32 results on '"Whisstock, James C"'
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2. The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
3. Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor
4. Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism
5. The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1
6. Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities
7. The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
8. Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
9. The first transmembrane region of complement component-9 acts as a brake on its self-assembly
10. PhosContext2vec: a distributed representation of residue-level sequence contexts and its application to general and kinase-specific phosphorylation site prediction
11. Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin
12. Real-time visualization of perforin nanopore assembly
13. Smoothing a rugged protein folding landscape by sequence-based redesign
14. Correction: Corrigendum: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin
15. Brinp1 −/− mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density
16. N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin
17. Structure of the poly-C9 component of the complement membrane attack complex
18. Torso-like mediates extracellular accumulation of Furin-cleaved Trunk to pattern the Drosophila embryo termini
19. Perforin and granzymes: function, dysfunction and human pathology
20. IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
21. High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster
22. Trunk cleavage is essential for Drosophila terminal patterning and can occur independently of Torso-like
23. Maspin is not required for embryonic development or tumour suppression
24. Torqueing about pores
25. Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within Euteleostomi
26. The structural basis for membrane binding and pore formation by lymphocyte perforin
27. Serpins' mystery solved
28. GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
29. AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
30. T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I–bound peptide
31. The matrix refolded
32. The Evolution of Enzyme Specificity in Fasciola spp.
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