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7 results on '"Seguier, Julie"'

1. Development and validation of a quality of life measurement scale specific to hereditary hemorrhagic telangiectasia: the QoL-HHT

Author

Le, Thi Thao Truc, primary, Martinent, Guillaume, additional, Dupuis-Girod, Sophie, additional, Parrot, Antoine, additional, Contis, Anne, additional, Riviere, Sophie, additional, Chinet, Thierry, additional, Grobost, Vincent, additional, Espitia, Olivier, additional, Dussardier-Gilbert, Brigitte, additional, Alric, Laurent, additional, Armengol, Guillaume, additional, Maillard, Hélène, additional, Leguy-Seguin, Vanessa, additional, Leroy, Sylvie, additional, Rondeau-Lutz, Murielle, additional, Lavigne, Christian, additional, Mohamed, Shirine, additional, Chaussavoine, Laurent, additional, Magro, Pascal, additional, Seguier, Julie, additional, Kerjouan, Mallorie, additional, and Fourdrinoy, Sylvie, additional

Published
2022
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2. Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

Author

Carvelli, Julien, Demaria, Olivier, Vély, Frédéric, Batista, Luciana, Chouaki Benmansour, Nassima, Fares, Joanna, Carpentier, Sabrina, Thibult, Marie-Laure, Morel, Ariane, Remark, Romain, André, Pascale, Represa, Agnès, Piperoglou, Christelle, Assante Miranda, Laura, Baron, William, Belaid, Nourhène, Caillet, Clarisse, Caraguel, Flavien, Carrette, Barbara, Carrette, Florent, Chanuc, Fabien, Courtois, Rachel, Fenis, Aurore, Giordano, Marilyn, Girard-Madoux, Mathilde, Giraudon-Paoli, Marc, Gourdin, Nicolas, Grondin, Gwendoline, Guillot, Franceline, Habif, Guillaume, Jaubert, Solène, Lopez, Julie, Le Van, Mélanie, Lovera, Naouel, Mansuy, Marine, Bonnet, Elodie, Sansaloni, Audrey, Reboul, Annick, Mitry, Emmanuel, Nekkar-Constant, Camille, Péri, Valentine, Ricaut, Paul, Simon, Léa, Vallier, Jean-Baptiste, Vétizou, Marie, Zerbib, Robert, Ugolini, Sophie, Etiennot, Marion, Galluso, Justine, Lyonnet, Luc, Forel, Jean-Marie, Papazian, Laurent, Velly, Lionel, André, Baptiste, Briantais, Antoine, Faucher, Benoit, Jean, Estelle, Seguier, Julie, Veit, Veronique, Harlé, Jean-Robert, Pastorino, Boris, Delteil, Clémence, Daniel, Laurent, Boudsocq, Jean-Paul, Clerc, Axelle, Delmond, Emmanuel, Vidal, Pierre-Olivier, Savini, Hélène, Coutard, Bruno, Cordier, Pierre Yves, Le Dault, Erwan, Guervilly, Christophe, Simeone, Pierre, Gainnier, Marc, Morel, Yannis, Ebbo, Mikael, Schleinitz, Nicolas, and Vivier, Eric

Subjects
0301 basic medicine, Acute Lung Injury, Complement C5a, Inflammation, Complement factor I, Lung injury, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Animals, Humans, Myeloid Cells, Lung, Receptor, Anaphylatoxin C5a, Respiratory Distress Syndrome, CD11b Antigen, Multidisciplinary, medicine.diagnostic_test, SARS-CoV-2, business.industry, COVID-19, respiratory system, Pathophysiology, 3. Good health, Complement system, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Bronchoalveolar lavage, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Immunology, Female, medicine.symptom, Cytokine Release Syndrome, business, Bronchoalveolar Lavage Fluid
Abstract

Coronavirus disease 2019 (COVID-19) is a disease caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has resulted in a pandemic1. The C5a complement factor and its receptor C5aR1 (also known as CD88) have a key role in the initiation and maintenance of several inflammatory responses by recruiting and activating neutrophils and monocytes1. Here we provide a longitudinal analysis of immune responses, including phenotypic analyses of immune cells and assessments of the soluble factors that are present in the blood and bronchoalveolar lavage fluid of patients at various stages of COVID-19 severity, including those who were paucisymptomatic or had pneumonia or acute respiratory distress syndrome. The levels of soluble C5a were increased in proportion to the severity of COVID-19 and high expression levels of C5aR1 receptors were found in blood and pulmonary myeloid cells, which supports a role for the C5a-C5aR1 axis in the pathophysiology of acute respiratory distress syndrome. Anti-C5aR1 therapeutic monoclonal antibodies prevented the C5a-mediated recruitment and activation of human myeloid cells, and inhibited acute lung injury in human C5aR1 knock-in mice. These results suggest that blockade of the C5a-C5aR1 axis could be used to limit the infiltration of myeloid cells in damaged organs and prevent the excessive lung inflammation and endothelialitis that are associated with acute respiratory distress syndrome in patients with COVID-19.

Published
2020
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3. Late-Onset Progressive Multifocal Leukoencephalopathy (PML) and Lymphoma in a 65-Year-Old Patient with XIAP Deficiency

Author

Seguier, Julie, primary, Briantais, Antoine, additional, Ebbo, Mikael, additional, Meunier, Benoit, additional, Aurran, Thérèse, additional, Coze, Stéphanie, additional, Kaphan, Elsa, additional, De Sainte Marie, Benjamin, additional, Sbihi, Zineb, additional, Latour, Sylvain, additional, Cerf-Bensussan, Nadine, additional, Picard, Capucine, additional, Vély, Frédéric, additional, Barlogis, Vincent, additional, and Schleinitz, Nicolas, additional

Published
2021
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4. Acute severe hepatitis in adult-onset Still’s disease: case report and comprehensive review of a life-threatening manifestation

Author

Muller, Romain, primary, Briantais, Antoine, additional, Faucher, Benoit, additional, Borentain, Patrick, additional, Nafati, Cyril, additional, Blasco, Valery, additional, Gregoire, Emilie, additional, Bernit, Emmanuelle, additional, Seguier, Julie, additional, Meunier, Benoit, additional, Harlé, Jean-Robert, additional, Ebbo, Mikael, additional, and Schleinitz, Nicolas, additional

Published
2020
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5. Nailfold videocapillaroscopy alterations in dermatomyositis, antisynthetase syndrome, overlap myositis, and immune-mediated necrotizing myopathy

Author

Soubrier, Caroline, primary, Seguier, Julie, additional, Di Costanzo, Marie-Pierre, additional, Ebbo, Mikael, additional, Bernit, Emmanuelle, additional, Jean, Estelle, additional, Veit, Véronique, additional, Swiader, Laure, additional, Salort-Campana, Emmanuelle, additional, Attarian, Shahram, additional, De Paula, André Maues, additional, Kaplanski, Gilles, additional, Durand, Jean-Marc, additional, Harlé, Jean-Robert, additional, and Schleinitz, Nicolas, additional

Published
2019
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6. Severe Transitory Neonatal Neutropenia Associated with Maternal Autoimmune or Idiopathic Neutropenia

Author

Seguier, Julie, primary, Barlogis, Vincent, additional, Croisille, Laure, additional, Audrain, Marie, additional, Ebbo, Mikael, additional, Beaupain, Blandine, additional, Meunier, Benoit, additional, Vallentin, Blandine, additional, Jean, Rodolphe, additional, Harle, Jean-Robert, additional, Donadieu, Jean, additional, and Schleinitz, Nicolas, additional

Published
2019
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