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33 results on '"Wang, Yamei"'

7. Ferroptosis in oligodendrocyte progenitor cells mediates white matter injury after hemorrhagic stroke

Author

Shen, Danmin, primary, Wu, Weihua, additional, Liu, Jing, additional, Lan, Ting, additional, Xiao, Zhongnan, additional, Gai, Kaiyuan, additional, Hu, Liye, additional, Luo, Zhaoli, additional, Wei, Chao, additional, Wang, Xiaotong, additional, Lu, Yabin, additional, Wang, Yamei, additional, Zhang, Chenguang, additional, Wang, Peipei, additional, Zuo, Zhentao, additional, Yang, Fei, additional, and Li, Qian, additional

Published
2022
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8. Calcium functioned carboxymethylated cotton fabric for hemostatic wound dressing

Author

Xueling Feng, Yujun Liu, Peiwen Zhou, Wang Yamei, Dongdong Xiao, Zhiping Mao, Bijia Wang, Xiaofeng Sui, Hong Xu, Zhize Chen, Yi Zhong, and Linping Zhang

Subjects
Polymers and Plastics, medicine.medical_treatment, chemistry.chemical_element, 02 engineering and technology, Femoral artery, Calcium, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Emergency situations, 0104 chemical sciences, Blood loss, chemistry, In vivo, Hemostasis, medicine.artery, Wound dressing, Anesthesia, medicine, 0210 nano-technology, Saline
Abstract

Massive hemorrhage is a frequent cause of human death in the operating room and other emergency situations. Therefore, effective hemostatic wound dressings are essential to save lives. Here we show that, calcium functioned carboxymethylated cotton fabric (MCF-Ca) conveniently prepared by carboxymethylation of cotton fabrics followed by treatment with calcium chloride solution could serve as an effective hemostatic wound dressing. The calcium content of MCF-Ca was determined as 18.11 ± 0.44 mg/g, and the calcium ions were released into a saline solution, a process that reached near-equilibrium within about 2 min. The biocompatible MCF-Ca promoted hemostasis via forming complexes with blood cells, and it showed lower blood clotting index as well as shorter blood clotting time comparing with unmodified CF in vitro. In addition, MCF-Ca exhibited better hemostatic efficiency than CF in vivo, resulting in much shorter hemostasis time and less blood loss in rat liver injury model and femoral artery animal model. In conclusion, MCF-Ca shows good potential to be used as wound dressing for patients with uncontrolled or massive hemorrhage.

Published
2020

9. Facile fabrication of carboxymethyl chitosan/paraffin coated carboxymethylated cotton fabric with asymmetric wettability for hemostatic wound dressing

Author

Yi Zhong, Wang Yamei, Bijia Wang, Xiaofeng Sui, Xueling Feng, Zhize Chen, Dongdong Xiao, Zhiping Mao, Hong Xu, and Linping Zhang

Subjects
Polymers and Plastics, Blood clotting, Chemistry, technology, industry, and agriculture, 02 engineering and technology, Absorption (skin), 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Animal model, Carboxymethyl-chitosan, Hemostasis, Wound dressing, Rat liver, parasitic diseases, Wetting, 0210 nano-technology, Biomedical engineering
Abstract

Achieving effective hemostasis is significant to ensure the survival of the people with acute massive bleeding in the battlefield or daily life in pre-hospital care. In this work, modified cotton fabric with asymmetric wettability (Janus) was prepared using a fast and simple spray-coating strategy, where, one side of the fabric was sprayed with carboxymethyl chitosan solution to achieve hydrophilicity (0°) while the other side with hydrophobicity (152°) was built using paraffin. The hydrophilic surface could provide blood absorption and promote hemostasis, while the hydrophobic surface prevented the excessive blood absorption. The hemostatic efficiency of fabrics was tested in vitro and in vivo. Here, the carboxymethyl chitosan coated carboxymethylated cotton (CS-MCF) and Janus showed better hemostatic capacity than the cotton fabric (CF) in vitro with the lower blood clotting index. Furthermore, the Janus had better hemostatic performance than CF in rat liver animal model, and prolonged the survival time of the rats in carotid artery animal model. Therefore, Janus, with superior hemostatic efficiency over the cotton fabric, has a bright application prospect as hemostatic wound dressing.

Published
2020

14. A phase 1b study evaluating the effect of elacestrant treatment on estrogen receptor availability and estradiol binding to the estrogen receptor in metastatic breast cancer lesions using 18F-FES PET/CT imaging

Author

Jager, Agnes, primary, de Vries, Elisabeth G. E., additional, der Houven van Oordt, C. Willemien Menke-van, additional, Neven, Patrick, additional, Venema, Clasina M., additional, Glaudemans, Andor W. J. M., additional, Wang, Yamei, additional, Bagley, Rebecca G., additional, Conlan, Maureen G., additional, and Aftimos, Philippe, additional

Published
2020
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23. Interfacial fracture toughness of APS bond coat/substrate under high temperature

Author

Qi Hongyu, Wang Yamei, and Yang Xiaoguang

Subjects
Toughness, Materials science, Computational Mechanics, Fracture mechanics, Young's modulus, Indentation hardness, Thermal barrier coating, symbols.namesake, Fracture toughness, Mechanics of Materials, Modeling and Simulation, visual_art, visual_art.visual_art_medium, symbols, Ceramic, Composite material, Tensile testing
Abstract

Thermal barrier coating (TBC) is an essential requirement of a modern gas turbine engine. The TBC failure is the delamination and spallation. The failure mechanism is interfacial expansion mismatch and oxidation of bond coat (BC). The oxidation damage under high temperature results in the reduction of interfacial adhesion. The interfacial fracture toughness is an important property to analyze the TBC failure. Using the simple tensile test, pushout test method and three-point or four-point-bending test and so on, the interfacial fracture toughness of ceramic top coat/BC has been researched in the past. However, the fracture toughness of the BC/substrate due to the Al depletion was very few studied. In this study, a NiCrAlY bond coat by air plasma spray (APS) was deposited. The substrate is directionally solidified superalloy (DZ40M). The Young’s modulus of bond coat was obtained by the nanoindentation and average Young’s modulus of bond coat is 66.9 GPa. Isothermal oxidation was performed at 1,050◦C for 100 h. Using the HXZ-1000 micro-hardness equipment and fracture mechanics approach, the five different times was chosen to test the hardness and the crack length, and then the fracture toughness was obtained. While the oxidation exposure time increased at 1,050◦C, the hardness of the substrate close to the bond coat decreased with the increase of the bond coat in hardness. Meanwhile, the interfacial fracture toughness of the bond coat–substrate decreased because of the Al depletion.

Published
2008

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