19 results on '"Sensi, M"'
Search Results
2. EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells
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Rea, K, primary, Sensi, M, additional, Anichini, A, additional, Canevari, S, additional, and Tomassetti, A, additional
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- 2013
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3. Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer
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Alberti, C, primary, Pinciroli, P, additional, Valeri, B, additional, Ferri, R, additional, Ditto, A, additional, Umezawa, K, additional, Sensi, M, additional, Canevari, S, additional, and Tomassetti, A, additional
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- 2011
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- View/download PDF
4. TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells
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Anania, M C, primary, Sensi, M, additional, Radaelli, E, additional, Miranda, C, additional, Vizioli, M G, additional, Pagliardini, S, additional, Favini, E, additional, Cleris, L, additional, Supino, R, additional, Formelli, F, additional, Borrello, M G, additional, Pierotti, M A, additional, and Greco, A, additional
- Published
- 2011
- Full Text
- View/download PDF
5. IGFBP7: an oncosuppressor gene in thyroid carcinogenesis
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Vizioli, M G, primary, Sensi, M, additional, Miranda, C, additional, Cleris, L, additional, Formelli, F, additional, Anania, M C, additional, Pierotti, M A, additional, and Greco, A, additional
- Published
- 2010
- Full Text
- View/download PDF
6. Immunogenicity of advanced glycation end products in diabetic patients and in nephropathic non-diabetic patients on hemodialysis or after renal transplantation
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Buongiorno, A. M., primary, Morelli, S., additional, Sagratella, E., additional, Cipriani, R., additional, Mazzaferro, S., additional, Morano, S., additional, and Sensi, M., additional
- Published
- 2008
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- View/download PDF
7. Mutually exclusive NRASQ61R and BRAFV600E mutations at the single-cell level in the same human melanoma
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Sensi, M, primary, Nicolini, G, additional, Petti, C, additional, Bersani, I, additional, Lozupone, F, additional, Molla, A, additional, Vegetti, C, additional, Nonaka, D, additional, Mortarini, R, additional, Parmiani, G, additional, Fais, S, additional, and Anichini, A, additional
- Published
- 2006
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8. Cerebellar ataxia, hypogonadism and chorioretinopathy: molecular analysis of an Italian family
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Rizzi, R., primary, Carelli, V., additional, Monari, L., additional, Mochi, M., additional, Liguori, R., additional, Sensi, M., additional, Cocozza, S., additional, Filla, A., additional, and Montagna, P., additional
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- 1998
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9. d-Lysine and non-enzymatic glycation
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Ceriello, A., primary and Sensi, M., additional
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- 1994
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10. d-Lysine reduces the non-enzymatic glycation of proteins in experimental diabetes mellitus in rats
- Author
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Sensi, M., primary, De Rossi, M. G., additional, Celi, F. S., additional, Cristina, A., additional, Rosati, C., additional, Perrett, D., additional, Andreani, D., additional, and Di Mario, U., additional
- Published
- 1993
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11. A charge selectivity impairment in protein permselectivity is present in type 2 diabetes
