1. [Untitled]
- Author
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Marco A. Cimmino, M. Parodi, Giacomo Garlaschi, Giulia Succio, Enzo Silvestri, Stefania Innocenti, and Simone Banderali
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Arthritis ,Magnetic resonance imaging ,medicine.disease ,Rheumatology ,Surgery ,Psoriatic arthritis ,Internal medicine ,Rheumatoid arthritis ,Synovitis ,Dynamic contrast-enhanced MRI ,Medicine ,business ,Nuclear medicine ,Prospective cohort study - Abstract
This dynamic magnetic resonance imaging (MRI) study is concerned with a prospective evaluation of wrist synovitis in patients with psoriatic arthritis (PsA) in comparison with patients with rheumatoid arthritis (RA) and healthy controls. Fifteen consecutive patients with PsA, 49 consecutive patients with RA, 30 RA patients matched for disease severity with those with PsA, and 8 healthy controls were studied. MRI was performed with a low-field (0.2T), extremity-dedicated machine. After an intravenous bolus injection of gadolinium-diethylenetriaminepentaacetic acid, 20 consecutive fast spin-echo axial images of the wrist were obtained every 18 s. The enhancement ratio was calculated both as rate of early enhancement (REE), which shows the slope of the curve of contrast uptake per second during the first 55 s, and as relative enhancement (RE), which indicates the steady state of enhancement. The REE was 1.0 ± 0.6 in patients with PsA, 1.6 ± 0.7 in consecutive patients with RA, and 0.1 ± 0.1 in controls (p
- Published
- 2005
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