Atrophic patterns were unchanged over time in 7 H. pylori-seronegative and culture-negative subjects with normal stomach, and in 1 seropositive and culture-negative subject with severe atrophy. Seven of 10 H. pylori culture-positive subjects not including three with the O-3 pattern, i.e., open type atrophic pattern, exhibited a cephalad shift of atrophic pattern. The cumulative progression rates of atrophy in the culture-positive subjects excluding O-3 subjects, were 10% after 2 years, 20% after 4 years, 50% after 6 years, and 70% after 8 years. The increases in the extent of the atrophic area were discontinuous, in terms of age, in the H. pylori-positive individuals and occasionally advanced rapidly within periods of several years with no relation to age.

Published
1997

4. Abstracts of selected papers presented at the 79th general meeting of the Japanese Society of Gastroenterology March 29–31, 1993, Kyoto, Japan

Author

Akira Uehara, Masayoshi Namiki, Masashi Yoneda, Yvette Taché, Hidekazu Suzuki, Soichiro Miura, Michiro Otaka, Osamu Masamune, Shin Fukudo, Taisuke Nomura, R. Abe, T. Shimosegawa, Keiya Nakamura, Akira Aoike, Hiroya Yamaguchi, Toshinari Kimura, Toshikazu Nakamura, Kunio Matsumoto, Tomoaki Tomiya, Kenji Fujiwara, Kenji Mori, Mitsuru Yasunaga, Hiroshi Yasuda, Itaru Kojima, Hiroo Ohnishi, Masahito Nagaki, Norio Koide, Takao Tsuji, Kouichi Nagano, Sunao Kawano, Ken Kihira, Kiichi Satoh, Nobuhiro Sakaki, Yoshiya Yamada, Mikio Karita, Tateo Yoshimatsu, Takatoshi Nakashima, Nobuo Aoyama, Yoshihiro Fukuda, Kazutami Tamura, T. Sugiyama, T. Yabana, Jaw-Town Lin, Nobuo Sueoka, Katsuhiko Iwakiri, Sumio Watanabe, Nobuhiro Sato, Kazuaki Yamasaki, Kazuichi Okazaki, Hirokazu Nishino, Tadaki Muroi, Yoshiro Matsuda, Mikihiro Tsutsumi, Masahide Oshita, Yoshiyuki Takei, Ryukichi Kumashiro, Kyuichi Tanikawa, Yasuyuki Nagao, Takeshi Okanoue, Nobuhiro Tsukada, Masaya Oda, Motoyasu Ishii, Takeshi Yamamoto, Masafumi Komatsu, Ko Nakajima, Shotaro Sakisaka, Fumio Itoh, Kohzoh Imai, Yutaka Shintani, Tadao Bamba, Eiichi Saito, Akifumi Ogihara, Masaya Sasaki, Kazuma Fujimoto, Ryuichi Iwakiri, Motonobu Hosomi, Fumio Takada, Makoto Obayashi, Atushi Kitano, Sumiko Nagoshi, T. Tanaka, T. Monna, Yutaka Matsuzaki, Hiroyuki Sugimoto, Hideki Machishi, Ryuji Mizumoto, Kazuya Matsuda, Yoshihito Uchida, H. Okano, N. Aoyama, Masahiko Yamada, Michio Hongo, Yoshihisa Shibata, Masahiko Miyachi, Yuji Nimura, Toshiaki Neya, Masatoshi Mizutani, Jun Inoue, Masahiko Nakamura, Sachiko Futami, K. Funakoshi, K. Sugimura, Yasushi Iwao, Toshifumi Hibi, Kazuo Kusugami, Kimitomo Morise, Mitsuo Kimura, Nobuo Hiwatashi, Shinichiro Kanzaki, Kazuya Makiyama, Makoto Yamamura, Masamichi Satomi, Hirofumi Harada, Hiroshi Shimada, Norimasa Yoshida, Toshikazu Yoshikawa, Hideyuki Hiraishi, Takashi Harada, Masayuki Suzuki, E. Masuda, S. Kawano, H. Matsui, H. Fukutomi, Nobuhide Oshitani, Atsuo Kitano, Makoto Suematsu, Hitoshi Togashi, Haruhide Shinzawa, Hiroya Murakami, Hiroshi Takagi, Hiroshi Kasugai, Masaharu Tatsuta, Takeshi Urabe, Masashi Unoura, Naoki Yamanaka, Eizo Okamoto, Tadatoshi Takayama, Susumu Yamasaki, Kazuhiko Kita, Masaaki Ebara, Yasuo Majima, Osamu Matsui, Hiroshi Demachi, Toshihito Seki, Kyoichi Inoue, Kunihiko Ohnishi, Susumu Ito, Akira Kaneko, Norio Hayashi, Keiichiro Yoneyama, Keiji Mitamura, Katsuyoshi Higashi, Makoto Hoshino, Hisataka Ogasawara, Keigo Sirahama, Naoki Hashimoto, Haruki Yamada, Yasushi Shiratori, Ken’ichi Okano, Masami Minemura, Akiharu Watanabe, Tsutomu Masaki, Masaaki Tokuda, Tatsuyuki Kawano, Mitsuo Endo, Teruo Kouzu, Humiaki Sakaguchi, Nobuyoshi Hanyu, Teruaki Aoki, Chikao Shimamoto, Ichiro Hirata, Koji Sasajima, Kaiyo Takubo, Yukimitsu Kawaura, Kazuyuki Kawakami, Hiroto Hayashi, Takashi Suzuki, Kazuo Watanabe, Hidenobu Watanabe, Naoki Hino, Toshihiro Higashi, Tomohiro Shiro, Yasushi Hongo, Hideki Tada, K. Saitoh, Y. Akiyama, Shoji Mitsufuji, Yasunari Tsuchihashi, K. Nishimura, Y. Hosokawa, Ryo Wada, Kouichi Suda, Ken-ichi Mafune, Yasuo Idezuki, Motowo Mizuno, Mamoru Watanabe, Takayuki Matsumoto, Kenzo Kobayashi, Takeo Yamaguchi, T. Watanabe, Y. Kubota, Akira Andoh, Yoshihide Fujiyama, Kanji Tanaka, Koshirou Hioki, Yuji Hinoda, and Haruo Ohtani