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Morano, S., primary, Pietravalle, P., additional, De Rossi, M. G., additional, Mariani, G., additional, Cristina, G., additional, Medici, F., additional, Sensi, M., additional, Andreani, D., additional, and Di Mario, U., additional
- Published
- 1993
- Full Text
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12. Nuclear inheritance of resistance to antimycin A in Saccharomyces cerevisiae
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Lucchini, G., primary, Carbone, M. L., additional, Cocucci, M., additional, and Sensi, M. L., additional
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- 1979
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13. Prospective study of lymphocyte subsets in subjects genetically susceptible to Type 1 (insulin-dependent) diabetes
- Author
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Pozzilli, P., primary, Sensi, M., additional, Al-Sakkaf, L., additional, Tarn, A., additional, Zuccarini, O., additional, and Bottazzo, G. F., additional
- Published
- 1984
- Full Text
- View/download PDF
14. Book reviews
- Author
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Pyke, D.A., primary, Taljedal, I.-B., additional, Viberti, G.C., additional, Sheldon, Joanna, additional, and Sensi, M., additional
- Published
- 1982
- Full Text
- View/download PDF
15. Inhibition of killer cell cytotoxicity induced by carbimazole in vitro
- Author
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Pozzilli, P., primary, Sensi, M., additional, and Andreani, D., additional
- Published
- 1982
- Full Text
- View/download PDF
16. Sera from diabetic pregnant women contain reduced titres of inhibiting factors on killer cell activity
- Author
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Zuccarini, O., primary, Sensi, M., additional, Gargiulo, P., additional, Pozzilli, P., additional, Tiberti, C., additional, Pachi, A., additional, and Fallucca, F., additional
- Published
- 1985
- Full Text
- View/download PDF
17. Increased killer cell activity in insulin dependent (Type 1) diabetes mellitus
- Author
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Sensi, M., primary, Pozzilli, P., additional, Gorsuch, A. N., additional, Bottazzo, G. F., additional, and Cudworth, A. G., additional
- Published
- 1981
- Full Text
- View/download PDF
18. Late abstracts 186–187
- Author
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Jaehne, J., primary, Meyer, H. -J., additional, Wittekind, Ch., additional, Maschek, H., additional, Pichlmayr, R., additional, Jacobi, G., additional, Weiermann, G., additional, Vitzthum, H. Gräfin, additional, Schwabe, D., additional, Manegold, Ch., additional, Krempien, B., additional, Kaufmann, M., additional, Bailly, M., additional, Doré, J. -F., additional, Fodstad, Ø., additional, Kjønniksen, I., additional, Brøgger, A., additional, Flørenes, V. A., additional, Pihl, A., additional, Aamdal, S., additional, Nesland, J. M., additional, Geldof, A. A., additional, Rao, B. R., additional, De Giovanni, C., additional, Lollini, P. -L., additional, Del Re, B., additional, Scotlandi, K., additional, Nicoletti, G., additional, Nanni, P., additional, Van Muijen, G. N. P., additional, Van Der Wiel-Miezenbeek, J. M., additional, Cornelissen, L. M. H. A., additional, Jansen, C. F. J., additional, Ruiter, D. J., additional, Kieler, J., additional, Oda, Y., additional, Tokuriki, Y., additional, Tenang, E. M., additional, Lamb, J. F., additional, Galante, E., additional, Zanoni, F., additional, Galluzzi, D., additional, Cerrotta, A., additional, Martelli, G., additional, Guzzon, A., additional, Reduzzi, D., additional, Barberá-Guillem, E., additional, Barceló, J. R., additional, Urcelay, B., additional, Alonso-Varona, A. I., additional, Vidal-Vanaclocha, F., additional, Bassukas, I. D., additional, Maurer-Schultze, B., additional, Storeng, R., additional, Manzotti, C., additional, Pratesi, G., additional, Schachert, G., additional, Fidler, I. J., additional, Grimstad, I. A., additional, Rutt, G. Th., additional, Riesinger, P., additional, Frank, J., additional, Neumann, G., additional, Wissler, J. H., additional, Bastert, G., additional, Liebrich, W., additional, Lehner, B., additional, Gonzer, S., additional, Schlag, P., additional, Vehmeyer, K., additional, Hajto, T., additional, Gabius, H. -J., additional, Funke, I., additional, Schlimok, G., additional, Bock, B., additional, Dreps, A., additional, Schweiberer, B., additional, Riethmüller, G., additional, Nicolai, U., additional, Vykoupil, K. -F., additional, Wolf, M., additional, Havemann, K., additional, Georgii, A., additional, Bertrand, S., additional, N'Guyen, M. -J., additional, Siracky, J., additional, Kysela, B., additional, Siracka, E., additional, Pflüger, E., additional, Schirrmacher, V., additional, Boyano, M. D., additional, Hanania, N., additional, Poupon, M. F., additional, Sherbet, G. V., additional, Lakshmi, M. S., additional, Van Roy, F., additional, Vleminckx, K., additional, Fiers, W., additional, Dragonetti, C., additional, De Bruyne, G., additional, Messiaen, L., additional, Mareel, M., additional, Kuhn, S., additional, Choritz, H., additional, Schmid, U., additional, Bihl, H., additional, Griesbach, A., additional, Matzku, S., additional, Eccles, S. A., additional, Purvies, H. P., additional, Miller, F. R., additional, McEachern, D., additional, Ponton, A., additional, Waghorne, C., additional, Coulombe, B., additional, Kerbel, R. S., additional, Breitman, M., additional, Skup, D., additional, Gingras, M. C., additional, Jarolim, L., additional, Wright, J. A., additional, Greenberg, A. H., additional, N'Guyen, M. J., additional, Allavena, G., additional, Melchiori, A., additional, Aresu, O., additional, Percario, M., additional, Parodi, S., additional, Schmidt, J., additional, Kars, P., additional, Chader, G., additional, Albini, A., additional, Zöller, M., additional, Lissitzky, J. C., additional, Bouzon, M., additional, Martin, P. M., additional, Grossi, I. M., additional, Taylor, J. D., additional, Honn, K. V., additional, Koch, B., additional, Baum, W., additional, Giedl, J., additional, Gabius, H. J., additional, Kalden, J. R., additional, Hakim, A. A., additional, LadÁnyi, A., additional, Timár, J., additional, Moczar, E., additional, Lapis, K., additional, Müller, K., additional, Wolf, M. F., additional, Benz, B., additional, Schumacher, K., additional, Kemmner, W., additional, Morgenthaler, J., additional, Brossmer, R., additional, Hagmar, B., additional, Burns, G., additional, Erkell§, L. J., additional, Ryd, W., additional, Paku, S., additional, Rot, A., additional, Hilario, E., additional, Unda, F., additional, Simón, J., additional, Aliño, S. F., additional, Sargent, N. S. E., additional, Burger, M. M., additional, Altevogt, P., additional, Kowitz, A., additional, Chopra, H., additional, Bandlow, G., additional, Nagel, G. A., additional, Lotan, R., additional, Carralero, D., additional, Lotan, D., additional, Raz, A., additional, Skubitz, A. P. N., additional, Koliakos, G. G., additional, Furcht, L. T., additional, Charonis, A. S., additional, Hamann, A., additional, Jablonski-Westrich, D., additional, Jonas, P., additional, Harder, R., additional, Butcher, E. C., additional, Thiele, H. G., additional, Breillout, F., additional, Antoine, E., additional, Lascaux, V., additional, Boxberger, H. -J., additional, Paweletz, N., additional, Bracke, M., additional, Vyncke, B., additional, Opdenakker, G., additional, Castronovo, V., additional, Foidart, J. -M., additional, Camacho, M., additional, Fras, A. Fabra, additional, Llorens, A., additional, Rutllant, M. L., additional, Erkell, L. J., additional, Brunner, G., additional, Heredia, A., additional, Imhoff, J. M., additional, Burtin, P., additional, Nakajima, M., additional, Lunec, J., additional, Parker, C., additional, Fennelly, J. A., additional, Smith, K., additional, Roossien, F. F., additional, La