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Cell damage, one of critical issues in the bioreactor design for animal cell culture, is caused mainly from the bubble bursting at the free surface subjected to strong extensional flows. In this work, extensive computational studies are performed to investigate bubble bursting process in great details. Extensive numerical simulations are performed for a wide range of bubble diameters (from 0.5 to 6 mm) and the surface tension values (from 0.03 to 0.072 N/m), with which effects of the bubble size and surfactant (PF68) concentration on the hydrodynamic stress are investigated. For all the cases, the maximum extensional stress appears at the instance when receding films impact each other at the bottom of the bubble. A model equation based on numerical simulations is presented to predict the maximum extensional stress as a function of the bubble diameter and the surface tension. The bubble diameter has turned out to contribute significantly the maximum hydrodynamic extensional stress. In addition, the bubble collapsed time and the affected volume around a bubble subjected to the critical extensional stress are investigated. The extensional stress estimation is reported as a function of the bubble size and the surface tension. The influence of the bubble size on the maximum stress dominates and extensional stress reaches up to the order of 104 Pa for bubble size of 0.5 mm.

Contamination in a cleanroom may appear even more complicated by the effect of complicated manufacturing processes and indoor equipment. For this reason, detailed information about the concentration of pollutant particles in the cleanroom is needed to control the level of contamination financially and efficiently without any problem in manufacturing process. Allocation method has been developed as one of main ideas to fulfill a function of controlling contamination under the situation. By using this method, weighting factor can be predicted based on cleanliness on sampling spots and the values based on numerical analysis. In this point, the weighting factor indicates how each of contaminant sources influences the concentration of pollutant in the cleanroom. In this paper, when applied allocation method, we propose zoning method to accelerate the calculation time. And it was applied to cleanliness the actual improvement of the turbulent type clean room. As a result, we could estimate quantitatively the amount of contamination generated from the pollution sources. And was proved by experiments that it is possible to improve the level of cleanliness of the cleanrooms by using these results.

During drilling, the precipitation velocity of cuttings within an annulus depends on the density, configuration, and size of the cuttings, and on the density, viscosity, and rheological characteristics of the drilling fluid. In directional drilling in particular, it is difficult to adjust and control the cuttings. In contrast to vertical drilling, it is very important to evaluate the flow characteristics of a drilling flow field. However, research on the transfer features of cuttings is inadequate. In this study, in order to identify transfer features of cuttings, an experiment was performed under wide-ranging conditions by constructing a slim hole annulus (44 mm×30 mm) device. In this experiment, the friction coefficient, pressure loss, particle transport ratio, and particle volume fraction were measured. These quantities were influenced by particle concentration within the flow, pipe rotation, flow volume, and inclination of the annulus. In addition, a mathematical formula for volumetric concentration was deduced and compared to the test results and behavior of cuttings under the other drilling condition was made to be predicted. Therefore, this study can provide meaningful data for vertical and horizontal drilling, and for directional drilling.

We examine the characteristics of helical flow in a concentric annulus with radii ratios of 0.52 and 0.9, whose outer cylinder is stationary and inner cylinder is rotating. Pressure losses and skin friction coefficients are measured for fully developed flows of water and a 0.4% aqueous solution of sodium carboxymethyl cellulose (CMC), when the inner cylinder rotates at the speed of 0∼62.82 rad/s. The transitional flow has been examined by the measurement of pressure losses to reveal the relation between the Reynolds and Rossby numbers and the skin friction coefficients. The effect of rotation on the skin friction coefficient is largely changed in accordance with the axial fluid flow, from laminar to turbulent flow. In all flow regimes, the skin friction coefficient increases due to inner cylinder rotation. The change of skin friction coefficient corresponding to the variation of rotating speed is large for the laminar flow regime, becomes smaller as the Reynolds number increases for the transitional flow regime, and gradually approaches zero for the turbulent flow regime. The value of skin friction coefficient for a radii ratio of 0.52 is about two times larger than for a radii ratio of 0.9. For 0.4% CMC solution, the value of skin friction coefficient for a radii ratio of 0.52 is about four times larger than for a radii ratio of 0.9.

An experimental study was conducted to study solid-liquid mixture upward hydraulic transport of solid particles in vertical and inclined annuli with rotating inner cylinder. Lift forces acting on a fluidized particle play a central role in many important applications, such as the removal of drill cuttings in horizontal drill holes, sand transport in fractured reservoirs and sediment transport, etc. Annular fluid velocities varied from 0.4 m/s to 1.2 m/s. Effect of annulus inclination and drill pipe rotation on the carrying capacity of drilling fluid, particle rising velocity, and pressure drop in the slim hole annulus have been measured for fully developed flows of water and of aqueous solutions of sodium carboxymethyl cellulose (CMC) and bentonite, respectively. For higher particle feed concentration, the hydraulic pressure drop of mixture flow increases due to the friction between the wall and solids or among solids.

An investigation is conducted to understand hydraulic transport characteristics of a solid-liquid mixture flowing vertically upward. Namely, this is the instance that solid particles are carried by non-Newtonian fluids in a slim hole concentric annulus with rotating inner cylinder. In this study a clear acrylic pipe was used in order to observe the movement of solid particles. The bulk axial velocities varied from 0.4 m/s to 1.2 m/s. The mud systems which were utilized included aqueous solution of sodium carboxymethyl cellulose (0.2∼0.4%CMC) and 5% bentonite solutions. Solid volumetric concentration and pressure drops were measured for the various parameters such as inclined annulus, flow rate, and rotational speed of inner cylinder. For both CMC and bentonite solutions, the higher the concentration of the solid particles are, the larger the pressure drops become.

The shape of the polymers in the mixed alkoxide solutions of Si(OC2H5)4 and Zr(n-OC3H7)4 with various water contents (1, 2, 4, and 8 in molar ratio to alkoxide, r) and catalysts was examined by rheological measurements, and its relation with fiber drawing behavior of the solutions was described. It was found that fibers could be drawn in the viscosity range 1–100 P from the acid-catalyzed solutions with lower water contents of the molar ratio H2O/alkoxide, r≤2. On the other hand, no fiber could be drawn from the acid-catalyzed solutions including a large amount of water (r≥4) and the base-catalyzed solutions.