Subjects
medicine.medical_specialty, business.industry, Gastroenterology, Hepatology, medicine.disease, Ulcerative colitis, Colorectal surgery, Fulminant hepatic failure, Surgical oncology, Internal medicine, medicine, Acute pancreatitis, Pancreatitis, business, Abdominal surgery
Published
1993

5. Abstracts Of Selected Papers Presented at the 32nd Annual Meeting of the Japanese Society of Gastroenterology

Author

Eiji Kanehira, Junichi Yamao, Yasumasa Niwa, Takesada Mori, Masao Omata, Shigeaki Ishizaka, Takushi Monden, Yuji Naito, Ryukichi Kumashiro, Noritoshi Tanida, K. Fujisawa, Yoshiaki Inui, Yuji Tanaka, Keiji Kitagami, Takayoshi Tobe, Hisanori Uchida, Masaki Fujimura, Akira Terano, Kazue Ozawa, Kumiko Monma, Kenji Sakakibara, Yuji Mizokami, Tetsuo Arakawa, Hiroshi Obata, Sumio Kawata, Hajime Ohishi, Kazumasa Miki, Tadashi Koike, Hideyuki Kanoh, Yoshikazu Yamaguchi, Hitoshi Kato, Sumio Takayama, Hirohumi Masumoto, Masao Saito, Yasuhiro Kawai, Osamu Masamune, Nobuyuki Kobayashi, Masahi Nobunaga, Teruaki Aoki, Yukihiro Tsuchiya, Masayuki Tsujisaki, Mogi Yoshioro, Kohzoh Imai, Toshihiko Namihisa, Shozo Saito, Mikihiko Ueno, Toshiyuki Kato, Nobuo Akiyama, Hisayuki Sugimoto, M. Tanaka, Tetuo Yamamoto, Makoto Kimoto, Morito Monden, Kuichi Tanikawa, Masayoshi Yamauchi, Nobuhiro Sakaki, Okajima, Atsushi Maeda, Takeshi Nagao, Akira Yanagawa, Terunobu Saito, Hiroyuki Sakuma, Toshikazu Yoshikawa, Takashi Kato, Yoshihisa Tsukamoto, Michiro Otaka, Kyuichi Tanikawa, Masao Ichinose, Kenzo Kobayashi, Sagawa H, Satoru Todo, Kazuei Ogoshi, Haruo Kameda, Kazuo Shiraki, Takafumi Ichida, Masabumi Hihara, Sumio Sakamaki, Shinichi Ota, Shinichi Ogura, Yoshinori Nio, Takaomi Hamada, Susumu Tazuma, Kazuhide Higuchi, Masanobu Yoshimoto, Yukimitsu Kawaura, Hiromi Nishiarai, Toru Endo, Yasutoshi Muto, Masahiro Asaka, Izumi Yokoyama, and K. Tanikawa

Subjects
medicine.medical_specialty, business.industry, Surgical oncology, Internal medicine, General surgery, Gastroenterology, Medicine, Hepatology, business, Colorectal surgery, Abdominal surgery
Published
1992

6. Abstracts Of Selected Papers Presented At The 75Th General Meeting Of The Japanese Society Of Gastroenterology March 27–29, 1989 — Yokohama, Japan

Author

Satoshi Tanabe, Katsunori Saigenji, Shigeru Asaki, Akira Sato, Isao Takeda, Satoshi Nakano, Yoshihiro Inoue, Atsushi Kano, Yasubumi Shiina, Takeshi Miwa, Hiroshi Takahashi, Kimio Namatame, C. Sugawa, R. Nakamura, Hideichi Uchida, Tadashi Kodama, Shinji Oka, Yukinori Okazaki, Nobuhiro Sato, Tatsuo Ogihara, Yasumasa Niwa, Saburo Nakazawa, Yoshiteru Azuumi, Yutaka Saito, Kunio Sato, Ariyoshi Iwasaki, Masanao Abe, Mamoru Miyairi, Kyoichiro Suyama, Tetsuo Hayakawa, Toshiyuki Suzuki, Hirofumi Miyake, Koji Ochi, Hideyuki Wakasugi, Akihiro Funakoshi, Keiichi Sugiyama, Tadao Manabe, Nobuo Baba, Masahiro Yamamoto, Yoichi Saitoh, Kazutami Tamura, Yoshihiro Fukuda, Nobuhiro Sakaki, Katsuyuki Ietomi, Masahiro Yamada, Toshifumi Ohkusa, Shinichi Takahashi, Shozo Saito, Kiichi Satoh, Ken Kimura, Shigeji Ito, Yoshihiro Kohli, S. Koyama, T. Bamba, A. Takagi, K. Kojima, T. Sugiyama, T. Yabana, Masahiro Tada, Masaki Shigeeda, M. Yoshida, I. Imoto, Takafumi Hashiguchi, Tadashi Shibue, Hiroshi Saita, Motonobu Murakami, Masahiko Tsujii, Sunao Kawano, Takayuki Shirai, Shigeru Harasawa, Tomikazu Yamamoto, Akiyoshi Nishio, Susumu Saeki, Toumei Oh, Masaharu Tatsuta, Hiroyasu Ishii, Hideki Nishiwaki, Katsusuke Satake, Yasushi Matsuzaki, Naomi Tanaka, Akira Knakano, Tsuneo Fukushima, I. Horiuchi, G. Kajiyama, Hideaki Saito, Yasuhiko Morioka, Soichiro Miura, Masahiro Yoshioka, and Naomi Takahashi

Subjects
Gastroenterology
Published
1991

7. Abstracts of selected papers presented at the 30th Annual meeting of the Japanese Society of Gastroenterology

Author

Kazuya Makiyama, Tadahiko Fuchigami, Nobuhiro Sakaki, Naofumi Osaka, H Fujishima, Junji Yoshino, Kazuaki Nakashio, A. Obata, Masaharu Tatsuta, Masahiko Takamasu, Mitsuo Iida, Yukinori Okazaki, Akimichi Chonan, Masaaki Matsukawa, Hiroyasu Makuuchi, Mitsuo Okada, Akiyoshi Yamada, Hiroto Nishimata, Goro Yamaki, Yoshito Nishimata, Mitushiro Kida, and Kensaburo Imamura

Subjects
medicine.medical_specialty, Surgical oncology, business.industry, General surgery, Internal medicine, Gastroenterology, medicine, Hepatology, business, Colorectal surgery, Abdominal surgery
Published
1990

8. Proceedings of the 19th autumn meeting from October 18 to 20, 1977-Nara, Japan

Author

T. Matsumura, Hikoo Shirakabe, Moriya Yamashiro, Tokio Ono, Hikaru Watanabe, Nobuhiro Sakaki, Nobuo Hiwatashi, Keiichi Kawai, Hiroo Furukawa, Noritsugi Ikeda, Haruki Wakasa, Tsuyoshi Suzaki, Tetsuichiro Muto, Masami Oishi, Yoshimasa Suto, Isamu Kino, Kenzo Kobayashi, Hiroshi Takemura, Shigeru Suzuki, Mamoru Nishizawa, Shuji Tsuchiya, Susumu Morikawa, Takeo Miyake, Shigeo Kobayashi, Atsuo Kitano, Yukinori Okazaki, Tadashi Yamazaki, Yasutake Yamamoto, Tsuyoshi Tajima, Yoshiaki Maeda, Michio Tanaka, Kyoichi Nakamura, and Masahiro Tada