Rivière, G., additional, Roos, E., additional, Erdel, M., additional, Trefz, G., additional, Spiess, E., additional, Ebert, W., additional, Verhaegen, S., additional, Remels, L., additional, Verschueren, H., additional, Dekegel, D., additional, De Baetselier, P., additional, Van Hecke, D., additional, Hannecart-Pokorni, E., additional, Falkvoll, K. H., additional, Alonso, A., additional, Baroja, A., additional, Sebbag, U., additional, Barbera-Guillem, E., additional, Behrens, J., additional, Mareel, M. M., additional, Birchmeier, W., additional, Waterhouse, P., additional, Khokha, R., additional, Chambers, A., additional, Yagel, S., additional, Lala, P. K., additional, Denhardt, D. T., additional, Hennes, R., additional, Frantzen, F., additional, Keller, R., additional, Schwartz-Albiez, R., additional, Fondaneche, M. C., additional, Mignatti, P., additional, Tsuboi, R., additional, Robbins, E., additional, Rifkin, D. B., additional, Overall, C. M., additional, Sacchi, A., additional, Falcioni, R., additional, Piaggio, G., additional, Rizzo, M. G., additional, Perrotti, N., additional, Kennel, S. J., additional, Girschick, H., additional, Müller-Hermelink, H. K., additional, Vollmers, H. P., additional, Wenzel, A., additional, Liu, S., additional, Günthert, U., additional, Wesch, V., additional, Giles, M., additional, Ponta, H., additional, Herrlich, P., additional, Stade, B., additional, Hupke, U., additional, Holzmann, B., additional, Johnson, J. P., additional, Sauer, A., additional, Roller, E., additional, Klumpp, B., additional, Güttler, N., additional, Lison, A., additional, Walk, A., additional, Redini, F., additional, Moczar, M., additional, Leoni, F., additional, Da Dalt, M. G., additional, Ménard, S., additional, Canevari, S., additional, Miotti, S., additional, Tagliabue, E., additional, Colnaghi, M. I., additional, Ostmeier, H., additional, Suter, L., additional, Possati, L., additional, Rosciani, C., additional, Recanatini, E., additional, Beatrici, V., additional, Diambrini, M., additional, Polito, M., additional, Rothbächer, U., additional, Eisenbach, L., additional, Plaksin, D., additional, Gelber, C., additional, Kushtai, G., additional, Gubbay, J., additional, Feldman, M., additional, Benke, R., additional, Benedetto, A., additional, Elia, G., additional, Sala, A., additional, Belardelli, F., additional, Lehmann, J. M., additional, Ladanyi, A., additional, Hanisch, F. -G., additional, Sölter, J., additional, Jansen, V., additional, Böhmer, G., additional, Peter-Katalinic, J., additional, Uhlenbruck, G., additional, O'Connor, R., additional, Müller, J., additional, Kirchner, T., additional, Bover, B., additional, Tucker, G., additional, Valles, A. M., additional, Gavrilovic, J., additional, Thiery, J. P., additional, Kaufmann, A. M., additional, Volm, M., additional, Edel, G., additional, Zühlsdorf, M., additional, Voss, H., additional, Wörmann, B., additional, Hiddemann, W., additional, De Neve, W., additional, Van Den Berge, D., additional, Van Loon, R., additional, Storme, G., additional, Zacharski, L. R., additional, Wojtukiewicz, M. Z., additional, Memoli, V., additional, Kisiel, W., additional, Kudryk, B. J., additional, Stump, D., additional, Piñol, G., additional, Gonzalez-Garrigues, M., additional, Fabra, A., additional, Marti, F., additional, Rueda, F., additional, Lichtner, R. B., additional, Khazaie, K., additional, Timar, J., additional, Greenzhevskaya, S. N., additional, Shmalko, Yu. P., additional, Hill, S. E., additional, Rees, R. C., additional, MacNeil, S., additional, Millon, R., additional, Muller, D., additional, Eber, M., additional, Abecassis, J., additional, Betzler, M., additional, Bahtsky, K. P., additional, Umansky, V. Yu., additional, Krivorotov, A. A., additional, Balitskaya, E. K., additional, Pridatko, O. E., additional, Smelkova, M. I., additional, Smirnov, I. M., additional, Korczak, B., additional, Fisher, C., additional, Thody, A. J., additional, Young, S. D., additional, Hill, R. P., additional, Frixen, U., additional, Gopas, J., additional, Segal, S., additional, Hammerling, G., additional, Bar-Eli, M., additional, Rager-Zisman, B., additional, Har-Vardi, I., additional, Alon, Y., additional, Hämmerling, G. J., additional, Perez, M., additional, Algarra, I., additional, Collado, Ma. D., additional, Peran, E., additional, Caballero, A., additional, Garrido, F., additional, Turner, G. A., additional, Blackmore, M., additional, Stern, P. L., additional, Thompson, S., additional, Levin, I., additional, Kuperman, O., additional, Eyal, A., additional, Kaneti, J., additional, Notter, M., additional, Knuth, A., additional, Martin, M., additional, Chauffert, B., additional, Caignard, A., additional, Hammann, A., additional, Martin, F., additional, Dearden, M. T., additional, Pelletier, H., additional, Dransfield, I., additional, Jacob, G., additional, Rogers, K., additional, Pérez-Yarza, G., additional, Cañavate, M. L., additional, Lucas, R., additional, Bouwens, L., additional, Mantovani, G., additional, Serri, F. G., additional, Macciò, A., additional, Zucca, M. V., additional, Del Giacco, G. S., additional, Pérez, M., additional, Kärre, K., additional, Apt, D., additional, Traversari, C., additional, Sensi, M., additional, Carbone, G., additional, Parmiani, G., additional, Hainaut, P., additional, Weynants, P., additional, Degiovanni, G., additional, Boon, T., additional, Marquardt, P., additional, Stulle, K., additional, Wölfel, T., additional, Herin, M., additional, Van den Eynde, B., additional, Klehmann, E., additional, Büschenfelde, K. -H. Meyer zum, additional, Samija, M., additional, Gerenčer, M., additional, Eljuga, D., additional, Bašić, I., additional, Heacock, C. S., additional, Blake, A. M., additional, D'Aleo, C. J., additional, Alvarez, V. L., additional, Gresser, I., additional, Maury, C., additional, Moss, J., additional, Woodrow, D., additional, von Ardenne, M., additional, Krüger, W., additional, Möller, P., additional, Schachert, H. K., additional, Itaya, T., additional, Frost, P., additional, Rodolfo, M., additional, Salvi, C., additional, Bassi, C., additional, Huland, E., additional, Huland, H., additional, Sersa, G., additional, Willingham, V., additional, Hunter, N., additional, Milas, L., additional, Schild, H., additional, von Hoegen, P., additional, Mentges, B., additional, Bätz, W., additional, Suzuki, N., additional, Mizukoshi, T., additional, Sava, G., additional, Ceschia, V., additional, Zabucchi, G., additional, Farkas-Himsley, H., additional, Schaal, O., additional, Klenner, T., additional, Keppler, B., additional, Alvarez-Diaz, A., additional, Bizzari, J. P., additional, Barbera-Guillem, F., additional, Osterloh, B., additional, Bartkowski, R., additional, LÖhrke, H., additional, Schwahn, E., additional, Schafmayer, A., additional, Goerttler, K., additional, Cillo, C., additional, Ling, V., additional, Giavazzi, R., additional, Vecchi, A., additional, Luini, W., additional, Garofalo, A., additional, Iwakawa, M., additional, Arundel, C., additional, Tofilon, P., additional, Giraldi, T., additional, Perissin, L., additional, Zorzet, S., additional, Piccini, P., additional, Pacor, S., additional, Rapozzi, V., additional, Fink, U., additional, Zeuner, H., additional, Dancygier, H., additional, Classen, M., additional, Lersch, C., additional, Reuter, M., additional, Hammer, C., additional, Brendel, W., additional, Mathé, G., additional, Bourut, C., additional, Chenu, E., additional, Kidani, Y., additional, Mauvernay, Y., additional, Schally, A. V., additional, Reizenstein, P., additional, Gastiaburu, J., additional, Comaru-Schally, A. M., additional, Cupissol, D., additional, Jasmin, C., additional, Missot, J. L., additional, Wingen, F., additional, Schmähl, D., additional, Pauwels-Vergely, C., additional, Poupon, M. -F., additional, Gasic, T. B., additional, Ewaskiewicz, J. I., additional, Gasic, G. J., additional, Pápay, J., additional, Mauvernay, R., additional, Schally, A., additional, Keiling, R., additional, Hagipantelli, R., additional, Busuttil, M., additional, VoVan, M. L., additional, Misset, J. L., additional, Lévi, F., additional, Musset, M., additional, Ribaud, P., additional, Hilgard, P., additional, Reissmann, T., additional, Stekar, J., additional, Voegeli, R., additional, Den