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Your search keyword '"Qiong-Ming Xu"' showing total 2 results
Start Over Author "Qiong-Ming Xu" Publisher springer science and business media llc
2 results on '"Qiong-Ming Xu"'

1. Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation

Author

Zheng-Xia, Zha, Yu, Lin, Ke-Xin, Wang, Yan-Lin, Zhang, Dan, Li, Guo-Qiang, Xu, Qiong-Ming, Xu, and Yan-Li, Liu

Subjects
Pharmacology, Pharmacology (medical), General Medicine
Abstract

Hederacoside C (HSC) has attracted much attention as a novel modulator of inflammation, but its anti-inflammatory mechanism remains elusive. In the present study, we investigated how HSC attenuated intestinal inflammation in vivo and in vitro. HSC injection significantly alleviated TNBS-induced colitis by inhibiting pro-inflammatory cytokine production and colonic epithelial cell apoptosis, and partially restored colonic epithelial cell proliferation. The therapeutic effect of HSC injection was comparable to that of oral administration of mesalazine (200 mg·kg

Published
2022
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