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This paper presents the reduction of baseline wander noise found in ECG signals. The reduction has been done using wavelet transform inspired error normalized step size least mean square (ENSS-LMS) algorithm. We are presenting a wavelet decomposition-based filtering technique to minimize the computational complexity along with the good quality of output signal. The MATLAB simulation results validate the good noise rejection in output signal by analyzing parameters, excess mean square error (EMSE) and misadjustment.