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To evaluate the effect of Chinese medicine (CM) treatment on survival time and quality of life (QOL) in patients with small cell lung cancer (SCLC). This was an exploratory and prospective clinical observation. Patients diagnosed with SCLC receiving CM treatment were included and followed up every 3 months. The primary outcome was overall survival (OS), and the secondary outcomes were progression-free survival (PFS) and QOL. A total of 136 patients including 65 limited-stage SCLC (LS-SCLC) patients and 71 extensive-stage SCLC (ES-SCLC) patients were analyzed. The median OS of ES-SCLC patients was 17.27 months, and the median OS of LS-SCLC was 40.07 months. The survival time was 16.27 months for SCLC patients with brain metastasis, 9.83 months for liver metastasis, 13.43 months for bone metastasis, and 18.13 months for lung metastasis. Advanced age, pleural fluid, liver and brain metastasis were risk factors, while longer CM treatment duration was a protective factor. QOL assessment indicated that after 6 months of CM treatment, scores increased in function domains and decreased in symptom domains. CM treatment might help prolong OS of SCLC patients. Moreover, CM treatment brought the trend of symptom amelioration and QOL improvement. These results provide preliminary evidence for applying CM in SCLC multi-disciplinary treatment.

A new adenine glycoside 1, along with a known compound 2, was isolated from Brassica rapa. Its structure was elucidated as 5′-deoxy-5′-methylamino-9-(α-L-lyxofuranosyl)adenine on the basis of extensive spectroscopic analyses.

With the development of advanced high strength steel, especially for dual-phase steel, the model algorithm for cooling control after hot rolling has to achieve the targeted coiling temperature control at the location of downcoiler whilst maintaining the cooling path control based on strip microstructure along the whole cooling section. A cooling path control algorithm was proposed for the laminar cooling process as a solution to practical difficulties associated with the realization of the thermal cycle during cooling process. The heat conduction equation coupled with the carbon diffusion equation with moving boundary was employed in order to simulate temperature change and phase transformation kinetics, making it possible to observe the temperature field and the phase fraction of the strip in real time. On this basis, an optimization method was utilized for valve settings to ensure the minimum deviations between the predicted and actual cooling path of the strip, taking into account the constraints of the cooling equipment′s specific capacity, cooling line length, etc. Results showed that the model algorithm was able to achieve the online cooling path control for dual-phase steel.

A new flavonoid glycoside 1, along with seven known compounds (2–8), was isolated from Viburnum macrocephalum f. keteleeri by repeated column chromatography. Its structure was identified as apigenin-7-O-[6-O-(5-methoxy-3-hydroxy-3-methyl-5-oxovaleryl)]-β-D-glucopyranoside (1) by spectral analysis.

Three new phenolic compounds 1, 2, and 3 have been isolated from Eucommia ulmoides by repeated column chromatography. Their structures were identified as (+)-erythro-7-O-ethylguaiacylglycerol (1), (–)-erythro-7-O-ethylguaiacylglycerol (2), and 1,3-propanediol-2-O-4′ -(3′ ,5′ -dimethoxy-1′ -hydroxymethyl)phenyl ether (3).

A new phenolic compound, schitenoside C (1), and 23 known compounds (2–24), were isolated from Schizonepeta tenuifolia by repeated column chromatography. Their structures were assigned by spectroscopic data interpretation. Among them, compounds 2–5, 7, and 9–23 were isolated from this genus for the first time.

A new phenolic compound 1 was isolated from Viburnum fordiae Hance by repeated column chromatography. Its structure was identified as 7,8-bis-O-isopropylidene-dihydroeugenol (1) by spectral analysis. In addition, compound 1 was evaluated in vitro for its antifungal activity. It was found to exhibit moderate activity against Aspergillus niger.