1. Chromatography with Cyclodextrin-Based Stationary Phases
- Author
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Apryll M. Stalcup and Karen L. Williams
- Subjects
chemistry.chemical_classification ,Chromatography ,Column chromatography ,Countercurrent chromatography ,Cyclodextrin ,Chemistry ,Stereoselectivity ,Organic component ,Enantiomer ,Chromatography column - Abstract
A significant number of the organic components of foods, flavorings, pharmaceuticals, and pesticides are chiral molecules (Ariens, 1988). The role of stereochemistry in biological processes was first recognized more than 100 years ago by Pasteur and van’t Hoff’Le Bel (Pasteur, 1901). Much of the stereoselectivity of these chemicals has remained shrouded in mystery, however, because techniques for chiral separations were not well developed. The fact that enantiomers exhibit identical physical and chemical properties in an achiral environment renders their separation extremely difficult.
- Published
- 1993
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