1. Psychological outcomes and surgical decisions after genetic testing in women newly diagnosed with breast cancer with and without a family history
- Author
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Katherine L. Tucker, Judy Kirk, Kristine Barlow-Stewart, Veronica F. Quinn, Marion Harris, Kaaren J. Watts, Christobel Saunders, Llew Mills, Gillian Mitchell, Rachel Susman, Michael Field, Bettina Meiser, Margaret Gleeson, Belinda Rahman, Yoland Antill, Michael T. Bowen, Elizabeth Geelhoed, and Michelle Peate
- Subjects
Adult ,0301 basic medicine ,Heterozygote ,medicine.medical_specialty ,Decision Making ,MEDLINE ,Breast Neoplasms ,Article ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Genetics ,Humans ,Medicine ,Genetic Testing ,Family history ,Medical History Taking ,Genetics (clinical) ,Genetic testing ,BRCA2 Protein ,Ovarian Neoplasms ,medicine.diagnostic_test ,BRCA1 Protein ,business.industry ,Obstetrics ,Regret ,Middle Aged ,medicine.disease ,Distress ,Treatment Outcome ,030104 developmental biology ,030220 oncology & carcinogenesis ,Mutation ,Anxiety ,Female ,Self Report ,medicine.symptom ,business ,Patient education - Abstract
In patients with early breast cancer, personal and tumour characteristics other than family history are increasingly used to prompt genetic testing to guide women’s cancer management (treatment-focused genetic testing, ‘TFGT’). Women without a known strong family history of breast and/or ovarian may be more vulnerable to psychological sequelae arising from TFGT. We compared the impact of TFGT in women with (FH+) and without (FH−) a strong family history on psychological adjustment and surgical decisions. Women aged
- Published
- 2018
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