Otter, W., additional, Maas, H. A., additional, Dullens, H. F. J., additional, Merriman, R. L., additional, Tanzer, L. R., additional, Shackelford, K. A., additional, Bemis, K. G., additional, Campbell, J. B., additional, and Matsumoto, K., additional
- Published
- 1988
- Full Text
- View/download PDF
19. Mechanism of O2 diffusion and reduction in FeFe hydrogenases
- Author
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Philippe Soucaille, Matteo Sensi, Christophe Léger, Isabelle Meynial-Salles, Charles Gauquelin, Carole Baffert, Jochen Blumberger, Laure Saujet, Robert B. Best, David De Sancho, Adam Kubas, Christophe Orain, Hervé Bottin, Vincent Fourmond, Kubas, A, Orain, C, Sancho, D, Saujet, L, Sensi, M, Gauquelin, C, Meynial-Salles, I, Soucaille, P, Bottin, H, Baffert, C, Fourmond, V, Best, R, Blumberger, J, Léger, C, Department of Physics and Astronomy [UCL London], University College of London [London] ( UCL ), Bioénergétique et Ingénierie des Protéines ( BIP ), Aix Marseille Université ( AMU ) -Centre National de la Recherche Scientifique ( CNRS ), Department of Chemistry [Cambridge, UK], University of Cambridge [UK] ( CAM ), Institut de Biologie Intégrative de la Cellule ( I2BC ), Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Institut de Biologie et de Technologies de Saclay ( IBITECS ), Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés ( LISBP ), Institut National de la Recherche Agronomique ( INRA ) -Institut National des Sciences Appliquées - Toulouse ( INSA Toulouse ), Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Centre National de la Recherche Scientifique ( CNRS ), and Institut de Microbiologie de la Méditerranée ( IMM )
- Subjects
Hydrogenase ,General Chemical Engineering ,Mutant ,Nanotechnology ,Molecular Dynamics Simulation ,Molecular Dynamics ,010402 general chemistry ,Electrochemistry ,[ CHIM ] Chemical Sciences ,01 natural sciences ,Catalysis ,Diffusion ,Molecular dynamics ,Metalloproteins ,Site-Directed ,Clostridium ,CHIM/03 - CHIMICA GENERALE E INORGANICA ,chemistry.chemical_classification ,biology ,010405 organic chemistry ,Chemistry ,Mutagenesis ,Active site ,Electrochemical Techniques ,General Chemistry ,0104 chemical sciences ,Oxygen ,CHIM/02 - CHIMICA FISICA ,Enzyme mecanisms ,Enzyme ,Hydrogen ,Mutagenesis, Site-Directed ,Oxidation-Reduction ,Quantum Theory ,Density functional theory, Electrocatalysis, Enzyme mechanisms, Metalloproteins, Molecular dynamics ,Density functional theory ,Biophysics ,biology.protein ,Electrocatalysis ,Cysteine - Abstract
International audience; FeFe hydrogenases are the most efficient H2-producing enzymes. However, inactivation by O2 remains an obstacle that prevents them being used in many biotechnological devices. Here, we combine electrochemistry, site-directed mutagenesis, molecular dynamics and quantum chemical calculations to uncover the molecular mechanism of O2 diffusion within the enzyme and its reactions at the active site. We propose that the partial reversibility of the reaction with O2 results from the four-electron reduction of O2 to water. The third electron/proton transfer step is the bottleneck for water production, competing with formation of a highly reactive OH radical and hydroxylated cysteine. The rapid delivery of electrons and protons to the active site is therefore crucial to prevent the accumulation of these aggressive species during prolonged O2 exposure. These findings should provide important clues for the design of hydrogenase mutants with increased resistance to oxidative damage.
- Published
- 2016
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