1. [Pathogenesis, classification and diagnosis of necrotizing soft tissue infections].
- Author
-
Schnürer S, Beier JP, Croner R, Rieker RJ, and Horch RE
- Subjects
- Anti-Bacterial Agents therapeutic use, Combined Modality Therapy, Connective Tissue pathology, Connective Tissue surgery, Debridement, Diagnosis, Differential, Fasciitis, Necrotizing classification, Fasciitis, Necrotizing diagnosis, Fasciitis, Necrotizing pathology, Fasciitis, Necrotizing surgery, Fournier Gangrene classification, Fournier Gangrene diagnosis, Fournier Gangrene pathology, Fournier Gangrene surgery, Gas Gangrene classification, Gas Gangrene diagnosis, Gas Gangrene pathology, Gas Gangrene surgery, Humans, Necrosis, Skin pathology, Skin Diseases, Bacterial pathology, Skin Diseases, Bacterial surgery, Soft Tissue Infections pathology, Soft Tissue Infections surgery, Systemic Inflammatory Response Syndrome classification, Systemic Inflammatory Response Syndrome diagnosis, Systemic Inflammatory Response Syndrome pathology, Systemic Inflammatory Response Syndrome therapy, Skin Diseases, Bacterial classification, Skin Diseases, Bacterial diagnosis, Soft Tissue Infections classification, Soft Tissue Infections diagnosis
- Abstract
Necrotizing soft tissue infections are caused by a variety of pathogens and may affect different types of soft tissue. Even today mortality and lethality are very high. The primary symptoms of necrotizing soft tissue infections are local pain out of proportion, swelling, erythema and crepitation in cases of subcutaneous gas. A systemic inflammatory response syndrome (SIRS) is often associated. During the last decades early recognition and initiation of an adequate therapy were able to reduce lethality to an average of 20%. The physical examination remains the diagnostic gold standard and may be supported by typical findings of imaging technologies, e.g. subcutaneous gas on x-rays and laboratory tests. After diagnosis an adequate antibiotic and surgical therapy should be performed immediately.
- Published
- 2012
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