1. Zur « Lipoidlöslichkeit » von Arzneimitteln
- Author
-
W. Klinger and H. Hanke
- Subjects
Pharmacology ,Chloroform ,food.ingredient ,Neatsfoot oil ,Cell Biology ,Lecithin ,Aminophenazon ,Cellular and Molecular Neuroscience ,chemistry.chemical_compound ,food ,chemistry ,visual_art ,Molecular Medicine ,Organic chemistry ,lipids (amino acids, peptides, and proteins) ,Solubility ,Molecular Biology ,visual_art.artwork - Abstract
The solubility of phenazon, 4-aminophenazon and aminophenazon in heptan, neatsfoot oil, lard, lecithin and chloroform was determined. The results demonstrate that the solubility in chloroform or heptan cannot be taken as a measure of the fat-solubility, and that the solubility of phenazon in lipids has to be taken into consideration in determining the so-called antipyrinspace as a measure of total body water.
- Published
- 1967
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