Subjects
medicine.medical_specialty, business.industry, Surgical oncology, Internal medicine, General surgery, Gastroenterology, Medicine, Hepatology, business, Colorectal surgery, Abdominal surgery
Published
1978

9. Proceedings of the 25th annual meeting From October 13–15, 1983—Yamaguchi, Japan

Author

Sachio Takasu, Thouichiro Takizawa, Morio Koike, Masaharu Tatsuta, Shigeru Okuda, Junichi Okuda, Kazunori Ida, Naoyuki Yamada, Sohtaroh Furuchi, Kimie Kurokawa, Hitomi Adachi, Nobuhiro Sakaki, Masahiro Tada, Akira Yachi, Kimio Namatame, Hiromu Watanabe, Shuichi Ohara, Shigeru Asaki, Junji Yoshino, Saburo Nakazawa, Toshihiro Hasegawa, Shigeru Suzuki, Akira Nakahara, Hisayuki Fukutomi, Katsunori Yoshimura, Toshihiko Saito, Kazumichi Harada, Hideki Hayashi, Mitsuru Sasako, Masaru Iwasaki, Osamu Kato, Kazuhiko Hattori, Shigemi Ariyama, Yoshito Ohshita, Seishiro Mimura, Makoto Ichii, Masatoshi Esaki, Hideo Hiratsuka, Tsuyoshi Nishisaka, Motoki Yonekawa, Kenichi Ido, Ken Kimura, Yoshiaki Ito, Tatsuzo Kasugai, Masahiro Maruyama, Teruo Kouzu, Toshio Hirashima, Yanao Oguro, Masayuki Ozaki, Wataru Imaoka, Toshio Nishioka, Toshikazu Sekiguchi, Akihiro Funakoshi, Hiroshi Ibayashi, S. Naruse, D. F. Magee, Makoto Otsuki, Atsushi Ohki, Mitsuyoshi Namba, Tatsuo Matsuyama, Shinya Kishimoto, Mikio Imamura, Toshio Sato, S. Nakaya, Y. Saitoh, Tomio Kanno, Tetsuya Marino, Toshikuni Okada, Takahiro Fujimori, Kou Nagasako, Masahito Ohida, Katsunori Saigenji, Kazuo Hayakawa, Sotaro Fukuchi, Shigeru Asakh, Daisuke Shibuya, Toru Yambe, Satoru Shibuk, Toshiki Okata, Koichi Yoshida, Tadayoshi Shoji, Shoichiro Itch, Fukuharu Mochizuki, Tsutomu Hamada, Tadashi Yarita, Yasumasa Baba, Takeo Takekoshi, Toshiaki Misono, H. Nakano, K. Sasaki, Atsunobu Misumi, Masanobu Akagi, Hajime Yamaguchi, Shigeaki Yoshida, Hiroshi Kozawa, Shinpei Kawaguchi, Hiroyasu Iishi, Keishi Takechi, Hidehiro Nomura, Mitsumasa Nishi, Akihiro Yamaguchi, Kitao Hachisuka, Kazuhiro Sakamoto, Katsutaka Mori, Tsutomu Sekoguchi, Ryuji Mizumoto, Yoshinobu Higashino, Takukazu Nagakawa, Seiki Matsuno, Toshihide Imaizumi, Fujio Hanyu, Masayuki Sada, Toshimichi Nakayama, Hisao Tajiri, Masayoshi Yoshimori, Kenji Katagiri, Katsuji Hayashi, Keisuke Hamasaki, Hisashi Mimura, Susumu Miyata, Tadashi Shibue, Seikoh Shimaguchi, Joe Ariyama, Kazuo Harima, Fumio Asagami, Masafumi Ichikawa, and Yasuo Naito

Subjects
medicine.medical_specialty, Gefarnate, Surgical oncology, business.industry, General surgery, Internal medicine, Gastroenterology, medicine, Hepatology, Fulminant hepatitis, business, Colorectal surgery, Abdominal surgery
Published
1984

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