1. Pulmonary infiltrates in patients with haematologic malignancies: transbronchial lung biopsy increases the diagnostic yield with respect to neoplastic infiltrates and toxic pneumonitis
- Author
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A. Mulabecirovic, Holger W. Auner, Heinz Sill, H. Popper, Robert Krause, P. Gaulhofer, and C. Hesse
- Subjects
Adult ,Lung Diseases ,Male ,medicine.medical_specialty ,Pathology ,Biopsy ,Antineoplastic Agents ,Hemorrhage ,Platelet Transfusion ,Bronchoscopies ,Cohort Studies ,Leukemic Infiltration ,Predictive Value of Tests ,Internal medicine ,Bronchoscopy ,medicine ,Fiber Optic Technology ,Humans ,Lung ,Aged ,Retrospective Studies ,Hematology ,medicine.diagnostic_test ,business.industry ,Transbronchial lung biopsy ,Pneumonia ,General Medicine ,Middle Aged ,respiratory system ,medicine.disease ,respiratory tract diseases ,Bronchoalveolar lavage ,Pneumothorax ,Hematologic Neoplasms ,Myelodysplastic Syndromes ,Disease Progression ,Etiology ,Female ,Pulmonary infiltrates ,business ,Bronchoalveolar Lavage Fluid ,Infiltration (medical) - Abstract
We retrospectively evaluated 107 fiberoptic bronchoscopies with and without transbronchial lung biopsy (TBLB) in 98 consecutive patients with haematologic malignancies and pulmonary infiltrates. Bronchoalveolar lavage (BAL) was performed in 45 and BAL plus TBLB in 62 procedures. There was no procedure-related severe haemorrhage, pneumothorax or death. Infectious aetiology was identified in 26 of 107 (24%), toxic pneumonitis in 17 of 107 (16%) and neoplastic infiltration in 9 of 107 (8.5%) episodes. Combined BAL and TBLB was significantly superior to BAL alone with respect to the diagnosis of neoplastic infiltrates (p=0.008) and toxic pneumonitis (p
- Published
- 2004
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